Can this toothpaste fix cavities before they start?

NCT ID NCT07419763

Completed Disease control Sponsor: Church & Dwight Company, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special toothpaste could help repair early tooth decay. Thirty adults wore a dental device with enamel samples for one week while using different toothpastes. Researchers measured how much the enamel hardened and how much fluoride it absorbed. The goal was to see if the test toothpaste worked better than a regular fluoride toothpaste or a fluoride-free one.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fluoride toothpaste with potassium nitrate and sodium bicarbonate
What this could lead to: If it works, this toothpaste could help reverse early tooth decay and strengthen enamel, reducing the need for fillings.
What could go wrong: This is a small, early-stage study with only 30 people, and it measured lab effects on enamel, not actual cavity prevention. Results may not apply to real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental caries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL CARIES

Contacts and locations

Locations

Therametric Technologies, Inc.

Noblesville, Indiana, 46060, United States

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