Scientists test if common drugs can stop an LSD trip
NCT ID NCT05964647
First seen Nov 17, 2025 · Last updated Jun 19, 2026 · Updated 27 times
Summary
This study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD can make the psychedelic effects shorter or weaker. Twenty healthy adults took LSD and then one of these drugs or a placebo. The goal was to see how the drugs changed the intensity and duration of the LSD experience.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University Hospital Basel
Basel, Canton of Basel-City, 4055, Switzerland
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LSD, ketanserin, olanzapine, lorazepam
What this could lead to
If successful, this could help develop ways to manage or shorten intense psychedelic experiences in therapeutic or emergency settings.
What could go wrong
This is a very small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world use, and the drugs tested have their own side effects.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.