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Sitting linked to gut bacteria changes and polyp growth, study finds

NCT ID NCT07398820

Knowledge-focused Sponsor: Clínica Universidad de los Andes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 80 adults aged 40-60 to see if sitting for long periods slows down gut transit time and changes gut bacteria in ways that could lead to colon polyps. Participants wore activity monitors, ate blue muffins to track digestion time, and provided stool samples. The goal was to understand how lifestyle habits affect gut health and cancer risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

80 people

The number who actually took part.

Started

May 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients' recruitment will be conducted at Clínica Universidad de los Andes. Universe will include all subjects between 40-60 years of age who have undergone a colonoscopy during the previous year at Clínica Universidad de los Andes with a negative (control) or positive result with the presence of adenomatous polyp.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Both sexes. * 40-60 years of age. * Omnivorous diet. * Negative or positive colonoscopy result with adenomatous polyp during the last 12 months. Exclusion Criteria: * Antibiotic treatment during the previous month. * Daily use of aspirin. * Chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis). * Chronic constipation or diarrheic syndrome. * Autoimmune disease (such as celiac disease, type 1 diabetes, etc.). * HIV. * Food allergies. * Chronic use of laxatives. * Previous digestive surgery except appendicitis. * Familial adenomatous polyposis or Lynch disease. * Obesity (BMI\>30) and/or type 2 diabetes mellitus.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal neoplasm Motor Activity Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenoma Healthy

Contacts and locations

Locations

  • Clínica Universidad de los Andes

    Las Condes, Santiago Metropolitan, 26183000, Chile

More trials for these conditions

Other studies related to the condition(s) this trial covers.