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Ear zaps may alter pain signals, tiny study hints

NCT ID NCT07184190

Knowledge-focused Sponsor: University of Gran Rosario Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small pilot study tested whether stimulating a nerve in the ear (the auriculotemporal nerve) with mild electrical pulses can change how healthy volunteers process pain. Twelve people received two types of stimulation, and researchers measured pain thresholds and pain modulation. The goal was to see if this non-invasive technique could influence the body's pain signaling, which might one day lead to new pain treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcutaneous Auriculotemporal Nerve Stimulation (electrical stimulation device)
What this could lead to
If this works, it could point toward a new, non-invasive way to manage pain by stimulating a nerve in the ear.
What could go wrong
This is a very early pilot study with only 12 healthy people, not patients. It only tests short-term effects on pain processing, not real pain relief. Results may not apply to people with pain conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Sep 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects of both sexes, aged 18 to 35 years; * No symptoms or history of disease in the craniofacial region; * No symptoms of chronic pain in any body region. Exclusion Criteria: * History of surgery, trauma to the craniofacial region or cancer; * Systemic disease (e.g., rheumatic disease); * Neurological and/or psychiatric disorders; * Altered sensation (e.g., hipo or hypersensitivity); * Current pregnancy or menstrual cycle * Intake medication (e.g., centrally acting); * Prior experience with electrical stimulation treatment; * Intense physical activity, use of stimulants and/or analgesics in the previous 24 hours; * Acute sleep disruptions (e.g., recent sleep deprivation); * Inability to understand the informed consent document.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • Universidad del Gran Rosario

    Rosario, Santa Fe Province, S2134BZH, Argentina

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