Epilepsy study reveals hidden forgetfulness in navigation skills
NCT ID NCT06847152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how people with temporal lobe epilepsy (TLE) remember spatial information, like directions, compared to healthy volunteers. Researchers tested memory right after a navigation task and again six weeks later. They wanted to see if people with TLE forget spatial details faster than others, and if the side of the brain affected by epilepsy (right or left) makes a difference. The goal was to better understand memory problems in epilepsy, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \- healthy volunteers meeting each of the following criteria: * Aged over 18 years * Right-handed\* * Free of known neurological pathology * Signed consent * Matched in age (+ or - 5 years) and gender with epileptic patients presenting the characteristics below: * Right-handed\* * adult * presenting temporal lobe epilepsy, whose lateralization of the epileptogenic focus (right or left) has been objectified by an examination (EEG and/or MRI), * having carried out a neuropsychological assessment including the navigation task, * having been informed of the study, and consenting to the processing of their data Exclusion Criteria: * Person referred to in Article L1121-5 of the Public Health Code: Pregnant, parturient, or breastfeeding women * Person referred to in Article L1121-6 of the Public Health Code: persons deprived of their judicial or administrative freedom * Person referred to in Article L1121-8 of the Public Health Code: persons subject to a legal protection measure or unable to express their consent * Person referred to in Article L1121-8-1 of the Public Health Code: persons not affiliated to a social security scheme * Left-handed participants * Participants familiar with the premises of the Centre Hospitalier Métropole Savoie * Not speaking French Exclusion criteria Patients who have undergone epilepsy neurosurgery between the initial visit and the secondary visit of the neuropsychological assessment will not be paired with a healthy volunteer. Their data will not be studied. Volunteers whose pretest scores reveal a cognitive disorder (pathological threshold \> 1.65) will not perform the navigation task. They will then be referred to a neurologist.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Hospitalier Métropole Savoie
Chambéry, Savoie, 73011, France
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Other studies related to the condition(s) this trial covers.
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