Kidney health may change how body handles cancer drug

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For all participants: * Body mass index (BMI) ≥ 18.0 and ≤ 40.0 kilograms per meter squared (kg/m²) and had a minimum weight of at least 50 kg at screening * Have normal blood pressure, pulse rate, electrocardiogram (ECG), and blood and urine laboratory test results that are acceptable for the study * Female of non childbearing potential: must have undergone sterilization procedures at least 6 months prior to the Screening * Males who are capable of fathering a child must agree to use contraception from the time of the dose administration through 6 months after the last dose For renal participants: * Participant has stable renal disease status and function at least 1 month prior to LOXO-292 administration. * Participant is not currently or has not previously being on hemodialysis * Baseline estimated glomerular filtration rate (eGFR) based on the Modification of Diet in Renal Disease (MDRD) equation at screening as follows: * Severe Renal Impairment (RI): \< 30 milliliter per minute (mL/min)/1.73m² * Moderate RI: ≥ 30 and \< 60 mL/min/1.73m² * Mild RI: ≥ 60 and \< 90 mL/min/1.73m² The MDRD equation is as follows (for females multiply result by 0.742, if African American multiply result by 1.212): eGFR = 175 x \[serum creatinine in milligrams per deciliter (mg/dL) measured with a standardized assay\]\^-1.154 x (Age)\^-0.203 Exclusion Criteria: For renal participants: * Has rapidly fluctuating renal function, as determined by historical measurements; or has demonstrated or suspected renal artery stenosis. Rapidly fluctuating renal function is defined as creatinine clearance or eGFR that differs by more than 20% within at least 3 months of the screening creatinine clearance or eGFR. If historical measurements are not available, then the 2 screening measurements will be used to demonstrate stability. * Participants who have had a renal transplant, a nephrectomy, or participants with a known history of nephrotic syndrome. * Participants who have required new medication for renal disease within 30 days prior to Check-in