Parkinson's patients help unlock the Brain's inner clock
NCT ID NCT02126475
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how Parkinson's disease changes the way people perceive time. Researchers measured eye movements in 40 participants (Parkinson's patients and healthy volunteers) to understand the role of dopamine in timing. Patients were tested both on and off their medication to see how dopamine affects their ability to anticipate events. The goal was to learn more about how the brain processes time, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
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Apr 2014
- Finished
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Feb 2016
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy volunteers and Parkinson patients, non fluctuent
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy volunteers : * Men or women, age: 18 to 65 years old * Subject affiliated to a national insurance scheme * Informed consent of the study signed * Normal neurological exam 2. Patients: * Men or women, age: 18 to 65 years old * Subject affiliated to a national insurance scheme * Informed consent of the study signed * Idiopathic Parkinson disease, UKPDSBB criteria (Hughes, Ben-Shlomo, Daniel, \& Lees, 1992; Hughes, Daniel, Kilford, \& Lees, 1992; Hughes, Daniel, \& Lees, 2001) * Non fluctuant patients * Patients treated by L-Dopa +/- other anti-Parkinsonian's, stable dose for 30 days Exclusion Criteria: * Cognitive or behavioural disorder * Severe psychiatric symptomatology and psychotropic drug use * Subject non-affiliated to a national insurance scheme * No signature of the Informed consent of the study * Subject freedom-deprived by court or administrative order
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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ICM
Paris, 75013, France
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ICM-IHU
Paris, 75013, France
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