Your DNA may decide how sore that workout leaves you
NCT ID NCT06740136
First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time
Summary
Researchers want to know whether a person's genes affect how much muscle damage they get from intense exercise. The study enrolls 300 healthy athletes aged 18 to 35 who belong to sports clubs. Participants do a bout of eccentric exercise that stresses muscles, and researchers track levels of creatine kinase, a blood marker of muscle damage, before and after. They then look for links between those changes and genetic variations.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- muscle-damaging eccentric exercise
- What this could lead to
- If researchers find gene variants linked to muscle damage, this could one day help athletes and coaches tailor training to each person's biology.
- What could go wrong
- This is an exploratory study with no pre-selected genes, so it may find no clear genetic link. Results from young, trained athletes may not apply to other people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
300 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female * Aged between 18 and 35 * Weighing more than 50 kg * Member of a sports club affiliated to an Olympic federation * Socially insured * Willing to comply with all study procedures and duration of the study Exclusion Criteria: * Medical history contraindicating sporting activities * Current medical treatment * Not a member of a sports club affiliated to an Olympic federation * Administrative reasons: impossibility of receiving informed information, impossibility of participating in the entire study, absence of social security coverage, refusal to sign consent form.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eurasport
Loos, 59120, France
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