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Can a bonding layer make Kids' cavity sealants last longer?

NCT ID NCT06608563

Prevention Sponsor: University of Dublin, Trinity College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers at Trinity College Dublin are testing whether adding an adhesive bonding step before placing fissure sealants helps the sealants stay on children's permanent molars and prevents cavities. The trial includes 100 children aged 6 to 12 who are at high risk of tooth decay and need sealants on their first permanent molars. Each molar is randomly assigned to get either the standard sealant or the sealant with an adhesive layer underneath. Dentists check the sealants after one and two years to see how well they stay in place and whether decay progresses.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an adhesive bonding system used under fissure sealants
What this could lead to
If the adhesive helps, dentists could place sealants that last longer and prevent more cavities in children's permanent molars.
What could go wrong
This is a small, single-center study in children, so the results may not apply to all patients or clinics. Sealants can still wear away or decay can still develop even with the adhesive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 12 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: 1. 6 to 12 years of age; 2. Referred for dental treatment at the Dublin Dental University Hospital DDUH) or that are ongoing patients of the Paediatric dentistry clinic; 3. With first permanent molars that are caries free or present caries lesions restricted to enamel (ICDAS 1 to 3) indicated for glass ionomer sealants. 4. Whose parents agreed and consent to participate in the present research; Exclusion criteria: 1. Presence of any developmental defects 2. Presence of any type of restorative/sealant material in the selected tooth; 3. Presence of a dentine shadow (ICDAS 4) or dentine cavitation (ICDAS 5/6) detected clinically and/or radiographically14; 4. Insufficient cooperation to achieve adequate moisture control using cotton roll isolation

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental caries Fissure sealant

Contacts and locations

Locations

  • Dublin Dental University Hospital - Trintiy College Dublin

    Dublin, Dublin, D02 F859, Ireland

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