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New drug interaction study launches for methadone users

NCT ID NCT07528508

First seen Apr 21, 2026 · Last updated May 21, 2026 · Updated 7 times

Summary

This early-stage study looks at how a single dose of the experimental drug MK-8527 changes the way the body processes methadone. Researchers will measure methadone levels in the blood of 14 healthy adults over 24 hours. The goal is to understand if MK-8527 affects methadone breakdown, which could inform future dosing guidelines.

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