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Brain training study seeks to boost mental flexibility in healthy young adults

NCT ID NCT07556250

Knowledge-focused Sponsor: Nanyang Technological University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether cognitive flexibility—the ability to switch between different ways of thinking—can be improved through targeted training. Researchers will enroll 225 healthy adults aged 18-29 and have them complete up to 12 sessions of structure learning or set-shifting tasks over 12 days. The goal is to see if this training leads to lasting improvements in thinking skills and changes in brain activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Structure Learning Training (behavioral intervention)
What this could lead to
If successful, this could point toward new ways to improve mental flexibility and learning skills in healthy people.
What could go wrong
This is an early-stage study in healthy volunteers, not a treatment trial. Results may not apply to clinical populations, and training effects may be small or not last.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 225 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 29 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy volunteer (male of female) between 18 and 29 years who gave written informed consent to participate Exclusion Criteria: * Current and/or prior history of learning disabilities * Current and/or prior history of neurological disorder * Current and/or prior history of psychiatric disorder * Current and/or prior history of cardiovascular disorder * Predominantly left-handed * Contraindications for MRI (e.g., pacemakers, implanted pumps, metal objects in the body) * Claustrophobic * Pregnancy (females) * Lactation (females) * Pronounced visual or auditory impairments

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre for Lifelong Learning and Individualised Cognition (CLIC), Nanyang Technological University

    Singapore, 637335, Singapore

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