Study reveals how women's appetite shifts with their monthly cycle
NCT ID NCT06327087
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how appetite, food intake, and energy levels change during different phases of the menstrual cycle in healthy women aged 18-35. Researchers measured eating behavior in both lab and real-life settings, along with hormones, metabolism, and body composition. The goal was to better understand why some women eat more at certain times of the month.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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31 people
The number who actually took part.
- Started
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Jun 2022
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy sedentary or recreationally active females with normal menstrual cycles
- Ages
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18 to 35 years
- Sex
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Female participants only
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female sex * Age: 18 - 35 years * Nulliparous * Body mass index (BMI): 18.5 - 24.9 kg/m2 * Premenopausal, with regular menstrual cycle (every 21-38 days, by self-report) * Sedentary or recreationally active, defined as: \<300 minutes per week of voluntary exercise at moderate intensity or greater over the past 12 weeks * Not currently pregnant or lactating, not planning to become pregnant in the next 12 weeks * Ability and willingness to fast for 12 hours before each study day visit * If applicable: * For people who occasionally (i.e., \<1x/day) use cannabis (including cannabidiol-based products): ability and willingness to abstain from cannabis for two days prior to each study day visit, the day of each study visit, and during each ad libitum diet phase. * For people who use cannabis daily: ability and willingness to continue to use the exact same amount of cannabis as they normally use for two days prior to each study day visit, the day of each study visit, and during each ad libitum diet phase. Exclusion Criteria: * Current or previous major comorbidities, by self-report, including: * Cardiovascular diseases * Diabetes (type 1 or type 2) * Cancer * Thyroid diseases * Human immunodeficiency virus or hepatitis B or C * Renal diseases * Hepatic diseases * Polycystic ovary syndrome * Uncontrolled/untreated (self-report): * Hypertension (or measured diastolic blood pressure \> 100 mm HG or systolic blood pressure \> 160 mm HG) * Dyslipidemia * Sleep disorders * Any other condition that may affect appetite and energy balance * Currently or in the past six months: * Use of oral contraceptive pills, or any other hormone-related birth control * Progestin-releasing intrauterine device * Use of any hormone therapy/medication ( except medication for thyroid conditions, that has not been altered for \>6 months) * Use of regular medication that may affect appetite, energy balance, or sleep * Regular use of tobacco or nicotine products * Starting any new prescription medication within two weeks of the first study day visit or during the study * If applicable, inability to abstain from supplements or herbal products that may impact sex hormones (e.g., chastetree, phytoestrogens, calcium d glucarate, soy isoflavones, maca, black cohosh, red raspberry, etc.) for two weeks prior to the first study day visit and until the second study day visit and free-living assessments are completed. * Working night shifts or traveling across more than 2 time zones within two weeks of and throughout the study * Food intolerances or allergies that cannot be accommodated * History of surgical procedure for weight loss at any time (e.g. gastroplasty, gastric bypass, gastrectomy or partial gastrectomy, adjustable banding, gastric sleeve); history of extensive bowel resection for other reasons * Current alcohol or substance abuse (score \>1 on the cut down-annoyed-guilty-eye opener \[CAGE\] questionnaire) * Current or past history of eating disorders including anorexia nervosa, bulimia, binge eating disorder (self-report or score \>20 on the Eating Attitudes Test - 26 \[EATS-26\] questionnaire) * Current severe depression or history of severe depression within the previous year, based on score \> 30 on Beck Depression Inventory (BDI) * Weight loss \>5kg in past 12 weeks for any reason * Weight loss of \>20 kgs in past 3 years for any reason
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of British Columbia - Okanagan
Kelowna, British Columbia, V1V1V7, Canada
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