Healthy volunteers help track new Drug's journey through the body
NCT ID NCT06687759
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how the experimental drug calderasib is absorbed, distributed, and removed from the body in 8 healthy adults. Participants took a single dose with a tiny radioactive tracer so researchers could measure the drug in blood, urine, and feces. The goal was to understand the drug's metabolism and clearance, not to treat any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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8 people
The number who actually took part.
- Started
-
Jun 2024
- Finished
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Aug 2024
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 55 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Key inclusion criteria include but are not limited to the following: * Is in good health based on medical history, physical examination,vital signs measurements, and electrocardiogram (ECG)s performed before randomization. * Has a body mass index (BMI) 18 to 32 kg/m2, inclusive, at screening Exclusion Criteria: The key exclusion criteria include but are not limited to the following: * Has a history of clinically significant endocrine, gastrointestinal (GI), cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases. * Has a history of cancer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fortea CRU Madison (Site 0001)
Madison, Wisconsin, 53704, United States
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