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AI takes on HPV vaccine myths: can a chatbot outsmart misinformation?

NCT ID NCT06702423

Prevention Sponsor: The University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether an AI-powered chatbot can improve health literacy about the HPV vaccine among Japanese caregivers of unvaccinated daughters aged 12–18. Participants will either interact with the chatbot or read a standard government leaflet, then complete surveys to measure changes in knowledge and vaccination decisions. The goal is to see if a digital tool can more effectively counter misinformation than traditional written materials.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
An AI-powered chatbot delivering tailored HPV vaccination information
What this could lead to
If effective, this chatbot could become a scalable tool to counter vaccine misinformation and improve HPV vaccination rates among young girls in Japan.
What could go wrong
The trial measures knowledge and decision-making, not actual vaccination uptake. The chatbot's impact may be limited if caregivers already hold strong beliefs or lack internet access.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

804 people

The number who actually took part.

Started

Nov 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A nationally representative sample of female caregivers with daughters aged 12-18 who have not received any HPV vaccine. * Those who have access to a smartphone or computer with internet connectivity to interact with experiment materials (chatbot or online leaflet). * Those who provide informed consent and agree to participate in the study. Exclusion Criteria: * Those who need help reading through the participant information sheet, providing consent online, accessing experiment materials (chatbot or online leaflet), or answering surveys will be excluded. This may include people who do not have access to an online environment or people with severe cognitive impairments who cannot interact with the experiment materials. Also, those who have participated or are participating in similar studies regarding vaccination or experiments that utilize chatbots will be excluded.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • London School of Hygiene and Tropical Medicine

    London, United Kingdom

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