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Sniffing out cancer: new breath test could spot colon cancer before it spreads

NCT ID NCT07620743

Diagnosis Sponsor: Beijing University of Chinese Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new, non-invasive method to detect colorectal cancer and precancerous growths by analyzing odors from breath and intestinal gas. About 453 participants—including people with colorectal cancer, precancerous lesions, and healthy volunteers—will provide samples and allow researchers to compare the odor test results with standard colonoscopy findings. The goal is to see if this simple, painless test can catch the disease early, potentially replacing more invasive procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 453 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of three groups recruited primarily from Beijing University of Chinese Medicine, Dongfang Hospital： Patients with histopathologically confirmed colorectal cancer (TNM stage I-IV). Patients with histopathologically confirmed precancerous lesions (e.g., colorectal adenomas, sessile serrated lesions). Healthy controls with no abnormalities on colonoscopy within the past year and no history of colorectal cancer or other malignancies. Participants will be adults aged 18 to 85 years. Healthy controls will be recruited from the same hospital settings and matched for key demographic factors (age, sex, BMI) and lifestyle habits to minimize confounding.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 85 years, male or female * Histopathologically or cytologically confirmed colon or rectal cancer (TNM stage I-IV) for colorectal cancer group * Histopathologically confirmed adenomatous polyps, sessile serrated lesions, traditional serrated adenomas, or other precancerous lesions for precancerous lesion group * No abnormality on colonoscopy within the past year; no personal history of colorectal cancer or other malignancies; no chronic diseases requiring long-term treatment for healthy control group * Willing and able to provide signed informed consent Exclusion Criteria: * Hereditary colorectal cancer syndromes (e.g., familial adenomatous polyposis, hereditary non-polyposis colorectal cancer) * Autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis) * Severe cardiovascular, respiratory, or urinary system diseases * Other primary malignant tumors * Hematological diseases * Unable to comply with study procedures (e.g., sample collection or questionnaires) * Planning to become pregnant, pregnant, or breastfeeding * Suspected or confirmed alcohol or drug abuse * Known allergy to any drug used for colorectal cancer treatment * Participation in another interventional drug clinical trial within the past month * Any other condition that, in the investigator's judgment, makes the participant unsuitable for the study

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal carcinoma precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRC Healthy Precancerous condition

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing University of Chinese Medicine

    Beijing, Beijing Municipality, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.