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Scientists uncover how gentle exercise with blood flow cuffs changes pain perception

NCT ID NCT07122011

Knowledge-focused Sponsor: University of Gran Rosario Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a single session of low-intensity exercise with blood flow restriction (BFR) changes pain perception in 20 healthy young adults. Researchers measured pain thresholds and the body's natural pain-fighting system before and after the exercise. The goal was to better understand the nervous system's role in exercise-induced pain relief, which could guide future pain rehabilitation research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Aug 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Asymptomatic at the time of evaluation. * Able to provide written informed consent. * Available to attend a single evaluation and intervention session at the research center. Exclusion Criteria: * Bilateral knee symptoms or suspected patellar tendinopathy. * Increased symptoms with dynamic loading. * Neurological disorders. * Inflammatory rheumatic diseases. * Cardiac diseases. * Any surgery within the last 3 months. * Pregnancy. * Alcohol consumption on the day of participation. * Hypertension (systolic blood pressure ≥140 mmHg). * History of deep vein thrombosis. * History of endothelial dysfunction. * Peripheral vascular disease. * Diabetes. * Active infection. * Spinal or referred pain. * Previous experience with blood flow restriction (BFR) training. * Overweight or obesity.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • University Center for Assistance, Teaching and Research (CUADI)

    Rosario, Santa Fe Province, 2000, Argentina

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