Drug interaction study checks if new compound BI 764198 alters metformin in the body
NCT ID NCT07368569
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This completed Phase 1 trial in 14 healthy adults tested whether taking BI 764198 along with metformin changes how much metformin gets into the blood. Participants received both drugs together or metformin alone in a crossover design. The goal was to see if there is a drug interaction, which helps guide safe use in future studies.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Humanpharmakologisches Zentrum Biberach
Biberach, 88397, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BI 764198 and metformin hydrochloride
What this could lead to
If successful, this study could help doctors understand whether BI 764198 can be safely combined with metformin in future treatments.
What could go wrong
This is a very early, small study in healthy people, not patients. It only looks at drug levels, not whether the combination works for any disease.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.