Could a new liquid help heal cavities naturally?
NCT ID NCT06727110
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a new material called PILP is safe to use when treating cavities in adults. Thirty participants will have PILP or a placebo applied to their tooth before getting a filling. They will be monitored for six months to check for tooth health, pain, and gum inflammation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PILP (polymer-induced liquid precursor) cement and conditioner
- What this could lead to
- If safe, this could lead to a new way to treat cavities that helps teeth heal naturally.
- What could go wrong
- This is a very early safety study with only 30 people, so it is not yet known if PILP works better than standard fillings. There may be unexpected side effects like tooth sensitivity or gum irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California San Francisco, School of Dentistry
RECRUITINGSan Francisco, California, 94143, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A cleaner look at cavities: does polishing or bleaching skew detection?
- Which filling lasts longer in Kids' teeth? a Head-to-Head test
- A new topical treatment may spare teeth from root canals