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Can salt intake explain racial differences in bone and blood pressure health?

NCT ID NCT05537857

Knowledge-focused Sponsor: San Diego State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Sep 21, 2026 · Updated 1 time

Summary

This study investigates whether people of different racial and ethnic backgrounds process calcium and sodium differently when eating high versus low amounts of salt. Healthy adults who are Black, White, Hispanic, or Asian will follow controlled diets with either typical Western salt levels or lower recommended levels, and researchers will measure how much calcium their bodies absorb and how much calcium and sodium they excrete. The goal is to understand if current dietary advice, which often promotes milk, may need to be personalized to better protect against conditions like osteoporosis and high blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Controlled diets with high and low salt content, using lactose-free milk as a calcium source
What this could lead to
If successful, this could help tailor dietary salt and calcium recommendations to different racial and ethnic groups, potentially reducing risks of osteoporosis and hypertension.
What could go wrong
This is an early-stage, small study (66 participants) that measures short-term metabolic responses, not long-term health outcomes. Results may not apply to everyone or predict real-world disease risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Mar 2023

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy adults age 18-50 years, but not postmenopausal * 3 of 4 grandparents identified as one of four major racial/ethnic groups * BMI between 18.5 and 30 AND waist circumference less than or equal to 88 cm for females and 102 cm for males * No allergy to lactose-free milk. Exclusion Criteria: * Taking vasoactive or calcium metabolism-altering medications (statins, antihypertensives, aspirin, steroids, bisphosphonates, thiazide diuretics, hormone replacement therapy, and antidepressants) * Had bone fracture within the past 6 months * Diabetes * Cance * Liver disease * Gastrointestinal disease (e.g.: Crohn's disease, irritable bowel syndrome, malabsorption syndrome) * Decreased kidney function * Smoking within the past 12 months before the study. * Habitually consumption \> 1000 mg Ca/d from food or supplements.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • San Diego State University

    San Diego, California, 92182, United States

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