Could a new liquid help heal cavities naturally?
NCT ID NCT06727110
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a new material called PILP is safe to use when treating cavities in adults. Thirty participants will have PILP or a placebo applied to their tooth before getting a filling. They will be monitored for six months to check for tooth health, pain, and gum inflammation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PILP (polymer-induced liquid precursor) cement and conditioner
What this could lead to
If safe, this could lead to a new way to treat cavities that helps teeth heal naturally.
What could go wrong
This is a very early safety study with only 30 people, so it is not yet known if PILP works better than standard fillings. There may be unexpected side effects like tooth sensitivity or gum irritation.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California San Francisco, School of Dentistry
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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