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Hydrogen gas may alter metabolism during cycling, small study suggests

NCT ID NCT06951789

Knowledge-focused Sponsor: Palacky University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether inhaling hydrogen gas affects how the body uses fuel during light exercise. Twenty healthy women rode a stationary bike for 30 minutes while breathing either hydrogen or a placebo. Researchers measured metabolism, heart rate, and perceived effort. The goal was to see if hydrogen could shift fuel usage, which might have implications for exercise science.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
molecular hydrogen gas
What this could lead to
If it works, this could point toward a way to improve exercise efficiency or recovery using hydrogen inhalation.
What could go wrong
This is a very small, early study in healthy volunteers, not patients. The effects may be tiny or not meaningful for real-world performance or health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

May 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Free of major diseases. * Signed informed consent. Exclusion Criteria: * Acute conditions contraindicating laboratory testing of exercise. * Cardiorespiratory disease. * Pharmacotherapy affecting metabolism. * Musculoskeletal problems.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy Respiratory quotient measurement

Contacts and locations

Locations

  • Palacky University, Faculty of Physical Culture

    Olomouc, Czech Republic, 77111, Czechia

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