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New drug interaction study in healthy men

NCT ID NCT02783040

First seen Apr 17, 2026

Summary

This early-phase study looked at how the experimental drug BI 425809 (iclepertin) changes the way the body processes four common medications: midazolam, warfarin, omeprazole, and digoxin. Thirteen healthy men took these drugs with and without BI 425809 to see if there were any interactions. The goal was to gather safety and dosing information, not to treat any disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • 1346.22.1 Boehringer Ingelheim Investigational Site

    Biberach, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Iclepertin (BI 425809)

What this could lead to

If successful, this study will help doctors understand how to safely combine BI 425809 with other common drugs.

What could go wrong

This is a very early, small study in healthy men, not patients. It only measures drug levels, not any treatment effect. Results may not apply to women or sick people.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.