Gene hunt: could your Child's DNA predict severe tooth decay?
NCT ID NCT00541060
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked for gene changes that might make children more prone to severe tooth decay. Researchers compared 390 young people with many cavities to cavity-free adults. They checked for mutations in genes that affect enamel, the hard outer layer of teeth. The goal is to understand why some kids get severe cavities even with good dental care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify children at high risk for severe cavities, leading to better prevention and treatment strategies.
- What could go wrong
- This is an early genetic study, not a treatment trial. It may not find clear links, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DENTAL CARIES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Hopital Bretonneau
Paris, 75018, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a gentler cleaning method make cavity sealants last longer?
- Can diet and brushing habits predict cavities in children's first adult molars?
- Warm fillings may soothe sensitive teeth — a trial puts it to the test
- Can a new dental device make Kids' cavity fillings less scary?
- Could a simple online quiz replace the dentist's cavity risk exam?
- Could an amino acid replace fluoride in toothpaste? new trial tests arginine against cavities