Could an arthritis drug ease tough schizophrenia symptoms?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Screening * Age range of 18-64 * Schizophrenia Group: Meet meet DSM 5 criteria for schizophrenia or schizoaffective disorder * Healthy Control Group: Does NOT meet DSM 5 criteria for schizophrenia or schizoaffective disorder, bipolar disorder, or major depressive disorder. Exclusion Criteria: Screening * Known current active infection, or taking an immunosuppressive medications (e.g. oral scheduled corticosteroids, chemotherapy or transplantation or HIV/AIDs associated drugs), or the scheduled use of anti-inflammatory medications, including NSAIDs (e.g. ibuprofen, celecoxib, or naproxen) or aspirin \> 81 mg on a daily basis will be excluded. * Score of less than 10/12 on the ESC Inclusion Criteria: Clinical Trial * Age range of 18-64 * Meet meet DSM 5 criteria for schizophrenia or schizoaffective disorder * Personal and Social Performance (PSP) Scale score of ≤70. * Treated with the same antipsychotic for at least 30 days and having received a constant therapeutic dose for at least 15 days prior to study entry * One test in the past of elevated AGA IgG antibodies (AGA IgG \> 15) Exclusion Criteria: Clinical Trial * Current infection, including HIV, and Hepatitis C (blood draw) or tuberculosis (TB\*); or an organic brain disorder or medical condition, whose pathology or treatment could alter the presentation or treatment of schizophrenia or significantly increase the risk associated with the proposed treatment protocol. * Currently taking immunosuppressive medications (e.g. oral scheduled corticosteroids, chemotherapy or transplantation or HIV/AIDs associated drugs); or the scheduled use of anti-inflammatory medications, including NSAIDs (e.g. ibuprofen, celecoxib, or naproxen) or aspirin \> 81 mg on a daily basis will be excluded. The use of PRN anti-inflammatory agents will be allowed * Score of less than 10/12 on the ESC