HEALTHY

This study tested a new vaccine called IVX-A12 that aims to protect against two respiratory viruses: RSV and hMPV. It involved 264 healthy adults aged 60 to 85 who received either the vaccine or a placebo. The main goals were to check safety and measure the immune response produc…

This study looked at whether giving a COVID-19 antibody treatment (casirivimab+imdevimab) along with the Moderna vaccine changes how well the vaccine works. About 295 healthy adults took part. The goal was to see if the timing between the antibody treatment and the vaccine matter…

This study looked at whether people who had COVID-19 more than 5 months ago need only one dose of the Pfizer mRNA vaccine, instead of the usual two. It included 267 healthy adults aged 18-45 or 65+, some with prior infection and some without. Researchers measured immune responses…

This early-stage study tested a new vaccine formula (V118 Formulation C) in 65 healthy adults to see if it is safe and well-tolerated. Researchers monitored side effects like injection-site reactions and other health events. The study is complete, and results will guide further d…

This early-stage study tested a new vaccine called V330, designed to protect against norovirus—a highly contagious virus that causes vomiting and diarrhea. Researchers gave the vaccine or a placebo to 245 healthy adults split into younger (18-49) and older (60-79) groups. The mai…

This early-stage study tested the safety of a combination of two antibodies (casirivimab and imdevimab) against the COVID-19 virus. It involved 45 healthy adults or those with stable chronic conditions. The goal was to see if the treatment is safe and how the body processes it.

This study tested an investigational drug called ciraparantag to see if it can quickly reverse the effects of the blood thinner rivaroxaban. Sixty-nine healthy adults aged 50 to 75 took rivaroxaban and then received either ciraparantag or a placebo. The main goal was to measure h…

This early-stage study tested a new oral drug called LY3549492 in 92 Japanese adults, some with type 2 diabetes and some healthy. The main goal was to see if the drug is safe and what side effects it might cause. Researchers also measured how much drug gets into the blood and how…

This study tested a drug called ciraparantag to see if it could quickly reverse the effects of the blood thinner apixaban. Sixty healthy adults aged 50 to 75 took part. The goal was to bring blood clotting time back to normal within an hour and keep it stable for several hours.

This study tested whether two special drinks can help the body remove harmful chemicals from the environment, including cancer-causing agents. The trial involved 300 healthy adults, both smokers and non-smokers. Researchers measured toxin levels in urine to see if the drinks impr…

This study tested whether a daily oral pill (DMAU), taken alone or with another hormone (LNG), can safely and temporarily lower sperm count in healthy men to prevent pregnancy. 92 men took the pill or a placebo for 12 weeks. The goal was to see if sperm counts dropped below a lev…

This early-phase study tested a new drug called ABX1100 in 46 healthy volunteers and people with late-onset Pompe disease. The main goal was to check safety and how the drug moves through the body. Researchers gave single or multiple doses by IV and watched for side effects over …

This study checked how well a new ECG device (Masimo INVSENSOR00057) measures heart rate and detects atrial fibrillation (AFib). It included 365 adults—some healthy and some with AFib. The goal was to see if the device works as well as standard ECG measurements.

This early-stage study tested a single oral dose of HB-2121 in 18 adults (some with celiac disease, some healthy) to see if it is safe and how the body processes it. Participants were monitored for 30 days with clinic visits and daily symptom questionnaires. The goal was to check…

This study looked at whether an automated measuring device could improve the accuracy of bladder diaries in women with lower urinary tract symptoms. 187 women (including healthy volunteers) recorded their urine volume using both a traditional paper diary and an automated device o…

This study tested a new blood test that measures platelet activity in people taking aspirin or clopidogrel. Researchers compared it to the current standard test in 112 healthy volunteers and severely obese individuals. The goal was to see if the new test is accurate and could be …

This study tested a smartphone app and wearable device designed to encourage physical activity and healthy eating in adults aged 60 to 80. Researchers compared the app to standard health education in 237 participants, measuring how often people used the app and changes in quality…

This study tested whether atenolol, a widely used beta blocker, can prevent bone loss in the hip and lower back of postmenopausal women. 420 healthy women aged 50-75 took either atenolol or a placebo. The goal was to see if this common drug could help maintain bone density and re…

This study tested a vaccine called G03-52-01 in 622 healthy adults to see if it is safe and can produce antibodies that neutralize botulinum toxin, the cause of botulism. Participants received either the vaccine or a placebo, and researchers measured immune responses and side eff…

This study tested whether gargling with a mouthwash containing cetylpyridinium chloride and zinc can reduce cold and flu symptoms. 150 healthy adults either brushed their teeth alone or brushed and then gargled with the mouthwash twice daily for 90 days. Researchers tracked how m…

This study looked at whether a 12-week volleyball-specific warm-up program (called VOLLEY12+) could improve balance and movement control in teenage male volleyball players. Twenty-four players aged 15 to 17 took part, with half doing the special warm-up and half doing their usual…

This study tested whether a higher-than-normal dose of MK-8527, a once-monthly pill to prevent HIV, affects heart rhythm. 42 healthy adults took the study drug, a placebo, or an active control. The main goal was to measure changes in the QT interval, a key heart rhythm marker. Th…

This early-stage study tested a new drug called RAY1225 in 68 healthy and obese adults to see if it is safe and how the body processes it. Researchers measured side effects, weight changes, and waist size. The goal is to gather initial safety data before larger trials can explore…

This study looked at whether a cocoa drink rich in flavanols could protect blood vessel function and blood pressure in healthy older adults (65+) during 2 hours of sitting. Twenty participants drank either a high-flavanol or low-flavanol cocoa before sitting, and their artery hea…

This study tested a mushroom blend in 40 healthy adults aged 30–60 who sometimes have mild stomach issues like bloating or irregularity. Researchers measured changes in digestion, mood, and gut bacteria over time. The goal was to see if the mushrooms could improve gut health and …

This study tested a new drug called SJP-001 to see if it could ease hangover symptoms after drinking alcohol. 47 healthy adults who drink moderately took either SJP-001, a placebo, or common drugs like fexofenadine and naproxen along with alcohol. Researchers measured how the dru…

This study tested whether a single session of laser treatment right after gum graft surgery could reduce pain and help the wound heal faster. 36 healthy adults took part, and half received the laser while the other half got standard care. Researchers measured pain levels, wound s…

This study tested whether progressive relaxation exercises (a method of tensing and relaxing muscles) could help first-year nursing students feel less stressed and more resilient before starting clinical practice. 80 students were split into two groups: one did eight relaxation s…

This study tested a 4-week movement program called Dance-Walk in 117 adults looking to improve their mental health. Participants either started the program right away or waited. The program combined dance and walking to help people feel more connected to their bodies, boost energ…

This study tested if expressive writing—writing about your deepest thoughts and feelings—can help reduce anxiety and depression in young adults. 160 participants wrote for 14 days, either to themselves, to a loved one, or just describing their day. The goal was to see which appro…

This study looked at whether taking sodium bicarbonate (baking soda) before exercise helps well-trained cyclists perform better during a long, intense ride. Nineteen athletes did two lab sessions: one with the supplement and one with a placebo. Researchers measured their time tri…

This study looked at whether listening to music before and after a heart procedure (coronary angiography) helps patients recover better. 210 adults took part, with half listening to music and half receiving standard care. Researchers measured pain, anxiety, vital signs, comfort, …

This study looked at whether a nutritional drink (a mix of cherry, cocoa, and other ingredients) could improve sleep in 15 healthy young football players. Each athlete tried both the drink and a placebo at different times to see if the drink helped them sleep longer or better. Th…

This small study tested two simple tools to help night shift nurses feel better: a quiet room to nap or relax, and glasses that block blue/green light. Five nurses from one hospital took part. The goal was to see if these ideas are practical and if they might improve health and r…

This study tested whether cold application (cryotherapy) works as well as numbing gels or sprays to reduce pain from dental injections in children. 100 kids aged 7-10 who needed dental treatment were split into four groups: one got a numbing spray, one got numbing gel, one got co…

This study tested a vibrating device called DigiVibe to see if it reduces pain from injections and fingersticks. Twenty healthy adults who dislike needles received standard shots and shots with the device, then rated their pain. The goal was to find a simple way to ease needle-re…

This study tested a drug called TD-1211 in healthy people and those with constipation caused by opioid painkillers. The goal was to see if it is safe and helps with bowel movements. About 102 adults took part, and they had to stop using other laxatives during the study.

This study tested whether a combination of supplements could improve sleep quality and reduce stress in healthy adults. 115 people took either the supplement or a placebo for a period of time. Researchers measured stress levels, mood, and sleep using questionnaires and a sleep-tr…

This study tested an injection called AYP-101 to reduce fat under the chin (double chin) in 252 healthy adults aged 19 to 65. Participants received either the drug or a placebo, and doctors and patients rated the fat reduction. The goal was to see if the injection safely improves…

This study tested whether taking a daily multivitamin called Vitals+ for 3 months improves thinking, mood, and overall health in healthy adults. 37 volunteers took either the multivitamin or a placebo pill, and researchers measured changes in cognitive function, blood nutrient le…

This study looked at whether taking pine bark extract can help healthy adults feel less tired during intense cycling and recover faster. Fourteen people with at least three years of regular exercise took part. Researchers measured how long they could cycle before exhaustion and c…

This study tested whether taking digestive enzyme pills before a heavy meal can help the body break down fats, proteins, and carbs, reducing symptoms like bloating and gas. 24 healthy adults who often feel discomfort after a high-fat meal took either the enzyme supplement or a pl…

This study tested an experimental oral medication, NG101, to see if it could reduce gastrointestinal side effects (like nausea and vomiting) caused by GLP-1 agonist injections, such as semaglutide. 120 healthy adults with a BMI between 22 and 35 took either NG101 or a placebo for…

This study tested a new drug, CAN10, for the first time in humans. It aimed to see if the drug is safe and how the body handles it. The trial included 80 healthy adults and people with mild to moderate plaque psoriasis. The drug was given as a single dose to healthy volunteers an…

This study tested two sedation drugs, remimazolam and midazolam, in 132 healthy adults undergoing upper gastrointestinal endoscopy. The goal was to see which drug allows for a shorter procedure time and better sedation success. Participants did not know which drug they received. …

This study tested an anti-aging face cream on 44 women aged 45 to 65 with sensitive skin and deep wrinkles. Over 60 days, researchers checked how well the cream was tolerated by the skin and eyes, and measured its ability to smooth wrinkles. The goal was to see if the cream could…

This study looked at whether taking a daily rhodiola rosea supplement for 28 days could help basketball players perform better in simulated games and feel less tired. Forty-eight healthy, professional male basketball players took either the supplement or a placebo. Researchers me…

This study tested whether a serum with low amounts of alpha hydroxy acid (AHA) and polyglutamate acid is safe for people with post-inflammatory hyperpigmentation (dark spots after skin injury). 34 healthy Malaysian adults used the serum for 8 weeks. Researchers checked for side e…

This study tested a cream made from natural plant extracts, niacinamide, and arbutin for its ability to safely lighten dark spots left after skin inflammation. Twenty-five healthy Malaysian adults used the cream for 20 weeks, and researchers checked their skin at several points. …

This study tested whether taking a probiotic called Weizmannella coagulans BC99 for 12 weeks helps healthy adults (ages 18-35) digest protein better and improve muscle and athletic performance. Researchers measured changes in digestive enzymes, amino acids, body composition, and …

This study tested a new gymnastics routine called "SI Kumbang" in 66 healthy women aged 60-70. Participants did the exercises three times a week for three months. Researchers measured their heart-lung fitness, muscle strength, balance, and immune markers to see if SI Kumbang work…

This study aimed to find the best way to recruit nurses and nursing assistants from European Union countries to work in Denmark. Over 110,000 people were sent different recruitment messages on social media to see which ones got a response. The goal was to help public health organ…

This study looked at how healthy adults digest and use two forms of milk protein: intact casein and pre-digested (hydrolyzed) casein. 26 healthy volunteers with a BMI between 18 and 25 took part. The goal was to measure how much protein the body actually absorbs and how the body …

This study tested how much discomfort people feel when transcranial magnetic stimulation (TMS) is applied to different areas of the scalp and with different settings. Twenty healthy adults rated their pain using a questionnaire. The goal was to find which spots and settings are m…

This study aims to develop a method to measure how the body breaks down tryptophan, an essential amino acid. Ten healthy adults aged 18-45 will take a special tracer and provide blood and urine samples. The goal is to eventually use this method to improve nutrition for preterm ba…

This study looked at whether using softer, more flexible materials for intravenous catheters (cannulas) can reduce irritation and damage to veins. 27 healthy adults each had two catheters placed in opposite arms—one standard and one softer—and were monitored for up to 72 hours. T…

This study enrolled 26 healthy adults to see how different airflow settings on two new high-flow nasal cannula (HFNC) devices affect lung aeration. Participants tried various flow rates while their lung volume and comfort were measured. The goal was to understand which settings w…

This study looked at how sleeping at moderate altitude (above 1000 meters) affects oxygen levels in healthy adults. 44 participants had sleep tests at both low and moderate altitude to compare time spent with low oxygen. The goal was to understand how short descents to lower alti…

This study looks at how a common antifungal drug (itraconazole) changes the way the body handles an experimental drug called TD-1211. Twenty healthy adults aged 18 to 50 will take a single dose of TD-1211 with and without itraconazole. Researchers will measure drug levels in the …

This early-phase study tested the safety and how the body processes AVP-786 in 48 healthy adult men aged 18-45. Participants received single or multiple doses of the drug or a placebo. The goal was to measure drug levels in the blood and check for side effects, not to treat any d…

This study looked at brain activity in 29 healthy, right-handed adults while they either moved their right hand or felt a vibration that made it seem like their hand was moving. The goal was to find out the fewest number of repetitions needed to see clear brain responses. The res…

This study looked at whether a serotonin receptor called 5-HT7 could be used as a biomarker for multiple sclerosis (MS). Researchers measured how much of this receptor was on different blood cells from 100 people, including healthy volunteers and MS patients on stable treatment. …

This early-stage study tested a new drug, RPT1G, for the first time in humans. Fifty-six healthy adults received either the drug or a placebo to check its safety and how the body processes it. The goal was not to treat any disease, but to gather important safety information for f…

This study tested how different bike saddle designs affect oxygen and carbon dioxide levels in the penis of 14 elite male road cyclists. Riders used a stationary trainer while researchers measured blood gas changes over time. The goal was to see if a new 3D-printed saddle perform…

This study looked at how the drug elpipodect is absorbed, broken down, and removed from the body in 6 healthy adults. Participants gave blood, urine, and stool samples over time to measure the drug and its byproducts. The goal was purely to understand the drug's behavior, not to …

This early-phase study at Yale University tested whether a single dose of cannabidiol (CBD) could change brain inflammation and pain sensitivity in 28 healthy adults. Researchers used brain scans to measure inflammation and a capsaicin (chili pepper) cream to test pain response. …

This study looked at whether repeated cold or warm water baths can help healthy people recover muscle strength and reduce soreness after exercise. Thirty healthy adults took part, and researchers measured muscle strength, soreness, swelling, and other signs of recovery. The goal …

This early-stage study tested a new drug called LY3522348 in 65 healthy adults to check its safety and side effects. Researchers also measured how much of the drug gets into the blood and how fast the body removes it. The study had two parts, lasting up to 8 weeks total. Since it…

This early-stage study tested a new drug called LY3526318 in 16 healthy adults to see how the body absorbs and gets rid of it, and to check for any side effects. Participants took the drug by mouth either once or multiple times. The study did not aim to treat any disease, just to…

This study tested a new, painless ultrasound method to measure tongue stiffness and fat content in 55 healthy adults aged 18-45. The goal was to create a standard protocol for future research on tongue fat accumulation, which is linked to sleep apnea. Participants lay on their ba…

This study followed 198 runners in the 2015 Ultra-Trail Mont-Blanc to see if drinking only when thirsty (versus following a set schedule) helps maintain healthy sodium levels in the blood. Researchers measured sodium before and after the race, along with weight changes and runnin…

This study tested whether a smartphone app called Flourish can improve mental health in students. Over 1,100 students either used the app regularly or received standard mental health resources for six weeks. Researchers measured changes in well-being, depression, anxiety, and str…

This study tested two new foam bandages on healthy volunteers to see if they stay in place as well as current bandages. 135 people wore the dressings on their knee or thigh for up to 7 days. The main goal was to check if the new bandages stayed put without the edges lifting or th…

This study looked at how much of the drug tacrolimus enters the bloodstream when applied as a cream to healthy skin. Twenty-four healthy adults applied the cream twice daily for 14 days. The goal was to measure drug levels and check for side effects, not to treat any disease.

This study looked at how having a meal affects appetite and eating behaviors in 33 healthy adults. Participants completed questionnaires and had blood tests before and after eating to measure hunger, fullness, and related hormones. The goal was to understand if a single meal chan…

This study tested the safety and side effects of a single dose of lebrikizumab (given as a shot under the skin) compared to a placebo in 24 healthy Chinese adults. Researchers also measured how fast the drug enters the blood and how long it stays in the body. The study did not ai…

This study looked at how taking multiple doses of carbamazepine (a common seizure medicine) changes the way the body processes a single dose of an experimental drug called zongertinib. Sixteen healthy men participated. The goal was to understand if carbamazepine affects zongertin…

This study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD could make the LSD experience shorter or less intense. Twenty healthy adults took part. The goal was to understand how these drugs interact with LSD, not to treat any disease.

This early-stage study tested the safety of a new drug called THB335 in 60 healthy adults. Participants received either the drug or a placebo, and researchers monitored side effects and how the drug moved through the body. The goal was to gather safety information, not to treat a…

This study tested whether a single pill containing two heart medicines (ticagrelor and aspirin) works the same in the body as taking the two pills separately. Twenty-four healthy adults in Mexico took both forms and had their blood levels measured. The goal was to see if the comb…

This study looked at whether zongertinib tablets made by two different manufacturers are absorbed the same way in the body. It involved 56 healthy adults who took a single dose of each version at different times. The goal was to check bioequivalence, not to treat any disease. No …

This study tested whether using the Physitrack app at home helps handball players follow their exercise routines and improve their jumping ability. Twenty-eight healthy adult male handball players were assigned to one of two eight-week home exercise programs through the app. Rese…

This study looked at how the drug bulevirtide (BLV) enters and leaves the bloodstream in people with normal and reduced liver function. Researchers measured drug levels and bile acids, and checked safety after multiple doses. The goal was to understand how liver impairment affect…

This study checked if a generic version of tenofovir disoproxil fumarate (a drug used for HIV and hepatitis B) works the same as the brand-name drug Viread. Forty-seven healthy Chinese adults took both versions under fasting and fed conditions. The goal was to see if the generic …

This study tested the safety and how the body handles a new drug called TML-6 in 72 healthy adults. Participants received single or multiple doses to check for side effects and measure drug levels in the blood. The goal was to gather early safety information, not to treat any dis…

This early-stage study tested whether giving regular insulin as nose drops is safe and tolerable in 24 healthy adults. Researchers aimed to find the highest dose that could be given without causing dangerously low blood sugar. The study was completed and focused on safety, not on…

This study looked at how sore calf muscles (DOMS) affect other muscles in the back and legs of 14 healthy young adults. Researchers measured muscle stiffness, strength, balance, and endurance before and after exercise. The goal is to help people understand how one sore spot can i…

This study looked at how the body processes a single dose of the drug cenerimod in people with severe kidney impairment compared to healthy volunteers. A total of 16 adults took part. The goal was to measure drug levels and safety, not to treat any disease.

This study looked at how healthy men absorb, break down, and eliminate a single dose of the drug KBP-5074. Seven men took a radioactive-labeled version of the drug so researchers could track it in blood, urine, and stool. The goal was to understand the drug's metabolism and how i…

This study looked at how the body processes a drug called MK-1084 when taken alone or with two other common drugs (itraconazole and phenytoin) in 28 healthy adults. The goal was to measure drug levels in the blood to understand potential interactions. This is a Phase 1 trial, mea…

This study looked at two different versions of HMPL-523 acetate tablets to see if they are absorbed the same way in the body. Fifty-four healthy Chinese adults aged 18 to 45 took both versions at different times. The goal was to confirm the new formula works just like the origina…

This study tested a new inhaler against a standard one to see how much medicine gets into the body. It involved 40 healthy volunteers who used both inhalers in a crossover design. The goal was simply to compare absorption, not to treat any disease.

This early-stage study tested a new oral drug, YUQ-A1007, in 47 healthy adults to see if it is safe and how the body processes it. The drug is designed to treat inflammatory bowel disease (IBD) by targeting the gut. Since this is the first time the drug is given to humans, the ma…

This study tested whether a single dose of Selpercatinib (a cancer drug) changes the heart's electrical activity in 32 healthy adults. Participants received the drug, a placebo, or a positive control in random order. The goal was to measure any effect on the QT interval (a heart …

This study looked at how healthy men absorb, break down, and eliminate a drug called BI 425809. Six men took a single dose, and researchers measured the drug and its byproducts in urine and stool. The goal was to understand the drug's journey through the body, not to treat any di…

This early-stage study tested the safety of a new drug called epaminurad, alone and with naproxen, in 57 healthy adults aged 19 to 50. Researchers measured how the drugs move through the body and checked for side effects. The goal was to gather safety data, not to treat any disea…

This study looked at whether a short, animated video called FAST BEE helps people remember stroke warning signs and what to do. Over 300 healthy adults and teens watched the video and then answered questions. The goal was to see if they could recall the signs, apply them to a mad…

This study looked at how ketamine changes brain activity in areas linked to reward and emotion. Researchers used MRI scans to measure brain responses in 13 healthy adults who had used ketamine before. The goal was to better understand ketamine's effects on the brain, not to test …

This study looked at whether doing leg exercises with a blood flow restriction cuff (which limits blood flow) builds more muscle strength and size than regular weight training. Eight healthy adults took part. The goal was to see if this technique could be a better way to improve …

This completed study looked at the nutrition, emotional well-being, and physical health of 40 people who work in the food supply chain. Researchers measured body composition, diet, stress levels, and quality of life to find differences between active and sedentary workers. The go…

This study looked at how the drug carbamazepine changes the way another drug, evobrutinib, moves through the body. Fourteen healthy adults took both drugs in a specific order, and researchers measured drug levels in their blood. The goal was to understand the interaction, not to …

This study tested a placebo solution that feels like a real nerve block but provides no pain relief. Seventeen healthy volunteers received injections to see if they could tell the difference. The goal is to create a convincing placebo so future studies can more accurately measure…

This early-stage study tested a new drug called ZE50-0134 in 104 healthy adults aged 18 to 55. The main goal was to check if the drug is safe and how the body processes it, not to treat any disease. Participants took single or multiple doses of the drug or a placebo, and some als…

This study looked at whether taking arginine supplements could prevent blood vessel damage caused by the NSAID painkiller celecoxib. 44 healthy male volunteers took either arginine or a placebo alongside celecoxib for a week. Researchers measured changes in blood vessel function …

This study looked at how muscle proteins change when healthy young women exercise one leg and keep the other still. Researchers measured how fast muscles build and break down proteins. The goal was to better understand muscle growth and loss, which could help develop treatments f…

This study looked at 96 adults with and without myofascial pain syndrome to find better ways to measure the condition. Researchers used ultrasound, electrical sensors, and other imaging tools to examine muscles, connective tissue, and blood flow. The goal is to develop objective …

This study looked at how two common stomach acid reducers (famotidine and rabeprazole) affect the levels of the drug nirogacestat in the blood. Twenty-four healthy men took nirogacestat alone and with each acid reducer. The goal was to see if these stomach medications change how …

This study looked at 46 healthy young adults aged 18-25 to see if the size of their arms, forearms, and hands is linked to how well they perform hand tasks and how fast they react. Researchers measured arm lengths and circumferences, then tested hand skills with a pegboard and re…

This small pilot study looked at how certain drinks change appetite-related hormones after a meal in 12 healthy adults. Participants were between 20 and 50 years old with a normal body weight. The goal was simply to measure hormone levels and hunger ratings, not to treat or cure …

This study looked at how well two different tools measure balance during walking in 50 healthy adults aged 20 to 40. The goal was to see which method gives more consistent results. This research may help improve ways to prevent falls in the future.

This study looked at whether eating carbohydrates at the end of a meal (instead of the start) changes blood sugar levels in 22 elite female athletes. Participants wore a continuous glucose monitor for 6 days and followed different meal sequences. The goal was to see if food order…

This study tested tiny particles with microneedles (STAR particles) on the skin of 20 healthy adults. The goal was to find the best way to apply them to create small punctures that could help future topical medications work better. No active drugs were used. The study measured sk…

This study looked at how sleep affects the brain's ability to remember and improve motor skills that were learned just by imagining them. Fifty-one healthy right-handed adults practiced finger movement tasks in their minds, then had their brain activity measured with MEG scans be…

This study tested how breathing diesel exhaust affects the heart and blood vessels in healthy adults aged 50-75. Six volunteers with a specific gene type (GSTM1 null) breathed in three different levels of diesel exhaust for 2 hours each, with two weeks between sessions. Researche…

This study tested whether an audio instructional program about puberty could improve self-concept and healthy behaviors in teenage girls with visual impairment. 46 girls aged 12-18 from two schools in Egypt participated. The program aimed to provide accessible information about p…

This study tested whether brain stimulation works better when people are actively using the brain area being stimulated. 51 healthy adults received transcranial magnetic stimulation (TMS) while doing either a thinking task or a simple perception task. Researchers measured brain a…

This study looked at how the brain helps people move skillfully with their left hand after a right-arm nerve injury. Researchers used MRI scans to compare brain activity in people with and without nerve damage. The goal was to understand brain adaptation, not to test a treatment.

This early-phase study tested the safety and how the body processes a new drug called KBP-5074 in 46 healthy adults. Researchers gave single doses and monitored side effects, vital signs, and drug levels in the blood. The goal was to gather information needed for future studies i…

This study looked at how exercise affects the body on a molecular level, focusing on processes like autophagy (how cells clean themselves). Researchers tested 80 healthy athletes—both elite cyclists and recreational runners—before, during, and after a bike workout. The goal was t…

This early-stage study tested a new drug called LY3876602 in 74 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers measured drug levels in blood and spinal fluid. No treatment was given for any di…

This study aimed to find out the daily amount of iodine that breastfeeding women need to stay healthy and support their babies. Researchers studied 17 mother-infant pairs, measuring iodine intake and loss. The results will help improve dietary guidelines for new mothers.

This study looked at how a new drug (DA-5222) is absorbed by the body when taken alone versus when its three components are taken together. Forty healthy adults each received both treatments in a random order, and researchers measured drug levels in the blood. The goal was purely…

This study looked at how two common drugs—itraconazole (an antifungal) and rifampin (an antibiotic)—change the way the body processes selpercatinib, a cancer medication. Twenty-four healthy adults took part to help researchers measure drug levels in the blood. The goal was purely…

This study measured lung function in 2000 healthy Polish children and teens aged 3-18 to establish what 'normal' breathing looks like. The goal is to create reference charts that doctors can use to better diagnose and monitor lung diseases like asthma. Participants were all healt…

This study looked at how a new drug called BI 3000202 affects the way the body handles two other medicines: rosuvastatin (used for cholesterol) and digoxin (used for heart conditions). Fourteen healthy adults took part. The goal was to measure drug levels in the blood, not to tre…

This study looked at how the antifungal drug fluconazole changes the amount of olomorasib in the blood and how fast the body clears it. Fifteen healthy adults stayed at a research center for 12 overnight visits over about 7 weeks. The results will help doctors understand if dose …

This pilot study involved 6 healthy women who ate biscuits made with a special type of wheat bran that can be traced in the body. Researchers collected breath, urine, blood, and stool samples over 24 hours to measure how the bran is fermented in the gut. The goal was to identify …

This study looked at how different manufacturing batches of the drug evobrutinib are absorbed by the body in 28 healthy adults. The main goal was to compare drug levels and safety between batches. Participants took a single dose under fasting conditions, and researchers measured …

This study looked at whether a massage technique based on the tensegrity principle (how parts of the body work together as a connected system) can improve muscle function. Fifty-four healthy men aged 19-24 received either the special massage or no treatment. Researchers measured …

This study looked at how two experimental drugs (DWC202511 and DWC202512) change the way the body processes another drug (DWP16001) in healthy adults. 18 volunteers took part to measure drug levels and safety. The goal was to gather information, not to treat any disease.

This study looked at how having low blood sugar (hypoglycemia) affects the body's automatic nervous system, which controls things like heart rate and blood pressure. Researchers tested 28 healthy adults to see if a drug called spironolactone could block these effects. The goal wa…

This study tested a new, stronger version of the drug RPH-104 in 130 healthy adults aged 18-45. The goal was to see how safe it is, how the body processes it, and whether it triggers an immune response. No treatment was given for any disease, so this study helps gather important …

This study looked at 156 healthy women aged 30-60 to see if intermittent fasting (eating only during an 8-hour window) or quitting smoking could change DNA markers linked to aging and cancer risk. Participants received personal coaching and optional exercise over 6 months. Resear…

This study looked at whether using a special band to partly block blood flow during light weight training can build strength as well as traditional heavy lifting. Sixteen healthy adults did either low-load blood flow restriction training or standard strength exercises for 16 week…

This early-stage study looked at how safe a new drug called epaminurad is and how it moves through the body. It involved 34 healthy adults who took a single dose of the drug while fasting. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at how caffeine changes oxygen levels in the brain and how that relates to thinking skills like memory. Thirty-seven healthy adults aged 25-35 took part. Researchers used a special light-based technique (fNIRS) to measure brain oxygen while participants did ment…

This study looked at whether showing people their blood sugar levels in real time changes how they think about a milk drink with mulberry leaf extract. 170 healthy or prediabetic adults aged 45-75 took part. The goal was to see if seeing the drink's effect on glucose made people …

This study tested a 6-week training program called the 5-Line Principle of Balanced Intensity Training (BPIT) in 23 healthy adults who already exercise regularly. The program uses five levels of exercise intensity, from low-impact ground moves to high-impact jumps. Researchers me…

This study looked at how muscle strength relates to balance in 72 people, comparing healthy individuals to those with chronic ankle instability or ACL knee injuries. Researchers measured static and dynamic balance using a special platform. The goal was to understand how lower lim…

This study looked at how the way a baby is born (C-section or vaginal delivery) changes the nutrients in breast milk. Researchers analyzed milk from 250 healthy mothers in China to compare levels of sugars, fats, and proteins. The goal was to understand these differences, not to …

This study tested how well the body absorbs a new drug, BI 1015550, when given in different pill forms and with or without food. Twenty-four healthy adults took single doses of the drug in three different ways to compare absorption. The goal was to find the best pill form and und…

This study looked at how taking multiple doses of an experimental drug (BI 1015550) changes the way the body breaks down a common sedative (midazolam). Fifteen healthy men aged 18 to 55 took part. The goal was to see if BI 1015550 speeds up or slows down the metabolism of midazol…

This study used MRI scans to see how fingertips change shape when pressed or rubbed. Eight healthy adults had their index fingers scanned while light forces were applied. The goal was to collect data to create realistic computer models of the finger, which could help improve how …

This study looked at how the brain's electrical activity changes when healthy people get mentally or physically tired. Researchers used non-invasive brain scans (EEG and MEG) to find patterns linked to fatigue. The goal was to better understand these signals, not to treat any dis…

This study followed 18 people with Netherton syndrome, a rare genetic skin disorder, to learn how the disease affects the body over time. Researchers measured immune system markers and skin changes to better understand the condition. No new treatments were tested; the goal was to…

This early-stage study looked at how a new drug called BI 425809 changes the way the body processes four common medicines (midazolam, warfarin, omeprazole, and digoxin). Thirteen healthy men took the drugs in a controlled setting, and researchers measured their blood levels over …

This study looked at how Swedish massage and percussion therapy affect muscle stiffness, soreness, and jump performance after exercise. Twenty-four healthy adults received one of the two treatments. Researchers measured muscle properties and soreness levels to see which therapy w…

This study followed 373 healthy young athletes aged 8-16 from Poland for one year to see how focusing on a single sport, athletic performance, and quality of life relate to injuries. Researchers created athlete profiles and tracked injury types, locations, and recovery. The goal …

This study looked at memory complaints in 426 people, including those with brain tumors, breast cancer, and healthy volunteers. Researchers focused on 'prospective memory'—remembering to do things in the future, like taking medication. They found that cancer patients reported mor…

This study looked at how a cancer drug called selpercatinib (LOXO-292) changes the way the body handles repaglinide, a diabetes medication. Sixteen healthy adults took repaglinide alone and then with selpercatinib to compare blood levels. The goal was to gather safety and drug in…

This study looked at how two different capsule forms of the drug olomorasib are absorbed in the body and whether food changes that. It involved 191 healthy Japanese participants over about 6 weeks. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at how using a smartphone changes the angle of your head and neck when you are sitting versus standing. Researchers measured 30 healthy adults aged 18-30 who use their phones for over an hour daily. The goal was to understand the physical effects of common phone…

This study looked at whether applying cold (cryotherapy) for 20 minutes before or after exercise helps healthy young adults recover faster and perform better. 22 participants were tested on muscle soreness, perceived exertion, and jump performance. The goal was to see if cooling …

This study looked at how the drug MK-4482 is processed by the body and its safety in 16 healthy Chinese men. Participants took single and multiple doses of the drug. The goal was to measure drug levels in the blood and check for side effects. This is an early-stage study with no …

This study looked at how a single dose of THC (the active ingredient in cannabis) changes gene activity and immune signals in the blood of 56 adults—some with HIV and some without. Researchers measured these changes before and after THC infusion to see if the effects differ betwe…

This study looked at how taking the experimental drug BI 1015550 with or without food changes the amount of drug in the blood. 18 healthy adults took a single dose under both conditions. The results help researchers understand the best way to take the drug in future studies.

This study looked at whether taking itraconazole changes how much of another drug, BI 764198, stays in the blood. Fourteen healthy men took both medicines at different times, and researchers measured drug levels. The goal was to understand how these drugs interact, which helps do…

This study tested whether spending 20 minutes quietly observing nature (10 minutes walking, 10 minutes sitting) for 10 sessions over two weeks could improve spiritual well-being in healthy adults. 41 participants were randomly assigned to the nature contemplation group or a contr…

This study looked at how two different forms of MDMA (R-MDMA and S-MDMA) affect healthy people. Researchers measured feelings like mood, empathy, and trust, as well as physical changes like blood pressure and heart rate. The goal was to understand the differences between these tw…

This study tested how the drug olomorasib enters the blood and how long it takes the body to remove it in people with mild, moderate, or severe liver problems compared to healthy people. 46 adults took a single dose and were monitored for up to 6 weeks. The goal was to understand…

This study looked at how the antifungal drug fluconazole changes the way the body processes an experimental drug called BI 425809. Fifteen healthy men took BI 425809 alone and then again while also taking fluconazole. The goal was to measure drug levels in the blood, not to treat…

This early-stage study looked at how a common antifungal drug, itraconazole, changes the levels of two experimental drugs (AVP-923 and AVP-786) in the blood. Twenty-four healthy adults took part to help researchers understand potential drug interactions and safety. The goal was t…

This study looked at how special window films, used to make homes more energy-efficient, affect people's thinking, perception, and health. 41 healthy adults aged 18-40 took cognitive tests and reported their comfort levels. The goal was to see if these quick and cheap home upgrad…

This study looked at 401 medical students to see how many had protection against hepatitis B and varicella-zoster (chickenpox/shingles) viruses. Researchers measured immunity levels and checked vaccination records. The goal was to understand current protection rates, not to test …

This early-stage study looked at how the drug DA-1229_01 moves through the body when taken with food. Thirty-six healthy adults each received a single dose and had their blood levels measured. The goal was to check safety and drug processing, not to treat any disease.

This early-stage study tested a new drug called SUVN-I6107 in 64 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo as a single dose or multiple doses. Researchers also checked for changes in brain activity using …

This study looked at how a new drug, BI 1569912, moves through and leaves the body. Eight healthy men took a single oral dose with a radioactive tracer, plus a tiny intravenous dose with a different tracer. The goal was to measure how much drug is absorbed, how it's broken down, …

This study looked at how experimental knee pain changes the way healthy people walk. 34 adults received two knee injections—one that caused temporary pain and one that did not. Researchers used motion-capture cameras and pain sensitivity tests to see how walking patterns changed …

This early-stage study tested a new drug called HEC30654AcOH in 43 healthy adults to see if it is safe and how the body processes it. Participants received either single or multiple doses of the drug or a placebo. The main goal was to check for side effects and measure drug level…

This study looked at how a new drug, zongertinib, changes the way other medicines are processed in the body. Thirty-two healthy men took zongertinib along with common drugs like blood thinners, cholesterol medicine, diabetes medicine, and a water pill. Researchers measured drug l…

This study looked at how healthy young women balance in different directions (front-back vs. side-to-side) and whether body weight plays a role. 111 women participated, and researchers measured their stability using special tests. The goal was simply to understand normal balance …

This study looked at how the drug MDMA changes brain activity related to risk and reward. Twenty-two healthy adults who had used MDMA before took part. Researchers used brain scans while participants did tasks like looking at faces or resting. The goal was to understand how MDMA …

This early-stage study tested whether a new drug called LY3985297 is safe and well-tolerated in healthy adults. It involved 140 participants who received either the drug or a placebo as a single dose or multiple doses, given into a vein or under the skin. The study also measured …

This study looked at whether a supplement called OliPhenolia®, made from olives, can reduce inflammation caused by exercise and help healthy adults recover faster. 18 healthy adults took either the supplement or a placebo before and after a standard workout. Researchers measured …

This study tested two ways of teaching nursing students how to manage fluid and electrolyte balance in a child trapped under rubble. 69 students were split into three groups: one got a 90-minute lecture, another got a 270-minute session combining lecture with a simulation, and a …

This study looked at how the antibiotic rifampicin changes the way the body processes an experimental drug called BI 425809, which is being developed for Alzheimer's disease. Sixteen healthy men took a single dose of BI 425809 alone and then again after several days of rifampicin…

This study tested whether different smells (like city or nature scents) affect how much people eat in a virtual reality outdoor café. 25 healthy young adults (ages 18-29) took part. The goal was to learn how urban design and scents might help people make healthier food choices.

This early-stage trial tested the safety and tolerability of a new drug called BI 1015550 in 42 healthy men. Participants received either a single dose or multiple doses of the drug. The study focused on side effects and how the drug moves through the body, not on treating any di…

This study looked at how a drug called belzutifan changes the amount of metformin in the blood and urine of 14 healthy adults. Participants took metformin alone, then metformin with belzutifan, and researchers measured drug levels. The goal was to understand the interaction, not …

This study looked at the food habits, dietary practices, and food preferences of 200 older adults aged 60 and above living in Singapore. Researchers interviewed participants from different ethnic backgrounds to better understand their nutritional needs. The goal was to gather inf…

This early-stage trial tested the safety and tolerability of a new drug called MK-1167 in 30 healthy adults. Researchers monitored for side effects and whether participants could complete the treatment. The study did not aim to treat any disease, but to gather important safety in…

This study looked at how a new drug called BI 1291583 moves through and leaves the body. Eight healthy men took a single dose with a radioactive tag so scientists could track it in urine and stool. The goal was to understand how the drug is broken down and eliminated, not to trea…

This study looked at how eating different colored carrots (red, purple-red, and purple) affects the body's ability to absorb beneficial plant pigments called carotenoids and anthocyanins. Twelve healthy adults drank carrot juice from each variety over several weeks, and researche…

This study tested a new mobile health program designed to help young Latina women in Alabama learn about sexual health and feel more confident accessing healthcare. 25 women aged 16-21 who hadn't had a checkup in over a year took part. The program used culturally tailored educati…

This study looked at two different ways to give oxygen to healthy volunteers before anesthesia: one using a mask and a machine that helps breathing, and the other adding high-flow oxygen through the nose. The goal was to see which method raises oxygen levels faster and higher. Th…

This study looked at how certain foods (resistant starch and sodium butyrate) affect compounds made by gut bacteria and how those compounds might influence heart and lung reflexes. Fourteen healthy adults took each supplement for four weeks. The goal was to understand the connect…

This study looked at how two HIV medicines, doravirine and islatravir, move into breast milk in healthy women who were breastfeeding. Twelve mothers took part, and researchers measured the amount of drug in their milk over 24 hours. The goal was to estimate how much of the drug a…

This study looked at how the drug KBP-5074 behaves in people with moderate liver impairment compared to healthy adults. Twelve participants received a single dose to measure drug levels and check for side effects. The goal is to understand if liver problems change how the drug is…

This study tested a wearable device that buzzes when surgical residents slouch during operations. Twelve residents wore the device to see if it helped them stay upright and reduced muscle pain. The goal is to prevent long-term injuries and help surgeons have longer, healthier car…

This study looked at how the drug cenerimod is handled by people with mild or moderate liver problems compared to healthy people. 24 adults received a single dose to measure drug levels and safety. The goal was to understand if liver impairment changes how the drug works, which h…

This study tested whether brain wave measurements (EEG) can predict specific brain activity patterns seen on fMRI scans. 24 healthy adults did attention tasks and neurofeedback training. The goal was to see if EEG could guide personalized brain training without needing an MRI.

This study checked if a Philips pulse oximeter, using Masimo sensors, accurately measures blood oxygen levels in people with different skin colors. 70 healthy adults took part. The goal was to make sure the device works well for everyone, not just those with lighter skin.

This study looked at how a drug called BI 655130 enters the body when injected in different places (belly vs. thigh) and in different doses. It involved 48 healthy adults aged 18 to 50. The goal was to understand the drug's behavior, not to treat any disease.

This study looked at how a 40-minute afternoon nap affects communication between key brain regions. Researchers used brain scans to compare connectivity before and after the nap in 55 healthy adults. They also checked if people who often remember dreams showed different changes t…

This study tested a low-powered microwave imaging system on 50 healthy women aged 18-74 to see if it could measure electrical properties of breast tissue. The goal was to find out if these properties relate to breast density seen on mammograms. Each participant had both breasts s…

This early-stage study tested a single dose of an experimental drug called BI 425809 in 83 healthy men. The main goal was to check for side effects and see how the drug moves through the body. Researchers also compared a liquid form to a tablet and looked at whether food changes …

This study looked at how different parts of the brain work together to help us remember events. Researchers used a gentle magnetic pulse (TMS) to temporarily change brain activity in 41 healthy young adults. They then tested memory and used MRI scans to see how brain networks res…

This study tested whether the probiotic Saccharomyces boulardii can improve the gut's ability to keep harmful substances from leaking into the body. Researchers gave healthy adults either the probiotic or a placebo and measured changes in gut permeability and related markers. The…

This early-stage study tested the safety and tolerability of a new drug called BI 1569912 in 56 healthy Japanese men. Participants received either a single dose or multiple doses of the drug or a placebo. The main goal was to check for side effects and measure how the drug behave…

This study looked at how taking bosentan (a drug that can speed up liver processing) changes the levels of nerandomilast in the blood. Sixteen healthy men took nerandomilast alone and then again after several days of bosentan. The goal was purely to gather safety and dosing infor…

This study tested whether a gentle electrical current applied to the scalp (transcranial electrical stimulation) can improve performance on a challenging computer task that requires quick thinking and hand-eye coordination. 44 healthy adults with advanced degrees completed the ta…

This study looked at how the drug MK-1084 (calderasib) is absorbed, distributed, and removed from the body in 8 healthy adults. Researchers measured levels in blood, urine, and feces over time. The goal was to understand the drug's metabolism and clearance, not to treat any disea…

This completed early-stage study looked at how food and a common stomach-acid drug (esomeprazole) affect a new oral medicine called LY4064809 in 36 healthy adults. Researchers measured drug levels in the blood to understand how the body processes it under different conditions. Th…

This study looked at how the drug calderasib enters the blood when taken as two different tablet types, and whether food changes its absorption. Fifty-two healthy adults participated. The goal was to gather information, not to treat any disease.

This study looked at how the drug BI 1015550 moves through and leaves the body of healthy men. Six participants took a single dose, and researchers measured the drug and its breakdown products in blood, urine, and stool. The goal was to understand how the body handles the drug, n…

This study looked at how Parkinson's disease changes the brain's ability to sense time. Researchers measured eye movements in 40 people (patients and healthy volunteers) while they performed timing tasks. Patients were tested both on and off their usual medication to see how dopa…

This early-stage study tested the safety and how the body processes KBP-5074 in 26 healthy adults and people with mild to moderate kidney impairment. Researchers measured side effects and drug levels in the blood to help design future larger studies. No treatment was given; the g…

This early-stage trial studied the safety and how the body handles multiple doses of an experimental drug called BI 3810477. It involved 47 healthy adults aged 18 to 60. The goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This study looked at how a new HIV medicine (MK-4646) interacts with a tuberculosis drug (rifabutin) in 18 healthy adults. Researchers measured drug levels in the blood to see if taking both together changes how much MK-4646 is absorbed. The goal is to ensure safe and effective d…

This study looked at 27 elite Polish rowers to see how hard exercise changes brain chemicals like serotonin and dopamine, and how energy levels affect performance. Participants did a standard exercise test and had blood tests and questionnaires before, right after, and one hour l…

This study looked at how squatting at different depths (partial, parallel, full) changes leg muscle activity and jump performance. Fourteen healthy, experienced exercisers did squats at each depth while their muscle signals and jump height were measured. The goal was to understan…

This study tested a new device called Tasso+™ that collects blood from the upper arm instead of a vein. The goal was to see if it works as well as a standard needle for lab tests. 200 healthy adults took part, and researchers checked if the samples were good enough and if the dev…

This study looked at how a drug called evobrutinib affects the way the body handles four other common medicines: digoxin, metformin, rosuvastatin, and sumatriptan. Forty healthy adults took part to help researchers understand these interactions. The goal was to gather safety and …

This study aims to develop and validate a test that uses time estimation to detect early emotional disorders in people with neurological diseases. Researchers first need to establish normal reference values by testing 150 healthy volunteers aged 20 to 92. The test measures how em…

This study looked at whether eating a special type of sweet orange ('Rosy Red Valencia') that is rich in certain nutrients (carotenoids) can reduce inflammation and oxidative stress in healthy adults. Twenty healthy men and women ate either the special orange or a regular orange …

This study tested a new high-density EEG method to map brain areas involved in movement, sensation, language, emotion, and thinking. It included 122 people with epilepsy, brain tumors, and healthy volunteers. The goal was to improve understanding of brain function and seizure act…

This study looked at how two parts of the brain, Broca's area and the mid-cingulate cortex, work together to control speech. Twenty-three healthy, right-handed adults had brain scans while doing tasks. The goal was to learn more about the basic brain functions that might help imp…

This study looked at how a new drug called LY4065967 is absorbed, broken down, and removed from the body in 16 healthy men. Participants took a single dose with a tiny radioactive label so scientists could track it in blood, urine, and stool. The goal was purely to understand the…

This study looked at how a new drug called BI 1015550 moves through the bodies of 12 healthy Japanese men. The goal was to measure drug levels in the blood after taking different single doses. This information helps doctors understand the right dose for future studies.

This study looked at whether a supplement called MIB-626 (a form of vitamin B3) could improve physical fitness, muscle energy, and brain function in healthy, highly active adults aged 19 to 40. Participants took either the supplement or a placebo twice daily for 10 weeks, with so…

This early-stage study in 6 healthy men measured how much of the experimental drug BI 425809 enters the bloodstream after swallowing a pill. Participants received a pill plus a tiny radioactive tracer dose into a vein. The goal was to understand the drug's absorption, not to trea…

This study looked at how taking the drug zongertinib with or without food changes the amount that gets into the blood. Sixteen healthy men each took one dose of the drug in two different conditions: after a high-fat meal and on an empty stomach. The results will help doctors deci…

This study looked at whether small genetic molecules (microRNAs) from broccoli can be absorbed into the blood and affect gut bacteria. Twenty healthy adults ate broccoli, and researchers measured these molecules in their blood and stool. The goal was to understand if plant molecu…

This study gave 5 healthy adults a single dose of the drug PF-07304814 mixed with a tiny radioactive tracer to see how the body breaks it down and gets rid of it. Researchers measured the drug and its byproducts in blood, urine, and stool over time. The goal was to understand the…

This study looked at why some people feel a sharp increase in pain when a numbing injection (nerve block) wears off after surgery. Researchers gave 40 healthy adults a nerve block in one arm and measured their pain sensitivity as the numbness faded. The goal was to see if the ner…

This study looked at how drinking coffee or tea at the same time as a new drug called enlicitide changes the amount of drug in the blood. 60 healthy adults took part, and researchers compared drug levels when taken with coffee, tea, or water. The goal is to see if these common dr…

This early-stage study tested a single dose of BI 1015550 in 24 healthy Chinese adults to see how the drug is processed by the body and whether it is safe. Participants were closely monitored for side effects and drug levels in their blood. The study is complete and provides basi…

This study checked how well a computer-controlled treadmill can create precise balance disturbances. Twelve healthy adults walked on the treadmill while sensors measured the treadmill's movements. The goal was to see if the treadmill's actual movements matched what it was command…

This study looked at how different versions of the drug bimagrumab, given alone or together with tirzepatide, behave in the body. It involved 125 healthy adults and lasted about 4.5 months. The main goal was to measure drug levels in the blood, not to treat any disease.

This study looked at whether taking four dietary supplements and making lifestyle changes can alter gene activity and improve health markers in healthy adults aged 30 to 55. Researchers measured changes in blood tests, sleep, physical activity, and gut bacteria over 12 weeks. The…

This early-stage study tested the safety and how the body processes a new drug called DA-7503. It involved 90 healthy adults and elderly people who took either the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood, not to treat any dis…

This study looked at how the drug azvudine is absorbed and cleared in healthy adults (ages 18-45) and healthy elderly people (ages 60-85). 24 volunteers took a single dose and then a daily dose for 7 days. The goal was to measure drug levels in the blood and check for any side ef…

This study looked at how a new drug called BI 1810631 is absorbed, broken down, and removed from the body in 15 healthy men. Part A measured how much of the drug was recovered in urine and stool. Part B compared how well the tablet form works versus a tiny IV dose. The goal was t…

This study looked at how healthy adults process a compound called ornithine phenylacetate (OP). Twenty volunteers aged 40-70 received special tracers and gave blood, urine, and muscle samples. The goal was to understand how OP's nitrogen atoms are used to make other important mol…

This study tested whether a generic version of pramipexole extended-release tablets works the same as the brand-name drug MIRAPEX ER in healthy Chinese volunteers. 49 participants took a single dose of each version under fasting and fed conditions. The goal was to check if the ge…

This study collected blood from 43 healthy adults aged 18-60 to serve as a comparison for a test that looks for cancer cells in the blood. Participants gave about 20 mL of blood at up to 20 visits. The goal was to help make the test more accurate for future cancer patients.

This study checks whether prazosin capsules made in Barceloneta (Puerto Rico) and Ascoli (Italy) are processed the same way in the body. About 69 healthy adults will take the capsules and have blood samples taken. The goal is to confirm the two versions are equivalent, not to tre…

This study looked at whether drinking dairy products after exercise helps bone turnover and reduces inflammation better than a sugary drink or water. Twenty healthy young adults (ages 18-30) took part. Researchers measured bone markers and immune responses in the blood after exer…

This study tested a training program for daycare providers to improve how they interact with children. 200 providers took part, with some getting training and others not. The goal was to see if the training helps children develop better social, emotional, and language skills.

This study aimed to create a reference set of normal nerve fiber density values in the skin of healthy adults. Researchers measured nerve fibers in skin biopsies from 300 healthy volunteers aged 20 to 80. The goal was to improve the accuracy of diagnosing small fiber neuropathy b…

This study looked at how different types of massage at different times of day affect brain activity in 12 healthy male taekwondo athletes. Using EEG, researchers measured brain wave patterns after massage sessions. The goal was to understand if timing matters for recovery, not to…

This study tested a virtual reality (VR) afterschool program for children ages 9 to 17. The goal was to see if kids would use and enjoy the VR system, and to measure how many stayed with the program. 32 children from a community program took part, and researchers tracked their st…

This study followed 600 healthy infants from 2 months to 6 years old to see how being fed mostly breast milk, milk-based formula, or soy-based formula affects their growth, body composition, and brain function. Researchers measured physical development and thinking skills over ti…

This study looked at whether giving iodine supplements to pregnant women with normal thyroid function helps their children's brain development at age 2. Researchers tested 85 children using the Bayley scale. The goal was to see if early iodine can improve thinking and learning sk…

This study looked at whether delgocitinib, taken as a capsule, changes heart rhythms in 40 healthy adults. Researchers compared the drug to a placebo using detailed ECG recordings. The goal was to check for any heart-related safety issues, not to treat a disease.

This study tested a computer model, called a digital twin, to see if it could predict how muscles get stronger and bigger from strength training. 23 healthy adults aged 20-40 with at least a year of training experience did an 8-week program. The goal was to improve training guide…

This study looked at how the body absorbs and processes a new drug called LY4268989 in 144 healthy adults, including people of Japanese and Chinese descent. Researchers measured drug levels in the blood and checked for side effects. The goal was to gather safety and processing in…

This early-phase study tested the safety and how the body processes a single dose of IBI3032 in 40 healthy adults. Participants were divided into groups, some receiving the drug and others a placebo, with some groups also checking if food affects the drug. The main goal was to mo…

This study looked at how taking multiple doses of zongertinib changes the way the body processes three other drugs (midazolam, omeprazole, and repaglinide) in 16 healthy men. Participants received the drugs alone and then again after taking zongertinib for several days. The goal …

This study tested a special 3D-printed pill that people swallow to collect bacteria from the gut. Ten healthy adults took the pill to see if it could safely grab samples from the small intestine and compare them to stool samples. The goal was to check if the pill works well and c…

This study looked at how different carbon fiber brace designs change the forces on the ankle joint. Nine healthy adults wore custom braces while walking, and researchers used a computer model to estimate joint stress. The goal was to improve the model and procedures for future br…

This study looked at how different levels of simulator movement affect pilot performance when using a mixed-reality headset. Thirteen healthy adults completed flight tasks in a simulator with no motion, small motion, or full motion. The goal was to measure how accurately and quic…

This study looked at how a new drug called BI 764198 changes the amount of metformin in the blood. Fourteen healthy adults took metformin with and without BI 764198 to see if the combination affects drug levels. The goal was to gather safety and interaction data, not to treat any…

This study looked at how a new drug called BI 425809 changes the way the body processes another drug, midazolam. It involved 15 healthy men who took both drugs. The goal was to see if BI 425809 affects a key liver enzyme, which could change how other drugs work. This helps doctor…

This study aimed to understand how the brain's wiring changes with age. Ten healthy adults aged 18 to 50 had special MRI scans to map connections between brain regions. The researchers developed new markers to track these changes, but the study did not test any treatment or inter…

This early-stage study tested the safety of a new drug, MH-001, in 58 healthy adults. Participants received either the drug or a placebo to check for side effects and how the drug moves through the body. The goal was to gather safety information, not to treat any disease.

This study looked at how imlunestrant affects the body's processing of other drugs like repaglinide, omeprazole, and digoxin in healthy women who cannot become pregnant. It also tested how another drug, quinidine, changes imlunestrant levels. The goal was to understand safety and…

This study looked at how appetite and food intake change across the menstrual cycle in healthy women aged 18-35. Researchers measured eating habits, hunger, metabolism, and body composition in two different phases of the cycle. The goal was to better understand how hormones may i…

This study looked at how people with dystonia, essential tremor, or Parkinson's disease adapt their eye movements compared to healthy volunteers. Researchers used a special eye-tracking task to measure changes in saccade (quick eye movement) accuracy. The goal was to better under…

This study tested whether a 6-week training program delivered through a mobile app could improve agility and movement control in 19 high school athletes aged 14-18. Researchers measured how often participants used the app and checked their movement quality before and after the pr…

This study tested a new, all-in-one breathing exercise device made in Turkey. 40 healthy adults used either the new device or standard devices for 8 weeks. Researchers measured lung function and breathing muscle strength to see if the new device works as well as existing ones.

This study looked at how taking multiple doses of an experimental drug (BI 1569912) changes the way the body processes three common medicines (repaglinide, midazolam, and bupropion). Eighteen healthy adults took the drugs alone and together, and researchers measured drug levels i…

This study looked at whether drugs that boost serotonin (like some psychedelics) can make healthy people more social and caring compared to drugs that boost dopamine. 122 healthy adults aged 18-40 took part in computer tasks measuring empathy, generosity, and moral decisions. The…

This early-stage study tested whether delgocitinib cream, a treatment for skin conditions like eczema, can cause skin irritation when exposed to light. Thirty-five healthy adults received a single application of the cream and a placebo on different skin spots, then were exposed t…

This study looked at how the drug MK-8527, which may be used to prevent HIV, passes into breast milk. Thirteen healthy mothers who were at least 6 weeks postpartum took a single dose. Researchers measured drug levels in their breast milk, blood, and whole blood over 120 hours to …

This study checked whether two different pill versions of the drug nerandomilast are processed the same way in the body. 64 healthy adults each took a single dose of both versions at different times. The goal was to see if the new version works like the one used in later-stage st…

This study looked at how a drug called sotatercept moves through the body when given as a liquid in an autoinjector pen versus a powder form that needs to be mixed. It involved 146 healthy women who are not able to become pregnant. The goal was to see if the two forms work the sa…

This study looked at how the drug ulonivirine moves through the body in 8 healthy adults. Researchers measured how much of the drug was absorbed, broken down, and eliminated in urine and stool. The goal was to understand the drug's path, not to treat any disease.

This early-stage study involved 8 healthy adults to see how the body absorbs and processes zolmitriptan when taken as a pill versus a nasal spray. Researchers measured heart rate, blood pressure, and drug levels in the blood over 24 hours. The goal was to build a model that predi…

This completed early-stage study involved 8 healthy men to learn how the investigational drug MK-5475 is absorbed, broken down, and removed from the body. Participants received a single intravenous dose containing a radioactive tracer to track the drug's path. The study did not a…

This study checked whether a single dose of the experimental drug BI 1015550 affects the heart's electrical activity in 46 healthy adults aged 18 to 50. Participants received low and high doses of the drug, a placebo, and an active control (moxifloxacin) to compare effects. The m…

This study looked at how the antibiotic erythromycin changes the way a new drug, BI 1291583, stays in the body. Twenty healthy adults took both drugs to measure drug levels. The goal was to gather information, not to treat any disease.

This study checked how consistently a non-invasive device measures the amount of blood the heart pumps per beat (stroke volume) in 12 healthy adults. Participants rested and exercised on a bike while the device recorded their heart function. The goal was to see if the device give…

This study checked the immune status of 1,024 police officers in Bern, Switzerland, against COVID-19 over one year. Researchers looked at how work and home life affected infection risk and how often protective gear was used. The goal was to learn more about virus spread in this g…

This study looked at how the drug nirogacestat affects the way the body processes five common medications in 20 healthy men. Participants took the five drugs alone and then again while also taking nirogacestat. The goal was to see if nirogacestat speeds up or slows down the break…

This study surveyed over 2,000 healthy adults from different racial and ethnic groups to learn how well they understand epigenetics—how environment and behaviors can turn genes on or off. The goal was to find better ways to explain epigenetics so people can make informed decision…

This early-stage study tested an experimental drug called BI 655130 in 36 healthy adults. The main goal was to see how well the drug is absorbed when given as a shot under the skin compared to through an IV. Researchers also checked safety and how the drug behaves in the body. No…

This study tested whether an experimental HIV medicine called ulonivirine (MK-8507) affects heart rhythm. 62 healthy adults received the drug or a placebo, and researchers measured changes in their heart's electrical activity. The goal was to ensure the drug is safe for the heart…

This study looked at whether drinking camel milk after intense cycling helps healthy men recover faster and perform better compared to cow's milk or water. Twelve recreationally active males participated in four lab visits, doing cycling tests and giving blood samples. The goal w…

This study tested a new quick-dissolve tablet (M107 ODT) containing the drug lobeglitazone in 21 healthy adults. Researchers compared how the body absorbs and processes the drug when taken with or without food, and how it compares to the standard Duvie® tablet. The goal was to ga…

This study compared a generic numbing cream (lidocaine and prilocaine) to the brand-name EMLA cream in 40 healthy adults. The goal was to see if the generic version enters the bloodstream at the same rate and amount as the brand-name cream. Participants received both creams at di…

This study looked at how naloxone (a drug that reverses opioid overdoses) works when given as a nasal spray or through an IV. Eight healthy adults took part to help researchers build a computer model that predicts how the drug reaches the brain. The goal was to improve understand…

This study tested whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve physical fitness in healthy athletes. Fifty-nine participants, including young athletes and active middle-aged adults, had their aerobic and anaerobic fitness measured…

This study looked at how small genetic changes in the GLP-1 receptor affect insulin production in healthy adults. Researchers measured insulin release during fasting and when blood sugar was high. The goal was to understand why some people naturally produce more insulin than othe…

This early-stage study tested how a long-acting HIV medication (rilpivirine, given alone or with cabotegravir) moves through the body after a single injection under the skin. 126 healthy adults took part to check safety and drug levels. The goal was not to treat disease, but to g…

This study looked at how a new drug called CKD-508 interacts with two other medicines (midazolam and rosuvastatin) in 24 healthy adult men. The goal was to measure drug levels in the blood, not to treat any disease. Participants took the drugs in a specific order, and researchers…

This study tested whether a headband that reads brain signals and a device that gently stimulates the ear could help healthy adults stay focused and less dizzy during virtual reality tasks. 45 volunteers did attention and motion-sickness tests in VR while some received real stimu…

This study looked at how two types of poor sleep—waking up often or having broken sleep—change the way a painkiller works in the brain. Healthy adults aged 18-48 took part in sleep experiments and then received a study drug to measure pain relief and addiction risk. The goal was …

This study used a special MRI technique with a harmless helium gas to measure how fast air moves through the windpipe. Researchers scanned 24 volunteers, including healthy people and those with COPD or constrictive bronchitis. The goal was to collect real data to improve computer…

This study looked at whether APF530, a drug used to prevent nausea from chemotherapy, causes heart rhythm changes. Fifty-six healthy adults received APF530, a placebo, or other drugs in random order. Researchers measured their heart's electrical activity (ECG) and drug levels in …

This early-stage study tested whether a new eye drop called PRO-232 is safe and tolerable for healthy adults. 28 volunteers received either the eye drop or a placebo. Researchers checked for side effects, changes in eye pressure, and whether the drops caused stinging. The goal wa…

This study looked at how taking VRN110755 with food or a common heartburn drug (rabeprazole) changes its levels in the blood. Twenty-five healthy adults took the drug under different conditions. The goal was to gather information, not to treat any disease.

This early-stage study tested the safety and how the body processes an inhaled drug called DBM-1152A in 20 healthy Chinese adults. Participants inhaled the drug or a placebo once daily for 7 days. The goal was to check for side effects and measure drug levels in the blood, not to…

This study followed 191 healthy teens who were part of the original Beginnings study. Researchers measured their growth and body composition at age 14 to see if the type of diet they had as babies influenced their development. The goal is to understand how early nutrition might a…

This study looked at whether taking the drug BI 425809 with food changes how much of it gets into the blood. Sixteen healthy adults took the drug once with a meal and once on an empty stomach. The results will help doctors know if the drug should be taken with or without food.

This study looked at two different versions of the drug nerandomilast and how food affects the new version. Fifteen healthy adults took single doses in a random order. The goal was to see how the drug is absorbed and processed by the body.

This study tested whether a drug that lowers heart rate (ivabradine) can improve the flexibility of arteries in healthy people. 30 volunteers aged 25-65 with a resting heart rate of 70 or higher took either the drug or a placebo for 8 days. Researchers measured artery stiffness a…

This study tested 35 adults with ankle arthritis or lower limb injury to see how different cuff designs on carbon fiber leg braces affect comfort, walking mechanics, and user preference. Participants walked with several cuff styles while researchers measured foot pressure, pain, …

This study tested how the antifungal drug itraconazole changes the way a new drug, BI 706321, is processed in the body. Fourteen healthy men took a single dose of BI 706321 alone and later with itraconazole. The goal was to measure drug levels in the blood to understand the inter…

This completed study looked at how quickly and completely the drug PF-07054894 is absorbed, broken down, and eliminated from the body. Ten healthy adult men took a single dose with a tiny radioactive tag so scientists could follow it. The goal was to understand the drug's path, n…

This study looked at how two different pill versions of a new drug, BI 1810631, are absorbed in the body. It involved 13 healthy men who took single doses of each version, and also tested how food and a common stomach acid medicine (rabeprazole) affected absorption. The goal was …

This study looked at how eating a high-fat or low-fat meal changes the way the body absorbs HMPL-523 tablets. It involved 18 healthy adults who took the drug under different eating conditions. The goal was to gather information, not to treat any disease.

This study tested a portable headset that sends tiny electrical currents through the skin to help people hear sounds and speech. Researchers worked with 68 healthy Mayo Clinic employees to find the best settings for the device. The goal was to see if this noninvasive method could…

This study looked at how healthy young adults (ages 18-45) perceive effort and energy during upper versus lower body cycling when electrical muscle stimulation is applied. Researchers measured perceived exertion, fatigue, and energy levels in 120 participants. The goal was to und…

This early-stage study tested a new drug called BI 3006337 in 36 healthy Japanese men to see if it is safe and how the body handles it. Participants received either a single shot or multiple shots over 6 weeks. The goal was to gather safety and drug-level data, not to treat any d…

This study tested two different ways to give the experimental drug remternetug: an auto-injector (like an EpiPen) and a traditional prefilled syringe. The goal was to see how much of the drug gets into the bloodstream and how fast the body clears it. 72 healthy adults took part, …

This early-stage study tested a new compound called LEO 158968 in 120 healthy adults aged 18 to 60. The goal was to see what side effects it might cause, how well it is tolerated, and how the body processes it. Participants received either the drug or a placebo, and researchers m…

This pilot study tested whether the BCG vaccine (used for tuberculosis) can change certain markers in the blood and spinal fluid of healthy older adults. Researchers measured immune responses and Alzheimer's-related proteins in 20 participants aged 55-80. The goal was to gather e…

This study looked at arm function and oxygen use in 60 women — some who had breast cancer and some who were healthy. Researchers measured how well the arms work during exercise and how muscles use oxygen. The goal was to understand if breast cancer survivors have reduced arm capa…

This study looked at how iron supplements change the way the body handles a drug called MT-6548. It involved 61 healthy Japanese men who took the drug with and without iron. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at whether electrical impedance tomography (EIT), a radiation-free imaging method, can detect lung damage in children and young adults with cystic fibrosis (CF). Researchers compared EIT results to CT scans to see if it can spot air trapping and lung changes. Th…

This study looked at how fasting changes the way your body and brain use energy. Researchers studied 12 healthy adults to understand the switch from using sugar to using fat for fuel. The goal was to learn more about the biological processes behind fasting's potential health bene…

This study looked at 111 healthy nursing students to see if their natural sleep-wake patterns (chronotype) influenced their motivation and test scores when taught using a flipped learning approach. Researchers measured chronotype with a questionnaire and compared motivation and e…

This study in 8 healthy men aims to understand how the drug BI 1584862 is absorbed, broken down, and eliminated from the body. Participants take a single oral dose with a radioactive label and a tiny intravenous dose with a stable label. Researchers measure the drug and its bypro…

This study looked at how two natural brain chemicals, oxytocin and vasopressin, change the way brain waves interact in 120 healthy adults. Participants received a nasal spray of one of the chemicals and then had their brain activity measured while resting or doing tasks. The goal…

This early-stage study tested the safety of a new drug called PROT-001 in 102 healthy adults. Researchers gave single and multiple doses to see how the body handles the drug and how it interacts with other common medicines. Since participants were healthy, the goal was not to tre…

This study looked at healthy men to see if the proteins in their saliva affect how bitter they find caffeine. Participants tasted caffeine and gave saliva samples for analysis. The goal was to understand natural differences in taste, not to test any treatment.

This study looked at how a high-fat, high-calorie meal changes the way the body absorbs acoramidis, a drug being developed for a heart condition. Eighteen healthy adults took the drug once with food and once without, and researchers measured drug levels in their blood. The result…

This study looked at whether taking monosodium glutamate (MSG) regularly changes how fast the stomach empties and how the body uses protein from food. Thirteen healthy adults with a BMI between 23 and 28 took part. The goal was to understand how MSG might affect digestion, not to…

This study looked at how common prescription and over-the-counter medications affect mood and medication preference in 25 healthy adults. Participants rated their drug liking and value after taking the medication. The goal was to understand these effects, not to treat any disease…

This study looked at how the cancer drug selpercatinib changes the way the body handles midazolam, a sedative. Sixteen healthy adults took both drugs, and researchers measured drug levels in the blood. The goal was to understand potential drug interactions, not to treat any disea…

This study looked at the nerves and cells in the gut of 16 healthy adults aged 18 to 65. Researchers took small tissue samples from the colon to count nerve cells and measure gut barrier function. The goal was to create a normal reference for future studies on diseases like spina…

This study tested whether healthy adults can learn to increase communication between brain regions using neurofeedback—a technique where people see real-time feedback of their brain activity. The goal was to see if boosting this 'network communication' at rest could improve visua…

This study looked at how the experimental drug BI 3000202 is absorbed, broken down, and removed from the body in 12 healthy adults. In one part, participants took the drug as a liquid to measure how much leaves in urine and stool. In another part, they took a tablet and a tiny in…

This study looked at how warm-up programs and shoe type affect movement patterns that can lead to injury in youth soccer players. 64 players aged 13-17 took part. Researchers tested a shortened FIFA11+ warm-up versus a standard one, and compared female-specific cleats to unisex c…

This study looked at 24 national-level male rowers to see how their motivation and body chemistry change during intense exercise. Participants completed a motivation questionnaire, performed a 6000-meter rowing test, and gave blood samples before, right after, and one hour after …

This study looked at how taking multiple doses of a new drug (BI 1015550) changes the way the body processes two other drugs (nintedanib and pirfenidone). Fourteen healthy men took part. The goal was to see if BI 1015550 speeds up or slows down the breakdown of these drugs, which…

This study tested whether a device called Seismofit can accurately measure a person's peak oxygen use (VO2 Max) while they rest, compared to the standard exercise test on a bike. Thirty healthy adults took part. The goal was to see if the Seismofit could replace the need for stre…

This early-stage study tested a new drug called LY3451838 in 53 healthy adults to see if it is safe and how the body handles it. In one part, the drug was given through a vein; in another, it was given just under the skin. The main goal was to check for side effects and measure d…

This study looked at how different exercise intensities affect a brain chemical called BDNF, which helps brain cells grow and stay healthy. Twelve healthy adults aged 18-25 did three types of exercise: high-intensity intervals, moderate continuous running, and light continuous ru…

This early-stage study looked at how well a medicated cream (Metvixia) gets into the skin after using different mechanical techniques like sanding or poking. Ten healthy volunteers had small test areas on their backs treated with various methods. The goal was simply to measure ho…

This study looked at whether eating whole food protein (lean red meat) is as good as or better than a whey protein supplement for building muscle during resistance training. 81 moderately active adults did a 12-week exercise program and were assigned to eat lean red meat, take wh…

This early-stage study tested a new drug called BI 1015550 in 16 healthy Japanese men to see if it is safe and how the body handles it. Participants received a single rising dose of the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood…

This study tested whether a short session of neck stretching can lower blood pressure in 25 healthy adults. Researchers measured blood pressure, tissue stiffness, and heart rate before and after stretching. The goal was to see if stretching relaxes blood vessels and helps the bod…

This study looked at how taking carbamazepine (a seizure medicine) changes the way the body processes nerandomilast, an experimental drug. Sixteen healthy men took both drugs, and researchers measured drug levels in their blood. The goal was to gather safety and interaction data,…

This study looked at how a new drug called MT-8554 changes the way the body processes two common cholesterol-lowering medicines, simvastatin and rosuvastatin. Twenty-eight healthy adult men took part to measure drug levels and check for side effects. The goal was to see if MT-855…

This study looked at how two medical devices—one using pressure waves and the other using mild electrical stimulation—temporarily change blood flow in the lower leg. Twenty healthy adults took part. The goal was to measure blood flow changes, not to treat any disease.

This study followed 2,760 healthy infants from birth to age 3 to understand how nutrition and gut bacteria influence bone development. Researchers measured gut microbiome patterns, diet, and bone strength using ultrasound. The goal was to map normal growth trajectories and see ho…

This study looked at whether a small device worn on the arm (Tasso) can collect blood samples as accurately as standard needle draws after taking the migraine drug zavegepant nasal spray. Fourteen healthy adults took part, and some also tried a butterscotch candy to see if it cha…

This early-stage study tested the safety and how the body processes a single dose of ARC-520, given at different speeds, in 40 healthy adults. The main goal was to check for side effects and measure drug levels in the blood. Since participants were healthy, this study was not mea…

This study tested a new tablet that combines two drugs (etoricoxib and betamethasone) to see if it works the same as taking each drug separately. It involved 42 healthy adults who received single doses under fasting conditions. The goal was to measure how the drugs are absorbed a…

This study tested whether a supplement made from cornelian cherry (a fruit) could improve heart and blood vessel function in 18 healthy amateur long-distance runners over 45 years old. Participants took either the cherry supplement or a placebo for four weeks, then switched after…

This study looked at whether drinking a KETO5 XOGenius beverage every day could improve markers of heart health, blood pressure, cholesterol, and thinking skills. Six healthy adults aged 18 to 50 took part. The goal was to see if the drink might lower risks for heart disease and …

This study looked at how a drug called LY3484356 enters the bloodstream and leaves the body. Sixteen healthy women who cannot become pregnant took a single dose with a tiny radioactive tag. Researchers measured the drug in blood, urine, and stool to understand its absorption and …

This study tested a wearable device that uses electrical stimulation to help stroke survivors improve their walking. Researchers first recorded muscle activity from healthy volunteers to understand normal walking patterns. Then, stroke survivors used the device for about a month …

This study looked at whether eating a diet with inulin (a type of fiber) for 7 days changes how many calories the body burns at rest and after meals. It included 61 healthy or overweight adults. The goal was to understand how this fiber affects energy use, not to treat a disease.

This study looked at how evobrutinib, an experimental drug, changes the way a common birth control pill works in 20 healthy women. Participants took both medications and had their blood levels measured. The goal was to see if evobrutinib affects birth control hormone levels, whic…

This study looked at how much of the experimental drug BI 1015550 gets into the bloodstream when taken as a pill compared to when given directly into a vein. Eight healthy men took part. The results help researchers understand the drug's behavior in the body, which is important f…

This study tested whether a dietary supplement containing oleoylethanolamide, ginger, and lavender oil can change gene activity and blood markers in healthy adults. 92 participants took the supplement daily for 12 weeks and provided blood and urine samples. The goal was to unders…

This early-stage study looked at how the experimental drug DA-1229_01 is processed by the body when taken on an empty stomach. 42 healthy adults participated to measure drug levels in the blood and check for any safety issues. The goal was to gather basic information, not to trea…

This study checked whether a single dose of evobrutinib, an experimental drug, changes the heart's electrical activity (QT interval) in 36 healthy adults. Participants received evobrutinib, a placebo, or another drug for comparison. The goal was to see if evobrutinib could cause …

This study tested whether two different versions of the drug nerandomilast are absorbed the same way in the body. It involved 64 healthy adults who took a single dose of each version on separate days. The goal was to confirm the new version works like the one used in later-stage …

This study measured how fast healthy adults can walk in a figure-8 pattern around two cones. Researchers tested 1,000 people aged 18 and older with no known muscle, bone, or nerve problems. The goal was to create standard reference values for this walking test, which can help doc…

This study looked at how the drug LY3537031 enters the blood and leaves the body in people with different levels of kidney function. 31 adults, some with kidney impairment and some healthy, took a single dose. The goal was to gather safety and processing data, not to treat any co…

This study looked at how eating dinner early or late affects metabolism in healthy adults aged 18-30. Researchers timed meals based on each person's internal body clock. Participants ate either before or after their natural melatonin rise, and blood samples were taken to measure …

This study looked at how a single session of strength training with a metronome (paced beats) affects the brain and nerves that control muscles. Thirty healthy men aged 18 to 40 did different types of paced exercises. The goal was to see if adding natural movement variability spe…

This study tested a new medicine called PF-07264660 in 12 healthy Chinese adults to see if it is safe and how the body processes it. Participants received a single IV dose, with three-quarters getting the real medicine and one-quarter getting a placebo. The study lasted up to 181…

This study looked at 80 adults aged 40-60 to see if sitting for long periods slows down digestion and changes gut bacteria in ways that might lead to colon polyps. Participants wore activity monitors, ate blue muffins to track digestion time, and provided stool samples. The goal …

This study looked at how taking MK-1084 with food, in different pill forms, or with a common heartburn drug changes its levels in the body. 56 healthy adults each took a single dose of MK-1084 under different conditions. The results will help guide how MK-1084 should be taken in …

This study is the first time the experimental drug ZE63-0302 is given to humans. It aims to check the drug's safety and how the body processes it in 82 healthy adults aged 18 to 55. Participants receive either the drug or a placebo, and researchers monitor for side effects and me…

This study looked at how the drug tralokinumab behaves in the body when given as one injection versus two injections. It involved 101 healthy adults aged 18 to 55. The goal was to compare the drug levels and safety of the two injection methods, not to treat any disease.

This study looked at how a single dose of an experimental drug, MK-1084, changes the way the body processes two common medications: rosuvastatin (for cholesterol) and metformin (for diabetes). Sixteen healthy adults took part in a crossover design where each person received the m…

This study looked at how branched-chain amino acids (BCAAs) help build muscle and control blood sugar in 24 healthy young adults. Participants drank a mix of amino acids, with or without BCAAs, and researchers measured muscle protein growth and insulin sensitivity. The goal was t…

This study looked at how food and a common heartburn drug (omeprazole) change the way the body absorbs selpercatinib, a cancer medication. Twenty healthy adults took the drug under different conditions to measure blood levels. The results will help doctors give better instruction…

This study looked at how immune cells in the lungs respond to a TB protein called PPD. Seventeen adults—some with latent TB and some without—received PPD directly into their lungs during a bronchoscopy. Researchers then collected lung cells and used scans to measure immune activi…

This study looked at how the body handles a single dose of the drug MCI-186 in people with mild or moderate liver impairment compared to those with healthy livers. A total of 22 participants received one intravenous infusion. The goal was to measure drug levels in the blood to un…

This early-stage study tested a new drug called BI 425809 in 25 healthy men to see how much of it reaches the brain. Researchers measured drug levels in blood and spinal fluid after different doses. The goal was to understand the drug's safety and how it behaves in the body, not …

This study looked at how the body absorbs empagliflozin, a diabetes medication, when taken as a whole tablet or dissolved in water and mixed with food. Fourteen healthy adults participated in this crossover trial. The goal was to see if taking the pill dissolved in water changes …

This early-stage study tested the safety and how the body processes two experimental drugs (CTL0201 and CTL0202) given together or alone. Forty healthy adults aged 19 to 55 took a single dose and were monitored. The goal was to gather safety information, not to treat any disease.

This study looked at how the brain combines information from faces and voices to decide a person's gender. 38 healthy adults underwent brain scans while performing a gender classification task. The goal was to understand which brain areas are involved and how visual and auditory …

This study looked at how the antifungal itraconazole changes the amount of an experimental drug (BI 1815368) in the blood of 14 healthy men. Participants took the experimental drug alone and later with itraconazole to compare drug levels. The goal was to understand if dose adjust…

This study looked at whether DMT, a psychedelic drug, can reduce pain in 17 healthy adults. Researchers used mild electric shocks to cause pain and compared DMT to ketamine and a placebo. The goal was to see if DMT could be a new option for treating pain conditions like chronic p…

This early-stage study tested a single dose of the drug LY3526318 in 16 healthy women to see how it affects blood flow to the skin after applying a cinnamon-like substance. The study was not designed to treat any disease, but to gather basic information about how the drug works i…

This study looked at how different amounts of a maqui berry extract called Delphinol affect blood vessel function. Ten healthy adults took either a placebo or 60, 120, or 180 mg of Delphinol daily for eight days. Researchers measured blood flow and other markers to find the best …

This study tested how well a small heart monitor patch sticks to the skin for up to 30 days. Fifteen healthy adults wore the patch and reported on comfort and skin reactions. The goal was to see if the patch can reliably record heart signals over a long period without causing ski…

This early-stage study tested the safety and how the body handles a new drug called D-2570 in 100 healthy adults aged 18 to 45. Participants received either the drug or a placebo, and researchers monitored side effects, vital signs, and drug levels in the blood. The goal was to g…

This study looks at how early childhood relationships with caregivers influence the romantic partnerships people form as young adults. About 259 participants from an earlier child development study and their live-in partners will fill out online surveys about their relationships.…

This study looked at how various nutrients change the types and activity of gut bacteria. Instead of having people eat the nutrients, researchers added them directly to fecal samples in the lab. The goal was to understand which nutrients might help or harm gut health, especially …

This study looked at how a single session of low-intensity exercise with blood flow restriction (using a cuff to partially limit blood flow) changes pain perception in 20 healthy young adults. Researchers measured pain thresholds and the body's natural pain control system before …

This study tested a new drug called CT-P6 against the approved drug Herceptin in 200 healthy men. The goal was to see if the body processes both drugs similarly and to check for side effects. Participants received a single injection under the skin.

This study looked at how a single dose of selpercatinib changes the amount of rosuvastatin in the blood of 28 healthy adults. The goal was to understand any drug interactions and check safety. Results help doctors prescribe these medicines together more safely.

This study looked at whether combining arm and leg exercise helps healthy people train longer than leg exercise alone. Ten healthy adults took part in cycling tests to measure endurance. The goal was to see if this approach works, so it could later be tested in people with lung d…

This study looked at how meditation affects attention and emotion regulation in 169 healthy adults aged 25 to 70. Researchers used brain scans (MRI, EEG, MEG) and computer tasks to measure brain activity and stress markers. The goal was to understand the mechanisms behind meditat…

This study looked at how taking bosentan (a drug that affects liver enzymes) changes the amount of another drug, BI 425809, in the blood. Fourteen healthy men took BI 425809 alone and then again with bosentan. The goal was to see if bosentan reduces the levels of BI 425809, which…

This study looked at how imlunestrant enters the blood and leaves the body in women with liver problems compared to healthy women. 27 women took part, and the goal was to understand the drug's behavior, not to treat any condition. Results help guide future dosing for patients wit…

This study looked at how the body absorbs two different combinations of the drugs vicadrostat and empagliflozin. It also checked whether food changes drug levels. Thirty-two healthy adults took a single dose of each combination. The goal was to gather information, not to treat an…

This study looked at how two HIV drugs, azvudine and aluvia, interact in the bodies of 15 healthy adults. Participants took the drugs in different orders over three cycles, with blood tests to measure drug levels and safety. The goal was to gather information for future HIV treat…

This early-stage study looked at how the experimental drug fosmanogepix behaves in the bodies of 54 healthy Chinese adults. Participants received either a single dose or multiple doses of the drug, given by IV or as a pill, to measure safety and how the drug is processed. The goa…

This study tested how a single session of resistance exercise (like lifting weights) with or without extra stretching affects blood vessels and blood pressure in healthy adults. 27 healthy men took part and were measured before, right after, and 30 minutes after exercise. The goa…

This early-stage study tested a new drug, NEU-627, in 74 healthy adults to see if it is safe and how the body handles it. Participants received either the drug or a placebo, and researchers monitored side effects and drug levels in the blood. The goal was to gather safety informa…

This study looked at how cannabidiol (CBD) is absorbed and processed in 24 healthy adults. Researchers measured CBD levels in blood and urine to understand its safety and how the body handles it. The goal was to gather basic information, not to treat any disease.

This study looked at how safe three drugs (JW0104, C2402, and JW0105) are and how the body processes them when taken together or alone. It involved 60 healthy volunteers who took a single dose under fasting conditions. The goal was to gather information, not to treat any disease.

This early-stage study tested the safety and how the body processes two forms of the experimental drug solrikitug in 32 healthy adults, both Japanese and non-Japanese. Participants received the drug under the skin and were monitored for side effects and drug levels. Since this st…

This study looked at how children's brains process logical reasoning and how that connects to their math skills. Researchers used brain scans (fMRI) on 137 healthy children aged 8 to 14 while they solved reasoning problems. They then compared brain activity to math test scores ta…

This study looked at how different levels of kidney function affect the amount of a new medicine (BI 456906) in the blood. The medicine is being developed for obesity and liver problems. 42 adults with or without kidney problems received a single injection. Researchers compared b…

This study looked at how the human brain supports using and improving tools. Researchers used brain scans (fMRI) on 70 healthy, right-handed adults aged 18-65 to see which brain areas are active during tool tasks. The goal was to understand what makes human tool use unique compar…

This small pilot study tested a new, non-invasive way to stimulate a nerve in the ear (the auriculotemporal nerve) in 12 healthy adults. Researchers wanted to see if it could change how the body processes pain signals, like pressure and temperature. The goal was to gather initial…

This study looked at how taking the antifungal drug itraconazole changes the amount of the experimental drug BI 1015550 in the blood. Sixteen healthy men received a single dose of BI 1015550 alone and again while taking itraconazole. The goal was to see if the combination alters …

This study looked at how healthcare practitioners move their hands and fingers when inserting a peripheral IV catheter. Researchers measured the forces applied to the skin and veins, as well as needle angles and finger pressure. The goal is to use this data to create more realist…

This early-stage study tested the safety and side effects of a new drug called LY3985863 in 24 healthy Chinese adults. Participants received multiple doses under the skin or a placebo. The goal was to see how the body processes the drug, not to treat any disease.

This study looked at how nabilone, a cannabis-like drug, changes a brain enzyme called FAAH in 10 healthy adults. Participants took nabilone for one week and had brain scans before and after. The goal was to understand how the drug works in the brain, not to treat any disease.

This study looked at whether using common asthma inhalers for 4 weeks can change how blood vessels work in healthy people aged 18 to 40. Participants used either Ventolin, Symbicort, or a placebo inhaler and had tests like lung function, exercise, and ultrasound of arm arteries. …

This study looked at how much of the germ-killing ingredient chlorhexidine remains in special bandages after being worn for 7 days. It also checked for a chemical called PCA that can form in these bandages. 45 healthy adults took part, and the goal was simply to measure these lev…

This study tested whether children between 6 months and 5 years old can have an MRI brain scan without sedation (medicine to make them sleep). 23 healthy children took part. The goal was to see how many could complete the scan without sedation, which could make the process safer …

This study looked at how the brain recovers after people stop using cannabis. Researchers used brain scans and EEG to measure changes in brain receptors and rhythms over four weeks of abstinence. The study included 162 people who were either cannabis-dependent or healthy non-user…

This early-stage study tested a new drug called BI 425809 in 49 healthy Japanese and Chinese men. The main goal was to check safety and how the drug moves through the body after a single dose. No treatment for any disease was given; this was purely a safety and drug-level study.

This study looked at whether watching someone else perform reaching movements can improve your own ability to do the same task. 60 healthy adults were split into three groups: one watched arm movements, one watched light sequences, and one watched nature videos. Their own reachin…

This study looked at how two common drugs (itraconazole and rifampin) change the levels of KBP-5074 in the blood of 24 healthy adults. It was a phase 1 trial with no treatment for any disease. The goal was to gather safety and dosing information for future research.

This study collected brain PET scans from 41 healthy adults aged 20-65 to create a reference database. Doctors can compare these normal scans to those of epilepsy patients to more precisely locate where seizures start, helping guide surgery when medications fail. The goal is to i…

This study tested a new version of the water pill furosemide given as a shot under the skin, comparing it to the standard IV form. Sixteen healthy adults received both methods to see how well the body absorbs the drug. The goal was to check if the under-the-skin shot works as wel…

This early-stage study tested the safety of a new drug called MORF-440 in 80 healthy adults. Participants received either a single dose or multiple doses to see if it causes side effects. The study is complete and does not aim to treat any disease.

This study measured normal breathing resistance in 122 healthy, non-smoking adults using a technique that requires little cooperation. The goal was to establish reference values for adults, similar to those already used in children. This method could help evaluate lung function i…

This study looked at how raising the head of the bed changes lung movement in 31 healthy adults. Participants lay flat and with their heads raised to 20 and 40 degrees while doctors used ultrasound to measure lung sliding. The goal is to help healthcare providers position patient…

This study looked at how a new drug called imlunestrant affects the way the body processes another drug, midazolam, in healthy women who cannot become pregnant. The goal was to understand potential drug interactions and ensure safety. Twenty healthy participants took part over ab…

This study looked at how caffeine affects anxiety, decision-making, and body awareness in 42 people—some with panic disorder and some healthy. Participants took either caffeine or a placebo and had their brain activity scanned using a powerful MRI machine. The goal was to underst…

This early-stage study tested a new drug, OPT101, in 14 healthy volunteers to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored side effects, vital signs, and lab results. Since this is a first-in-human …

This study looked at how a breathing technique called ELTGOL affects air distribution in the lungs of people with COPD and healthy volunteers. Participants lay on their side while researchers applied gentle pressure to the chest and abdomen. The goal was to understand how these p…

This early-stage study tested the safety and how the body handles a new drug called MT-8554. It involved 135 healthy adults, mostly Caucasian, aged 18 to 55 or older. Researchers monitored vital signs, heart activity, lab tests, and side effects. This study did not aim to treat a…

This study looked at how to best prepare blood platelets so scientists can accurately measure their mitochondria—the tiny powerhouses inside cells. Sixteen healthy adults aged 25-35 gave blood samples after fasting. The goal was to make sure lab procedures give reliable results, …

This study looked at whether letting people choose their own mindfulness exercise (focusing on breath or sounds) leads to better results than being assigned one randomly. Over 240 healthy adults in the UK took part. The goal was to see if choice affects mindfulness levels and the…

This study looked at how the drug MCI-186 is handled by the body in people with mild or moderate kidney problems compared to those with normal kidneys. Thirty adults received a single dose of the drug, and researchers measured its levels in the blood over time. The goal was to un…

This study looked at how a non-invasive brain stimulation technique called tDCS changes brain activity and chemistry in 37 healthy adults. Researchers used advanced brain scans to see the effects during and after a single 30-minute session. The goal is to better understand how tD…

This study looked at how interleukin-6, an immune system molecule, changes the way glucagon (a hormone) lowers amino acid levels in the blood. Twenty-six healthy adults received either a placebo or a drug that blocks interleukin-6, then had their amino acid and hormone levels mea…

This study looked at whether special physical activity cards, combined with Life Kinetik exercises, could improve attention, memory, and problem-solving in healthy middle school students aged 11 to 14. 36 students participated, and researchers compared the new cards to traditiona…

This study looked at whether doing thinking tasks while exercising (dual-tasking) improves movement and brain function in people with COPD. 42 participants were split into two groups: one did standard pulmonary rehab, the other added cognitive tasks to walking and cycling. Resear…

This study tested a new way to measure different types of fat in the blood after eating. Fourteen healthy adults ate a test meal, and researchers collected blood samples to see how the fats were broken down. The goal was to see if a special MRI technique (NMR) could accurately me…

This study tested whether delgocitinib cream, applied to the skin and then exposed to UV light, can cause a photoallergic reaction. Sixty healthy adults aged 18-64 with fair to medium skin types took part. Researchers compared skin reactions between areas with the cream and areas…

This early-phase study tested two experimental drugs, JLP-2302 and JP-1366, in 55 healthy volunteers to see how the body processes them and if they are safe. Participants were adults with a normal body weight and no major health issues. The goal was to gather basic safety and dru…

This study tested two new versions of a tablet (BI 425809) against an older version to see how well the body absorbs each one. It involved 18 healthy adults aged 18 to 55. The goal was simply to compare the formulations, not to treat any disease.

This early-stage study tested a new drug called AVP-786 in 56 healthy adult men to see how the body processes it and whether it is safe. Participants took the drug and were monitored for side effects and drug levels in the blood. The study did not aim to treat any disease, but to…

This study tested a new drug called LEO 153339 in 108 healthy adults to see if it is safe and how the body handles it. Participants received either the drug or a placebo, and stayed in the clinic for up to 12 days for monitoring. The goal was to check for side effects and measure…

This early-stage study tested a tablet made from mulberry twig alkaloids (WH006) in 62 healthy and overweight/obese adults in China. The main goal was to check the drug's safety and how it moves through the body, not to treat obesity. Results will help decide if further studies a…

This study looked at how taking multiple doses of itraconazole (an antifungal) changes the way the body processes a single dose of the experimental cancer drug zongertinib. Sixteen healthy men participated to measure drug levels in the blood. The results will help doctors underst…

This study looked at how taking multiple doses of itraconazole, a strong CYP3A4 inhibitor, changes the way the body processes a single dose of BI 3031185. Fourteen healthy male volunteers participated. The goal was to measure drug levels in the blood to understand the interaction…

This early-stage study tested an inhaled form of the anti-nausea drug granisetron in 36 healthy adults. The goal was to check its safety and how the body processes it, comparing different doses and an IV version. No treatment was given for any disease; the study simply gathered s…

This early-stage study tested the safety and how the body processes ARC-520 in 54 healthy adults aged 18-55. Participants received either the drug or a placebo to check for side effects. The goal was not to treat any disease, but to gather important safety information for future …

This study looked at how a common seizure drug, carbamazepine, changes the amount of mirdametinib in the blood. 36 healthy adults took both drugs to see how the body processes them together. The goal was to understand potential drug interactions, not to treat any disease.

This study looked at brain activity in 64 people (some who had a stroke and some healthy) while they moved their arms with help from a robotic exoskeleton. The goal was to see how different levels of effort change brain signals. The results may help design better rehabilitation e…

This study looked at how a special low lactose milk with added fiber (GOS) affects digestion in 24 healthy Chinese adults. Researchers used MRI scans to measure stomach and gut activity after drinking the milk. The goal was simply to learn more about digestion, not to treat any d…

This study looked at how carbon dioxide (CO2) might cause trouble with thinking or memory. Researchers measured immune cell activity in blood samples from 27 healthy adults after CO2 exposure. The goal was to understand the biological process behind CO2-related cognitive impairme…

This study tested a robotic platform that uses motion cameras to keep a person's head still in real time. Twenty healthy volunteers participated, and no radiation was used. The goal was to collect motion data to help develop better head stabilization methods for future brain radi…

This study tested whether treating fruits like lemons and cherries with melatonin helps the body absorb more of their healthy plant compounds. Twenty-two healthy adults drank juice from treated or untreated fruits and provided urine samples to measure absorption. The goal was to …

This study looked at the types of immune cells in the blood of 40 healthy Danish women aged 18-41. The goal was to create a reference for future studies on how the immune system affects diseases in women of reproductive age. No treatment or intervention was given.

This study looked at whether taking multiple doses of the drug Iclepertin affects how the body processes a common birth control pill (Microgynon) in healthy women aged 18-35. Nineteen participants took the birth control pill with and without Iclepertin, and researchers measured d…

This study looked at how the drug selpercatinib is handled by the body in people with kidney problems compared to healthy people. 37 adults took a single dose of the drug, and researchers measured how much got into the blood and how quickly it was removed. The goal was to gather …

This early-phase study tested a single dose of MT-8554 in 20 healthy men to see how it affects pain perception. Participants underwent a cold pressor test (immersing hand in cold water) and rated their pain on a scale. The study also checked for side effects. Since it involved he…

This study looked at whether people with Complex Regional Pain Syndrome (CRPS) have trouble imagining movements in their mind. Researchers compared 129 adults—some with CRPS, some with other muscle pain, and some healthy—using a questionnaire that measures motor imagery skills. T…

This early-stage study tested the safety and how the body handles a new drug called BI 425809 in 96 healthy young and elderly volunteers. Participants took the drug as tablets once daily for 12 days, and researchers also compared taking it in the morning versus evening. The goal …

This study looked at how the heart's muscle stiffness (fibrosis) changes as people age normally. Researchers used MRI scans and blood tests to measure fibrosis in 74 healthy adults. The goal was to better understand age-related changes in heart function, not to treat any disease.

This study looked at whether patterns in how people use their cell phones (like calls, texts, and movement) are linked to their body's daily cycles, including blood pressure and metabolism. Six healthy adults aged 25-35 with Android phones participated. The goal was simply to obs…

This early-stage study tested the safety and how the body processes a new drug called SR750 in 40 healthy Chinese adults aged 18 to 45. Participants received either the drug or a placebo, and researchers measured drug levels in the blood and monitored for side effects. The goal w…

This study tested three different versions of an experimental drug called BI 456906 in 30 healthy adults. The goal was to see how well each version is absorbed into the body. Participants received a single dose of each version in a random order, and their blood levels were measur…

This early-stage study tested the safety and tolerability of a new drug called SPY001-001 in 96 healthy adults. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moves through the body. The goal was to gather safety in…

This study measured how much radiation a new brain-scan tracer called [18F]PBR111 gives off in healthy people. Six adults (3 men, 3 women) received the tracer and had PET/CT scans for about 2 hours. The goal was to check safety and radiation exposure, not to treat any disease.

This study looked at whether the way antiseptics are applied to the skin before surgery affects how well they kill germs. 122 healthy adults took part. The goal was to see if different application methods lead to better germ reduction, which could help prevent infections during s…

This study looked at how people with congenital amusia (tone deafness) process sound and memory compared to those without it. Researchers used brain scans like EEG, MEG, and MRI to measure brain activity during listening and memory tasks. The goal was to better understand the bra…

This early-stage study looked at how taking the experimental drug BI 1015550 with or without food changes its levels in the blood. Twelve healthy men aged 18 to 55 took the drug under both fed and fasted conditions. The goal was to gather safety and absorption data, not to treat …

This study looked at how broken sleep changes the way healthy adults feel pain and move their shoulders and knees. Thirty participants had their sleep disrupted on purpose, then received painful injections to measure their pain responses. The goal was to understand if poor sleep …

This study tested how accurately the ProSomnus RPMO2 device measures oxygen levels and heart rate. Twelve healthy adults wore the device while their oxygen levels were temporarily lowered in a controlled setting. The results help confirm if the device works well for future use.

This study looked at how the body absorbs two different versions of the experimental drug BI 456906. Sixteen healthy adults each received a single injection of both formulas at different times. The goal was to compare the two formulas, not to treat any disease.

This study looked at whether a brief calf muscle release technique could immediately change how far healthy adults can bend their neck forward and backward. 90 people aged 18-40 took part. Researchers measured neck motion before and right after the calf treatment to see any short…

This study tested whether high doses of a natural cannabis extract (CBD) are safe for healthy athletes who play contact sports like football or rugby. Thirty-four male athletes took a placebo for two weeks, then increasing doses of CBD for several weeks. Researchers monitored for…

This study looked at how healthy adults absorb nutrients from two different blueberry varieties and a blueberry-enriched protein bar. Over three months, 29 participants ate each test meal and provided blood and urine samples. The goal was to see if processed blueberry products of…

This study looked at how two drugs, denifanstat and resmetirom, affect each other in the bodies of 40 healthy adults. The goal was to measure drug levels in the blood to see if taking them together changes how they work. This information helps doctors understand safe dosing for f…

This study checked if a new system called AuReha can measure arm and shoulder movements as accurately as the standard tool (a goniometer). It involved 96 healthy adults who had no arm or trunk movement problems. The goal was to see if AuReha could be a reliable alternative for fu…

This study looked at how food and certain drugs (omeprazole, itraconazole, carbamazepine) affect the amount of a new medicine called LY3484356 in the blood of healthy women who cannot become pregnant. The goal was to understand how the body processes the drug, not to treat any di…

This study looked at how consistently tongue muscle strength and endurance can be measured in healthy children aged 4 to 17. Researchers tested kids twice to see if the results were repeatable. The goal was to gather reliable data, not to treat any condition.

This study tested whether adding a steady beat (metronome or music) to eye-head exercises helps healthy adults improve the reflex that keeps vision clear when moving. Twelve participants completed three training sessions—silence, metronome, and music—while wearing special goggles…

This study looked at 30 women — half with lipedema and half without — to measure differences in leg muscle strength, endurance, walking ability, pain sensitivity, and swelling. Researchers used simple tests like a 6-minute walk and a sit-to-stand test. The goal was to better unde…

This study looked at how well two different tablet forms of the drug miricorilant are absorbed by the body. It involved 18 healthy adults who took the drug in different forms and had their blood levels measured. The goal was to compare the formulations, not to treat any disease.

This study looked at how well two different autoinjectors deliver the drug mirikizumab into the bloodstream of healthy people. About 500 healthy adults received a single injection under the skin using either a standard 1-mL autoinjector or a newer 2-mL version. The goal was to se…

This study tested a new computer system that uses artificial intelligence to help doctors better diagnose and treat complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected information from 635 people, including healthy volunteers, to see if the …

This study looked at how moderate and severe liver impairment changes the way the body handles a single dose of the drug palovarotene. Researchers compared 31 participants with liver problems to healthy volunteers. The goal was to understand safety and drug levels in the blood, n…

This study looked at how the drug BI 1015550 is absorbed in people with and without kidney problems. 26 adults took a single tablet, and researchers measured drug levels in their blood over two weeks. The goal was to see if kidney issues change how the drug behaves, which helps d…

This early-stage study tested a single injection of a new drug called BI 3006337 in 80 healthy men. The main goal was to check if the drug is safe and how the body processes it. No treatment for any disease was given; this was purely a safety and drug-level study.

This study tested whether LED light can speed up skin healing. Ten healthy adults had small laser spots on their forearms, then received LED treatment. Researchers measured skin color and water loss to see if LED helped recovery. The goal was to find the best LED settings for fut…

This study looked at how two common antibiotics (amoxicillin and azithromycin) change the community of microbes living in healthy people, and whether those changes affect metabolism and the immune system. Over 100 healthy adults took antibiotics for a week or less, and researcher…

This study looked at how the drug MK-1084 (calderasib) moves through the body in people with moderate or severe kidney problems compared to healthy people. Researchers measured drug levels in the blood over time and checked for side effects. The goal was to understand if kidney f…

This study looked at how the experimental drug LY4064809 is absorbed and removed from the body in 10 healthy Chinese adults. Participants took the drug by mouth and were monitored for about 21 days. The goal was to measure drug levels in the blood and check for any safety issues.…

This study looked at how the drug MCI-186 moves through the body in people with severe liver damage compared to healthy people. Researchers gave a single dose to 12 adults and measured drug levels and side effects. The goal was to understand if liver problems change how the drug …

This early-stage study tested a new drug called BI 3034701 in 125 healthy men and people with overweight or obesity. The main goal was to see if different doses are safe and how the drug enters the blood. Participants received either the drug or a placebo as an injection under th…

This study looked at how different exercise programs affect physical performance, body composition, and mental readiness in tactical personnel like ROTC cadets. Researchers compared high-intensity functional training, traditional strength training, and a mix of both. The goal was…

This early-stage study tested a new drug called BI 706321 in 73 healthy men to see if it is safe and how the body processes it. Participants received single rising doses of the drug or a placebo. The goal was to gather safety information and measure drug levels in the blood, not …