Scientists zap brains to unlock memory secrets
NCT ID NCT05374551
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how different parts of the brain work together to help us remember events. Researchers used a gentle magnetic pulse (TMS) to briefly change brain activity in 41 healthy young adults while they performed memory tasks. The goal was to understand which brain regions are essential for forming and recalling memories, not to treat any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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41 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18 to 35 years old * Fluent in English * Free of major neurological or psychiatric illness * Right-handed * Normal or corrected to normal vision Exclusion Criteria: * History of a psychiatric illness within the past two years * History of a learning disorder (e.g., attention deficit disorder, dyslexia) * History of neurological disorder or brain injury, including family history of epilepsy, convulsions or seizures, stroke; vascular, traumatic, tumoral, infectious, or metabolic lesion of the brain, even without a history of seizure, and without anticonvulsant medication, and any unexplained lifetime loss of consciousness/syncope * Use of medications that reduce seizure threshold (e.g., tricyclic antidepressants, neuroleptic agents) * History of neurosurgery * History of heart disease * Recreational drug use in the past two months * Uncontrollable shaking, or inability to sit/lie still for one hour * Evidence of neurological disorders or structural abnormalities, based on MRI * Pregnancy * Prior surgeries, conditions, and/or implants that are not MRI-safe, including: pacemaker, pacemaker wires, artificial heart valve, brain aneurysm surgery, middle ear implant, non-removable hearing aids, braces, or extensive dental work, implanted mechanical or electrical device, artificial limb or joint * Foreign metallic objects in the body, such as bullets, BBs, shrapnel, or metalwork fragments * History of metal work or ocular metallic foreign bodies * History of uncontrolled migraines or susceptibility to headaches * Use of centrally-acting medications and drugs, with the exception of caffeine, within the last 12 hours * Concurrent treatment with ototoxic medications * Current sleep deprivation, extreme fatigue, or recent jet lag * Claustrophobia * Pre-existing noise induced hearing loss * Any prior adverse experience (e.g. physical or psychological discomfort) with repetitive TMS or MRI scanning
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Boston College
Chestnut Hill, Massachusetts, 02467, United States
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