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Cycle timing could boost workout gains, new study suggests

NCT ID NCT06744517

Knowledge-focused Sponsor: University of Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study looks at whether doing sprint interval training during different phases of the menstrual cycle (follicular vs. luteal) changes how well your body adapts. Researchers will measure endurance performance and muscle changes in 24 healthy women who exercise regularly. The goal is to understand if cycle timing matters for training results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Jan 2025

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participating in 150 min of moderate-vigorous physical activity/week * VO2peak of 'good' or above based on American College of Sport Medicine (ACSM) normative values (greater than 35.0ml/kg/min for females and greater than 39ml/kg/min for males) * Body mass index (BMI) between 18-27 kg/m2 * Performing 2-4 structured exercise sessions/week. * Weight stable (within ± 2kg for at least 6 months) * Non-smoker * Females only: Menstrual cycle length of 27-35 days * Minimal menstrual cycle length variability (less than 3 days) * Ovulating monthly evidenced by a positive urinary luteinizing hormone surge * Blood progesterone concentration greater than 16 nmol/L. Exclusion Criteria: * Hormonal contraceptive use within the last 3 months * Polycystic ovarian syndrome (PCOS) or endometriosis * Failure to meet MC verification criteria. * Diagnosed with cardiovascular or metabolic disease, hyper- or hypogonadism, and/or PCOS * The use of medication for managing blood glucose or lipid metabolism * Current use of oral contraceptives or use within the last 3 months * Irregular menstrual cycles (\<27 days or \>35 days) * Pregnant or post-partum in the last 12 months, lactating or breast feeding within 3 months of the start of study, or menopausal * Recreational smoking tobacco * Inability to perform the study exercise protocols or follow the pre-trial dietary or physical activity controls * Taking medications affecting substrate metabolism (corticosteroids or nSAIDs) * Actively engaging in a low-carbohydrate diet (e.g., ketogenic, Atkins)

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • Goldring Centre for High Performance Sport

    Toronto, Ontario, M5S 2C9, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.