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Gut hormone GLP-1: a key to intestinal blood flow?
NCT ID NCT01988545
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers are investigating how the natural gut hormone GLP-1 influences blood flow in the intestines and heart. The trial enrolls healthy volunteers who receive injections of GLP-1, a similar compound called exendin-4, or a saline placebo. Using ultrasound, the team measures changes in blood flow to understand GLP-1's role in circulation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- GLP-1 (a natural gut hormone), exendin-4 (a similar compound), or saline as a comparison
- What this could lead to
- If GLP-1 changes intestinal blood flow, it could help explain how this hormone affects digestion and blood circulation, possibly leading to new ways to manage gut or heart conditions.
- What could go wrong
- This is a very small study in healthy people, so the results may not apply to patients with disease. Injections can cause temporary side effects like nausea or changes in blood sugar.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
8 people
The number who actually took part.
- Started
-
Nov 2013
- Finished
-
Dec 2014
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy subjects Exclusion Criteria: * medical conditions
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Køge Hospital
Køge, State..., 4600, Denmark
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