HEALTHY

This study tested a drug called ciraparantag to see if it could quickly reverse the effects of blood thinners in healthy adults. The trial was stopped early, and only 41 people participated. The main goal was to measure how well the drug restored normal blood clotting within an h…

This small pilot study tested whether a cream containing stem cell secretome and licorice root extract could safely improve vaginal laxity (looseness) in women aged 40 to 55 in Malaysia. Over 5 weeks, researchers measured changes in vaginal tightness using a questionnaire and a p…

This study tested a new cooling device to see if it could reduce pain during a skin treatment called radio-frequency microneedling. Six healthy women took part, and researchers measured their pain levels after different cooling times. The study was stopped early, so results are l…

This early-stage study aimed to test the safety of a new drug called LY3872386 in healthy volunteers and people with atopic dermatitis (eczema). The study was terminated early, so no meaningful results are available. Only 18 participants were planned, and the drug's effects on ec…

This early-stage study tested an experimental drug (PF-07899895) in 37 healthy adults to see if it was safe and how the body processes it. Participants received either the drug or a placebo in different dosing schedules. The study was terminated early, so results are limited.

This early-stage study looked at how healthy men absorb, break down, and eliminate the experimental drug BI 1839100. In one part, participants took the drug by mouth and researchers measured how much came out in urine and stool. In another part, the drug was given both by mouth a…

This early-stage study tested the safety and how the body handles a new drug called MT-6345 in 52 healthy adults. The goal was to see what side effects occur and how the drug moves through the body. Since it was only a safety study in healthy people, there was no treatment for an…

This study looks at how healthy men absorb, break down, and eliminate a drug called BI 1819479. It has two parts: one tracks the drug's radioactivity in urine and stool, and the other compares a tablet form to a low-dose injection. The goal is to understand the drug's behavior in…

This early-stage study aimed to check the safety and side effects of a new drug called LY3463251 in healthy and overweight adults. Participants received either the drug or a placebo under the skin. The study was stopped early, and no results are available.

This study looked at how changing when you eat affects blood sugar, body temperature, and sleep in people with prediabetes, type 2 diabetes, and healthy adults. Researchers used wearable devices to track these measures over time. The goal was to better understand the body's respo…

This early-stage study tested a single dose of the experimental drug BI 1569912 in 68 healthy men to see if it is safe and how the body processes it. The study also looked at how food affects the drug's absorption. The trial was terminated early, so results are limited.

This early study aimed to see if insulin given as a nasal spray can reach the brain and spinal fluid. Only 2 healthy adults took part before the study was stopped. Researchers collected fluid samples before and after a single dose to measure insulin levels. The results will help …

This study aimed to see if a mind-body medicine training program could help parole staff feel less stressed, anxious, and burned out, while increasing their resilience and empathy. Twenty-seven staff members attended a 4-day training, a 2-day practicum, and group sessions, and fi…

This study tested a new way to take pictures of the lungs and brain using MRI and a special gas called xenon. Healthy adults aged 18 to 75 breathed in the gas and then had an MRI scan. The goal was to see if this method could produce clear images without using X-rays or radiation…

This early-stage study aimed to check the safety and how the body handles multiple doses of an experimental drug called BI 3731579. It involved 30 healthy adults aged 18 to 55 who took the drug or a placebo daily for 15 days. The trial was terminated early, so results are limited…

This study looked at how moderate versus high intensity exercise programs affect the way healthy, sedentary adults process pain. Researchers measured pain sensitivity and the body's natural pain control systems. The goal was to find the best exercise prescription for reducing pai…

This study looked at why exercise training improves blood vessel function less in some people with COPD compared to healthy individuals. Researchers measured blood vessel health and related biological markers in 69 participants (COPD patients and healthy volunteers) before and af…

This study looked at how running a marathon on flat roads compares to running a trail race with hills and uneven ground. Researchers measured muscle strength in the legs before and after each race to see which type causes more fatigue and how quickly runners recover. The goal was…

This study tested whether a gel made with tiny silver particles could kill bacteria on hands better than a common alcohol-based hand gel. Healthy adults had their hands covered with a harmless bacteria, then used one of the gels. The study was stopped early and only 22 people too…

This study looked at how a standardized ashwagandha supplement is absorbed and processed in healthy adults aged 65 and older. Researchers measured levels of active compounds in the blood after taking the supplement. The goal was to gather safety and processing information, not to…

This study tested whether the experimental medicine REM0045392 is safe and how food affects its absorption. It involved 19 healthy adults, including older participants. The study was stopped early, and no treatment benefits were measured.

This early-stage study tested whether the experimental drug PF-07314470 is safe in healthy adults and how the body absorbs and removes it. The trial was stopped early by the sponsor. It involved 23 healthy volunteers aged 18 to 55 who received either the drug or a placebo by inje…

This study aimed to see how two malaria medications, artemether-lumefantrine and amodiaquine, interact in healthy adults. It enrolled 8 healthy Thai volunteers and measured drug levels in the blood. The study was terminated early, so results are limited. It does not offer any tre…

This study looked at how safe a new drug, BI 706321, is and how it moves through the body in healthy Japanese and Chinese men. The trial was stopped early. It involved 48 participants and was designed to gather safety information, not to treat any disease.

This early-stage study aimed to check the safety and how the body handles a new experimental drug called BI 3009947 in healthy men. It also compared two different pill versions of the drug and looked at how food affects one of them. The study was stopped early and involved 40 par…

This study tested a new, taste-masked powder form of the antibiotic delafloxacin to see if it works as well as the current tablet. Sixteen healthy adults took either the powder or the tablet, and researchers measured how much of the drug got into their blood. The goal was to make…

This study aimed to compare how the immune system responds to two different seasonal flu vaccines, one with an adjuvant (Fluad) and one without (Afluria), in healthy adults aged 18-49 who hadn't had a flu shot in at least three years. Only 2 people enrolled before the study was t…

This study looked at whether oxytocin, a natural hormone, can reduce pain when given through an IV. It included 7 people—some healthy and some with severe knee arthritis. Researchers measured pain from a heated skin patch to see how oxytocin changes pain perception.

This study aimed to check the safety and side effects of an experimental drug called LY3526318 in healthy adults. It was a Phase 1 trial with two parts, lasting up to 51 days total. The study was terminated early, and no results are available. It involved 76 healthy participants …