Your gut bacteria react differently to pork and chicken
NCT ID NCT03539666
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers at South Dakota State University are running a controlled feeding study to see how two different diets, one based on pork and one on chicken, change the mix of bacteria in the gut and the compounds they produce. Thirty-eight healthy adults aged 50 and older who normally eat meat will eat meals prepared by the study team. The goal is to understand whether these diet-driven changes in gut bacteria relate to risk factors for heart and metabolic disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- controlled diets based on pork or chicken
- What this could lead to
- If researchers find that one meat affects gut bacteria and heart-related compounds differently, it could help shape dietary advice for older adults who eat meat regularly.
- What could go wrong
- This small study of 38 people tests short-term diet changes, so any differences may not last or apply to other groups. It cannot prove that either meat causes heart problems.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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38 people
The number who actually took part.
- Started
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Jul 2018
- Finished
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Apr 2019
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * generally good health status based on one routine physical in the past 15 months, current health status * normal HbA1C, weigh 110 lb or more * Age 50 years or more, generally healthy, all races and both sexes * generally practicing a meat-based dietary pattern, do not have any special dietary requirement, and * willingness to comply with the study protocol, including on-site meal consumption and sample/data collection. Exclusion Criteria: * medication usage, probiotic, long-term antibiotic, and tobacco/drug/alcohol use * Not on any special diet within 3 months of recruitment, and do not have any intention to lose weight. * impaired kidney functions * Active history of cancer, diabetes, heart, liver, and kidney diseases * major gastrointestinal disorders in the past 3 months * history of heart attacks or stroke * Unable to meet in-person visit requirements for dining, picking up meals, and tests * Any mental health condition that would affect the ability to provide written informed consent. * If they had not had a routine health checkup during the 12 months prior to recruitment. * If they were unwilling to abstain from taking nutritional supplements, alcohol, non-study foods, and beverage during the study period.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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South Dakota State University, Wagner Hall 416
Brookings, South Dakota, 57007, United States
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