Brain scan clues may predict who benefits from epilepsy procedure
NCT ID NCT07399327
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at people with drug-resistant focal epilepsy who are already scheduled for a brain-mapping procedure called SEEG. At the end of that procedure, doctors sometimes use heat (thermocoagulation) to destroy small areas of brain tissue that cause seizures. The study will use advanced MRI scans and blood tests to see if changes in the brain's barrier and electrical signals can predict who will have fewer seizures after the heat treatment. The goal is to find better ways to choose the right targets for this procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SEEG-guided radiofrequency thermocoagulation (RFTC)
- What this could lead to
- If successful, this could help doctors better select which brain targets to treat with thermocoagulation, improving seizure control for people with drug-resistant epilepsy.
- What could go wrong
- This is an early observational study with only 45 participants, so results may not apply to everyone. It focuses on understanding mechanisms, not proving a new treatment works.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Assistance Publique - Hôpitaux Marseille
RECRUITINGMarseille, France
Contact
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