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Study reveals how women's appetite shifts with their monthly cycle

NCT ID NCT06327087

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how appetite, food intake, and energy levels change during different phases of the menstrual cycle in healthy women aged 18-35. Researchers measured eating behavior in both lab and real-life settings, along with hormones, metabolism, and body composition. The goal was to better understand why some women eat more at certain times of the month.

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Study facts

What this study's own registry entry says, in plain language.

Participants

31 people

The number who actually took part.

Started

Jun 2022

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy sedentary or recreationally active females with normal menstrual cycles

Ages

18 to 35 years

Sex

Female participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex * Age: 18 - 35 years * Nulliparous * Body mass index (BMI): 18.5 - 24.9 kg/m2 * Premenopausal, with regular menstrual cycle (every 21-38 days, by self-report) * Sedentary or recreationally active, defined as: \<300 minutes per week of voluntary exercise at moderate intensity or greater over the past 12 weeks * Not currently pregnant or lactating, not planning to become pregnant in the next 12 weeks * Ability and willingness to fast for 12 hours before each study day visit * If applicable: * For people who occasionally (i.e., \<1x/day) use cannabis (including cannabidiol-based products): ability and willingness to abstain from cannabis for two days prior to each study day visit, the day of each study visit, and during each ad libitum diet phase. * For people who use cannabis daily: ability and willingness to continue to use the exact same amount of cannabis as they normally use for two days prior to each study day visit, the day of each study visit, and during each ad libitum diet phase. Exclusion Criteria: * Current or previous major comorbidities, by self-report, including: * Cardiovascular diseases * Diabetes (type 1 or type 2) * Cancer * Thyroid diseases * Human immunodeficiency virus or hepatitis B or C * Renal diseases * Hepatic diseases * Polycystic ovary syndrome * Uncontrolled/untreated (self-report): * Hypertension (or measured diastolic blood pressure \> 100 mm HG or systolic blood pressure \> 160 mm HG) * Dyslipidemia * Sleep disorders * Any other condition that may affect appetite and energy balance * Currently or in the past six months: * Use of oral contraceptive pills, or any other hormone-related birth control * Progestin-releasing intrauterine device * Use of any hormone therapy/medication ( except medication for thyroid conditions, that has not been altered for \>6 months) * Use of regular medication that may affect appetite, energy balance, or sleep * Regular use of tobacco or nicotine products * Starting any new prescription medication within two weeks of the first study day visit or during the study * If applicable, inability to abstain from supplements or herbal products that may impact sex hormones (e.g., chastetree, phytoestrogens, calcium d glucarate, soy isoflavones, maca, black cohosh, red raspberry, etc.) for two weeks prior to the first study day visit and until the second study day visit and free-living assessments are completed. * Working night shifts or traveling across more than 2 time zones within two weeks of and throughout the study * Food intolerances or allergies that cannot be accommodated * History of surgical procedure for weight loss at any time (e.g. gastroplasty, gastric bypass, gastrectomy or partial gastrectomy, adjustable banding, gastric sleeve); history of extensive bowel resection for other reasons * Current alcohol or substance abuse (score \>1 on the cut down-annoyed-guilty-eye opener \[CAGE\] questionnaire) * Current or past history of eating disorders including anorexia nervosa, bulimia, binge eating disorder (self-report or score \>20 on the Eating Attitudes Test - 26 \[EATS-26\] questionnaire) * Current severe depression or history of severe depression within the previous year, based on score \> 30 on Beck Depression Inventory (BDI) * Weight loss \>5kg in past 12 weeks for any reason * Weight loss of \>20 kgs in past 3 years for any reason

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Conditions

The condition(s) this trial relates to.

Appetitive Behavior Feeding Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of British Columbia - Okanagan

    Kelowna, British Columbia, V1V1V7, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.