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Epilepsy study reveals hidden forgetfulness in navigation skills

NCT ID NCT06847152

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how people with temporal lobe epilepsy (TLE) remember spatial information, like directions, compared to healthy volunteers. Researchers tested memory right after a navigation task and again six weeks later. They wanted to see if people with TLE forget spatial details faster than others, and if the side of the brain affected by epilepsy (right or left) makes a difference. The goal was to better understand memory problems in epilepsy, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Feb 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- healthy volunteers meeting each of the following criteria: * Aged over 18 years * Right-handed\* * Free of known neurological pathology * Signed consent * Matched in age (+ or - 5 years) and gender with epileptic patients presenting the characteristics below: * Right-handed\* * adult * presenting temporal lobe epilepsy, whose lateralization of the epileptogenic focus (right or left) has been objectified by an examination (EEG and/or MRI), * having carried out a neuropsychological assessment including the navigation task, * having been informed of the study, and consenting to the processing of their data Exclusion Criteria: * Person referred to in Article L1121-5 of the Public Health Code: Pregnant, parturient, or breastfeeding women * Person referred to in Article L1121-6 of the Public Health Code: persons deprived of their judicial or administrative freedom * Person referred to in Article L1121-8 of the Public Health Code: persons subject to a legal protection measure or unable to express their consent * Person referred to in Article L1121-8-1 of the Public Health Code: persons not affiliated to a social security scheme * Left-handed participants * Participants familiar with the premises of the Centre Hospitalier Métropole Savoie * Not speaking French Exclusion criteria Patients who have undergone epilepsy neurosurgery between the initial visit and the secondary visit of the neuropsychological assessment will not be paired with a healthy volunteer. Their data will not be studied. Volunteers whose pretest scores reveal a cognitive disorder (pathological threshold \> 1.65) will not perform the navigation task. They will then be referred to a neurologist.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Métropole Savoie

    Chambéry, Savoie, 73011, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.