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Zapping the brain without surgery: a new hope for Tough-to-Treat epilepsy

NCT ID NCT06708143

Recruiting now Disease control Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether a noninvasive technique called temporal interference (TI) stimulation can reduce seizures in people aged 6 to 60 with drug-resistant epilepsy. Researchers apply TI stimulation to deep brain areas using external electrodes, aiming to calm overactive circuits without surgery. The main goal is to see if seizure frequency drops by at least half during the treatment period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
temporal interference (TI) stimulation
What this could lead to
If it works, this could offer a noninvasive alternative to brain surgery for controlling seizures in people with drug-resistant epilepsy.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply to everyone. The treatment may not reduce seizures enough to be clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG RESISTANT EPILEPSY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xuanwu Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100053, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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