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Broccoli's hidden messages: can plant molecules talk to our cells?

NCT ID NCT07456267

Knowledge-focused Sponsor: IMDEA Food Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether small molecules called microRNAs from broccoli can be absorbed into the blood and affect gut bacteria in 20 healthy adults. Participants ate broccoli, and researchers measured these plant molecules in blood and stool samples. The goal was to understand a possible 'cross-kingdom' communication, not to treat any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Feb 2025

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women \> 18 years and \< 45 years * Adequate cultural level and understanding of the clinical study. * Agree to voluntarily participate in the study and give their written informed consent. Exclusion Criteria: * Intolerance to broccoli * Having to follow some type of dietary restriction that prevents the consumption of broccoli. * Not willing to consume the food in the required quantity and/or frequency. * Subjects with severe disease (hepatic, renal, cardiovascular, etc.) * Subjects under any type of pharmacological treatment. * Having taken antibiotics 1 month before the start of the study (Specific for the 2-week long study). * Pregnancy or breastfeeding. * Subjects who refuse to collect stool samples or undergo the blood draws scheduled in the study. * Not able or willing to travel to the study site.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • Imdea-Food

    Madrid, Madrid, 28049, Spain

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