Magic mushroom therapy for PTSD tested in groups

NCT ID NCT07506395

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether giving psilocybin (the active ingredient in magic mushrooms) in a group setting is safe and feasible for people with PTSD. 36 participants, including veterans, first responders, and survivors of sexual violence, will receive two group dosing sessions. Researchers will monitor side effects and measure changes in PTSD symptoms, depression, and anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
psilocybin
What this could lead to
If this works, it could point toward a new, group-based therapy option for PTSD that may ease symptoms like anxiety and depression.
What could go wrong
This is a very early, small Phase 1 trial with only 36 participants. It focuses on safety and feasibility, not proof of effectiveness. Psilocybin can cause temporary psychological distress.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Interdisciplinary Substance Use and Brain Injury (ISUBI)

    RECRUITING

    Albuquerque, New Mexico, 87131, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

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