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Sleepless nights may amplify pain, study suggests

NCT ID NCT06336109

Knowledge-focused Sponsor: Aalborg University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how disrupted sleep changes the way healthy adults feel pain and move their joints. Thirty participants received painful injections in the knee and shoulder after a night of fragmented sleep. Researchers measured pain intensity and movement patterns to understand the link between sleep loss and pain sensitivity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Hypertonic saline injection
What this could lead to
If successful, this could help explain why poor sleep makes pain worse, pointing toward better pain management strategies.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. Results may not apply to real-world chronic pain conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy men and women aged 18-45 years * Must have a smartphone available during the experiment Exclusion Criteria: * Pregnancy * Drug addiction, defined as the use of cannabis, opioids, or other drugs * Previous or current neurologic or musculoskeletal illnesses * Current pain * Lack of ability to cooperate

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Conditions

The condition(s) this trial relates to.

Pain Parasomnias sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy Pain Sleep disturbance

Contacts and locations

Locations

  • Aalborg University

    Aalborg, North Denmark, 9000, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.