HEALTHY

This study tests a new vaccine (V540A) designed to protect against more types of HPV, a virus that can cause cancer. It includes the 9 types covered by the current vaccine plus additional ones. About 525 healthy females aged 16 to 26 will receive either the new or current vaccine…

This study looks at whether eating 50 grams of walnuts every day for 24 weeks can improve brain blood flow and insulin sensitivity in adults aged 45-75 with abdominal obesity. Participants will have MRI scans and thinking tests before and after the walnut or no-walnut period. The…

This study explores whether a non-invasive light-based device (SR-NIRS) can measure blood flow and oxygen levels in the testicles of children. It includes healthy boys and those with sudden scrotal pain to see if the device can help tell if testicular torsion is present. The goal…

This study checks if a new portable device can accurately measure ankle looseness in people with and without ankle problems. Researchers will test it on 62 young adults, including healthy individuals, those with a past sprain, and those with chronic ankle instability. The goal is…

This study tests whether taking a special probiotic (a type of good bacteria) can help healthy adults sleep better and feel less stressed during short trips. Sixty volunteers will take either the probiotic or a placebo pill for a short time while traveling. Researchers will track…

This study looks at whether a substance from broccoli (glucoraphanin) can help muscles heal faster after intense exercise. Seventeen healthy adults who don't currently do resistance training will take either the broccoli supplement or a placebo for a week, then do a special arm e…

This study looks at whether a product called Phaseolean can help control blood sugar after eating carbohydrate-rich meals. It involves 12 healthy adults aged 18 to 45 with normal blood sugar and weight. Participants will eat test meals and have their blood sugar and feelings of f…

This study looks at whether playing alternative sports (korfball, flag football, kin-ball, ultimate frisbee) in gym class can improve physical fitness, motor skills, and enjoyment for 210 healthy primary school students. Over 8 weeks, one group will play these sports while the ot…

This study tests a supplement called Prosman™, made from plum extract, for men aged 40-60 with mild-to-moderate prostate enlargement symptoms. 38 men will take either Prosman™ or a placebo daily for 8 weeks. Researchers will measure changes in urinary symptoms, hormone levels, an…

This study tests whether a daily collagen peptide supplement called AP-Brain can improve attention, focus, and memory in adults aged 35-70 who are stressed but otherwise healthy. Participants will take either a higher or lower dose for 56 days and complete computer tasks and surv…

This study tests whether a special vibrating device can reduce pain and anxiety in children aged 6 to 14 during dental injections. Each child will try both the device and a manual vibration method on separate visits to compare which works better. The goal is to make dental visits…

This study tests whether a cosmetic product (RV2666C) helps heal skin after a laser treatment that removes the top layer. About 24 adults with darker skin tones (types IV to VI) will apply the product daily for 18 days. Researchers will measure wound healing, redness, pigmentatio…

This study explores whether placebo suggestions that match a person's motivational style (how they approach goals) can change their experience of pain. Sixty healthy adults will receive heat pulses and rate their pain after receiving suggestions tailored to their style. The goal …

This early-stage study tests a new drug, KR23343, in 92 healthy adults aged 18 to 45. The goal is to check if the drug is safe and how the body processes it, including the effect of food. Participants will receive either the drug or a placebo, and some will take it daily for 10 d…

This study looks at how different types of light affect attention and learning in college students. Researchers at Michigan State University will have 300 healthy undergraduates wear special light-enriched glasses in class. They will measure how fast and accurately students compl…

This study looks at how taking a new combination diabetes pill with or without food changes the way the body absorbs the medication. It involves 28 healthy adults in Thailand who will take the pill once while fasting and once after a meal. The goal is to understand food's effect …

This study looks at whether drinking enough plain water every day for 4 weeks can change how thirsty healthy young adults feel. Researchers will measure thirst ratings and body chemistry in 120 participants who usually drink less than 1 liter of plain water daily. The goal is to …

This early-stage study tests a single dose of a new drug, SSS67, in 52 healthy adults to see if it is safe and how the body processes it. Participants receive either the drug or a placebo by IV, and researchers monitor side effects, drug levels, and immune responses. No treatment…

This study looks at how the body makes new sugar from fat and blood molecules in people with and without type 2 diabetes. Researchers will give special tracers and take blood samples to track this process. The goal is to find new ways to lower blood sugar more effectively. About …

This early-stage study is testing a new drug called BI 3814916 in 136 healthy adults aged 18 to 65. The main goal is to see if the drug is safe and how the body processes it. Participants will receive either the drug or a placebo, and no direct health benefit is expected.

This study will test whether a digital chatbot can help 1,000 parents and caregivers in the UK better recognize false information about routine childhood vaccines. Participants will interact with the chatbot and then be tested on their ability to tell true from false vaccine stat…

This study looks at how a 16-week moderate-to-vigorous physical activity program affects physical fitness and gut bacteria in healthy school-aged children. About 113 kids will be randomly assigned to either an exercise group or a control group. The goal is to see if exercise can …

This study looks at whether using artificial intelligence (AI) in case discussions helps midwifery students become more comfortable and skilled with AI tools. About 81 third- and fourth-year students will take part. The goal is to see if AI can boost their clinical thinking and p…

This study tests whether a virtual reality (VR) program can help nursing students improve how they counsel day surgery patients. Sixty nursing students will take part; half will use the VR program alongside their regular classes, and half will only have regular classes. The main …

This study looks at how two different versions of gecacitinib hydrochloride tablets are absorbed and processed by the body in healthy adults. About 64 participants aged 18 to 45 will take a single dose under fasting conditions. The goal is to compare the drug levels in the blood,…

This study looks at how different forms of chickpeas—like whole, pureed (hummus), or as pasta—change the way your body uses energy. Researchers will measure fat, carbohydrate, and protein burning in 204 healthy adults over 12 weeks. The goal is to understand if processing affects…

This study looks at how a new drug called eltrekibart is absorbed when injected under the skin. It involves 60 healthy adults who will receive a single dose and be monitored for about 17 weeks. The goal is to measure drug levels in the blood and check for side effects, not to tre…

This early-stage study looks at how eating a high-fat or low-fat meal changes the way a new drug, FWD1802, is processed in the body. It involves 18 healthy Chinese adults who take the drug once under different meal conditions. The goal is to understand if food affects drug levels…

This study tests whether a single 40-minute session of exergaming-based seated Tai Chi can improve memory and thinking skills in healthy young (18-30) and older (60-75) adults. Participants will try both the Tai Chi game and a simple stretching routine on separate days, while the…

This study looks at whether a program led by senior nursing students—using videos filmed in real hospital settings, interactive sessions, and a guided tour—can help first-year nursing students feel less overwhelmed and adapt better during their first time in a clinical environmen…

This study looks at whether showing people a real-time visual display of their swallowing pressure helps them perform swallowing exercises more effectively. Fifty healthy adults aged 18-40 will swallow with and without this visual feedback while a thin tube measures their throat …

This study looks at how a new curcumin capsule is absorbed in the body compared to a similar product. It involves 12 healthy adults who take the capsules after a meal. Blood tests measure the amount of curcumin in the body over time. The goal is to see if the new capsule delivers…

This study looks at how lifestyle factors like physical activity, diet, sleep, and stress affect heart and mental health in healthy adults aged 40-65 living in the Meuse-Rhine region. Researchers will track 1,000 participants for six months, using wearable devices and questionnai…

This study aims to find the best way to collect and handle stool samples for analyzing gut bacteria. Researchers will compare different collection methods to see which one gives the most accurate results. Ten healthy adults will provide samples using various devices. The goal is …

This study looks at how to fairly compare muscle strength among healthy women of different sizes. Researchers will test trunk, hip, and knee strength in 112 women and see whether using body weight or body mass index (BMI) gives more consistent results. The goal is to improve how …

This study looks at how a structured physiotherapy program after cosmetic leg-lengthening surgery affects daily movement and physical function. It will involve 54 adults aged 18-45 who have the surgery. Researchers will measure changes in strength, walking, pain, and independence…

This study looks at whether teaching nursing students with AI tools helps them think more critically than standard case-based lessons. About 400 students will be split into two groups: one gets AI-assisted training, the other gets traditional teaching. Researchers will measure ch…

This study tests whether a mobile app that uses AI and game-like features can help young adults (ages 18-24) who face food insecurity make healthier food choices. About 114 UC Davis students will use either a basic food-tracking app or a version with extra nudges and rewards for …

This study looks at how the brain's map of the back changes in people with long-term low back pain compared to healthy volunteers. Participants will lie on a special surface during an MRI scan to see how their brain reacts. The goal is to find brain patterns that could lead to be…

This study looks at how different liquid versions of the drug osivelotor taste and how well they get into the blood compared to a tablet. It also checks if taking the drug with food or an antacid changes absorption. About 52 healthy adults aged 18 to 65 will take part. The goal i…

This study will test a new ultrasound device that creates 4D (3D + real-time) images of the upper airway, head, and neck. Researchers want to see if this device can show areas that regular ultrasound cannot, like behind the jaw or windpipe. About 100 healthy adults will lie still…

This early-stage study looks at how a single dose of the experimental drug MK-8527 changes the way the body processes methadone. Researchers will measure methadone levels in the blood of 14 healthy adults over 24 hours. The goal is to understand if MK-8527 affects methadone break…

This study tests a new AI chatbot designed to help parents resist false information about vaccines. Researchers will enroll 5,000 parents from five European countries. The chatbot teaches parents to recognize common tricks used in vaccine misinformation. The goal is to see if the…

This early-stage study in 24 healthy adults aims to understand how different versions of the experimental medicine PF-08049820 are absorbed and cleared from the body. Participants will take the medicine under various conditions—with or without food, and with or without a stomach-…

This study tests if a simple camera can track how movement changes during large exercises like reaching and stepping. Healthy adults will do six exercises while a camera records them. The goal is to see if the camera can detect when movements get smaller over time, which could he…

This study looks at how beta-cells (the cells that make insulin) respond to growth hormone in people with prediabetes. Researchers will compare two groups: those with impaired fasting glucose and those with impaired glucose tolerance. The goal is to better understand what leads t…

This study looks at whether a single dose of ulonivirine changes how the body processes methadone. Fourteen healthy adults who are already on a stable methadone program will take methadone alone and then with ulonivirine. The goal is to measure drug levels in the blood to see if …

This study checks if a special camera that looks at tiny blood vessels under the tongue can give consistent results. It will include 200 people: healthy volunteers and critically ill patients in the ICU. Researchers will take multiple measurements to see if the method is reliable…

This study looks at a new idea called Satiety Per Calorie (SPC) — how full a food makes you feel for each calorie it contains. Researchers will measure how much 40 healthy men eat after being given different foods. The goal is to understand why some foods lead to overeating and h…

This study looks at how inflammation in the tooth's inner tissue (pulp) differs between people with painful pulpitis and healthy individuals. Researchers will measure specific substances in saliva, gum fluid, and pulp samples to see if they can serve as simple, non-invasive marke…

This study will test a standard tooth-bleaching procedure on 10 healthy adults to see exactly how tooth color changes. Researchers will use a special tool to measure whiteness and color shifts before and after treatment. The goal is to better understand which color changes matter…

This early-stage study will give verducatib pills daily for 4 weeks to 12 healthy Chinese adults aged 18-55. The goal is to measure how the drug moves through the body and check for any side effects. Participants will not receive any direct medical benefit, but results will help …

This study looks at whether taking aspirin at specific times of day can prevent the blood pressure increases that sometimes happen with the pain reliever celecoxib. Researchers will measure blood pressure in 60 healthy adults over time. The goal is to understand how timing affect…

This study looks at how mood, behavior, and brain activity change in young adults (ages 18-21) who use cannabis. Researchers will use brain scans and questionnaires to understand why some people respond differently to the same drug. The goal is to learn more about individual diff…

This study looks at whether the natural daily rise and fall of cortisol (a stress hormone) is reflected in the fluid around eggs in women undergoing IVF. Researchers will collect blood and follicular fluid samples at 8 a.m. and 8 p.m. from 20 healthy women aged 18-35. The goal is…

This study looks at whether providing free school meals to Danish children aged 10 to 15 can improve their health, well-being, and learning. About 3,200 kids will be followed for 1.5 years, with some receiving free meals and others not. Researchers will measure changes in quality…

This study looks at whether moving nurses between different heart-care units every two months helps them learn more and feel less burned out. About 86 nurses will take part, with some rotating and others staying in place. Researchers will measure skills, job satisfaction, and wor…

This early-stage study tests a new medicine, PF-08065010, in 100 healthy adults aged 18-65 to check its safety and how the body processes it. Participants receive either the drug or a placebo as a shot or IV, with some getting a single dose and others monthly doses for 3 months. …

This early-stage study tests a new Pfizer medicine (PF-08057418) in 8 healthy adults to see if it is safe and how the body processes it. Participants receive the drug once a week for 5 weeks as a solution or tablet. The study is not yet recruiting and focuses on safety and drug l…

This study compares two similar oral drugs in 60 healthy adults aged 19 to 64. Participants will take a single dose of each drug at different times to measure how the body processes them and to check for side effects. The goal is to gather information, not to treat any disease.

This study will test a non-invasive technique called focused ultrasound on the brains of 25 healthy adults aged 18-55. Researchers want to see how it changes brain signals and chemical levels. The goal is to understand how the method works and if it is safe, not to treat any dise…

This study compares two brain stimulation methods—standard electrical stimulation and a newer magnetic version—to see which better improves working memory. About 102 healthy adults will perform memory tasks while receiving stimulation. The goal is to find a more comfortable and e…

This early-stage study tests an experimental drug called LY4302814 in 150 healthy adults to see if it is safe and how the body handles it. Participants will receive either the drug or a placebo and stay overnight at a clinic for up to 9 days. The study lasts about 6 months and do…

This study looks at whether a computer-based training program can improve cognitive flexibility—the ability to switch between tasks or strategies. Researchers will enroll 225 healthy adults aged 18-29 and use brain scans and thinking tests to measure changes. The goal is to under…

This early-stage study tests whether a single injection of HS-20136-2 is safe and tolerable in healthy adults aged 18-65. About 38 participants will receive either the drug or a placebo, and researchers will monitor for side effects and how the drug moves through the body. No tre…

This study tests a new type of eye scanner (PS-OCT) to see if it can take clearer pictures of the retina's nerve fibers. About 20 healthy adults aged 18-85 will have their eyes imaged. The goal is to measure how well the device works, not to treat any disease.

This small pilot study looks at how a new probiotic supplement (BEO001) changes gene activity and sugar patterns in the small intestine of 8 healthy adults. Participants take the probiotic alone, with fiber, or a placebo, and provide gut tissue samples via a scope the next day. T…

This study looks at whether different types of exercise—like high-intensity workouts and Tai Chi—can improve memory, focus, and flexibility in thinking, while also reducing stress. It involves 120 healthy first-year university students in Chile. Participants will be assigned to o…

This study will test a new device that uses machine learning to measure foot pressure and foot area. Researchers want to see if it works as well as current standard tools. 150 healthy adults will take part. The goal is to improve how foot pressure is measured, which could help wi…

This study checks if taking a probiotic capsule every day for 15 days causes any stomach problems in healthy adults. Twenty volunteers will take the probiotic and report any side effects like bloating or discomfort. The goal is simply to see if the probiotic is safe, not to treat…

This study looks at how two types of laser therapy (high-intensity and low-level) affect nerve function in healthy adults aged 18-30. Participants will be randomly placed into one of three groups: high-level laser, low-level laser, or a sham (placebo) group. Over 3 weeks, they wi…

This study looks at how non-invasive brain stimulation (rTMS) affects two different areas of the cerebellum—one linked to movement and one linked to thinking. Forty healthy adults will receive either stimulating, inhibiting, or fake (placebo) stimulation in random order. The goal…