Why do some COPD patients get less benefit from exercise? new study investigates
NCT ID NCT03774238
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at why exercise training improves blood vessel function less in some people with COPD than in healthy individuals. Researchers measured blood vessel health before and after a 4-week exercise program in 69 participants, including COPD patients and healthy volunteers. The goal was to find biological and functional factors that explain these differences, which could help personalize rehabilitation programs.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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69 people
The number who actually took part.
- Started
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Feb 2019
- Finished
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Nov 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: A/ COPD patients * age between 35 and 85 years old * spirometry showing an FEV1/VC \< lower limit of normal * with an indication for a pulmonary rehabilitation program * written and informed consent for this study signed by the patient B/ Healthy subjects * age between 35 and 85 years old * no cardiovascular or respiratory disease * normal spirometry Exclusion Criteria: * Unstabilized comorbidity * Subject in a period of exclusion relative to another protocol * Major protected by law * Subject participating in another research protocol * Subject not affiliated to a social security scheme * Pregnant or lactating woman * Patient deprived of freedom by court or administrative order
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Montpellier and CHU Nimes
Montpellier, 34295, France
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University Hospital, Paris
Paris, 75015, France
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Other studies related to the condition(s) this trial covers.
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