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Healthy volunteers help uncover drug interaction risks

NCT ID NCT05338476

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study looked at how a cancer drug called selpercatinib changes the way the body processes midazolam, a sedative. Sixteen healthy adults took both drugs, and researchers measured drug levels in the blood. The goal was to see if selpercatinib affects how fast midazolam is absorbed and cleared, which helps doctors adjust doses safely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Celerion

    Tempe, Arizona, 85283, United States

Conditions

Explore the condition pages connected to this study.