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Sound waves aimed at the brain could quiet seizures

NCT ID NCT07680842

Recruiting now Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether low intensity focused ultrasound (LIFU) — sound waves delivered through a wearable headband — can reduce seizures in adults with drug-resistant epilepsy. Participants wear the device during treatment sessions, and researchers track seizure frequency and brain activity using EEG and MRI. The goal is to see if this non-invasive approach can safely modulate brain networks linked to seizures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low Intensity Focused Ultrasound (LIFU) delivered via wearable device
What this could lead to
If successful, this could offer a non-invasive, drug-free option to reduce seizures in people with drug-resistant epilepsy.
What could go wrong
This is a small pilot study, so results may not apply broadly. The treatment may not reduce seizures for everyone, and side effects are still being explored.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy epilepsy Epilepsy, Generalized focal epilepsy generalized epilepsy visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG-RESISTANT EPILEPSY EPILEPSY EPILEPSY (TREATMENT REFRACTORY) EPILEPSY COMORBIDITIES EPILEPSY, DRUG RESISTANT EPILEPSY, FOCAL EPILEPSY, GENERALIZED

Contacts and locations

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94107, United States

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