Healthy hearts reveal aging secrets in new MRI study
NCT ID NCT03064503
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 74 healthy adults aged 20 to 80 to understand how natural aging affects heart muscle scarring (fibrosis) and heart function. Participants had MRI scans, blood tests, and skin measurements to detect fibrosis. The goal was to learn how aging alone changes the heart, without the influence of disease or lifestyle factors.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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74 people
The number who actually took part.
- Started
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Feb 2017
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * physical activity ≤ 3 x(30') per week * no history of smoking, diabetes, myocardial infarction, heart failure, hypertension (\<140 or \<90 mmHg) and no anti-hypertensive or cardiovascular-related medications * no familial history of early myocardial ischemia * body mass index (BMI) \<30kg/m2 * normal routine lipid blood analysis * glycemia \<1.26g/l * normal electrocardiogram (ECG) Exclusion Criteria: * arrhythmia * hepatic insufficiency * pregnancy * claustrophobia * MRI contrast allergy, * general contraindications to MRI such as pacemaker, etc.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Département de Radiologie, CHU Saint-Etienne - Hôpital Nord
Saint-Etienne, 42270, France
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