Can a surprise twist help erase trauma? new PTSD trial investigates

This study tests whether adding an unexpected element (like singing) during memory reactivation, combined with the drug propranolol, can reduce physical stress responses to traumatic memories in people with PTSD. Eighty adults with trauma history will be randomly assigned to standard or mismatch reactivation sessions over six weeks. The goal is to see if the mismatch approach better weakens the memory and lowers heart rate and sweat responses during trauma recall.