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Scientists zap brains to unlock memory secrets

NCT ID NCT05374551

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different parts of the brain work together to help us remember events. Researchers used a gentle magnetic pulse (TMS) to briefly change brain activity in 41 healthy young adults while they performed memory tasks. The goal was to understand which brain regions are essential for forming and recalling memories, not to treat any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

41 people

The number who actually took part.

Started

Oct 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ages 18 to 35 years old * Fluent in English * Free of major neurological or psychiatric illness * Right-handed * Normal or corrected to normal vision Exclusion Criteria: * History of a psychiatric illness within the past two years * History of a learning disorder (e.g., attention deficit disorder, dyslexia) * History of neurological disorder or brain injury, including family history of epilepsy, convulsions or seizures, stroke; vascular, traumatic, tumoral, infectious, or metabolic lesion of the brain, even without a history of seizure, and without anticonvulsant medication, and any unexplained lifetime loss of consciousness/syncope * Use of medications that reduce seizure threshold (e.g., tricyclic antidepressants, neuroleptic agents) * History of neurosurgery * History of heart disease * Recreational drug use in the past two months * Uncontrollable shaking, or inability to sit/lie still for one hour * Evidence of neurological disorders or structural abnormalities, based on MRI * Pregnancy * Prior surgeries, conditions, and/or implants that are not MRI-safe, including: pacemaker, pacemaker wires, artificial heart valve, brain aneurysm surgery, middle ear implant, non-removable hearing aids, braces, or extensive dental work, implanted mechanical or electrical device, artificial limb or joint * Foreign metallic objects in the body, such as bullets, BBs, shrapnel, or metalwork fragments * History of metal work or ocular metallic foreign bodies * History of uncontrolled migraines or susceptibility to headaches * Use of centrally-acting medications and drugs, with the exception of caffeine, within the last 12 hours * Concurrent treatment with ototoxic medications * Current sleep deprivation, extreme fatigue, or recent jet lag * Claustrophobia * Pre-existing noise induced hearing loss * Any prior adverse experience (e.g. physical or psychological discomfort) with repetitive TMS or MRI scanning

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston College

    Chestnut Hill, Massachusetts, 02467, United States

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