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Can pictures of smells cure motion sickness in virtual reality?

NCT ID NCT05308433

Knowledge-focused Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how different visual prompts—like words, pictures, or colors—activate the brain's smell center in 30 healthy adults. Using fMRI scans, researchers aimed to find the best way to trigger a sense of smell through imagination. The goal is to use this knowledge to reduce cybersickness (motion sickness from virtual reality). This is an observational study, not a treatment trial.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Apr 2022

Finished

Oct 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * to be of French nationality who has always lived in metropolitan France; * to be right-handed person; * to be enrolled in a social security plan; * to be able to understand the instructions given; * to have underwent a pre-inclusion medical examination; * to give a written consent; * Person with a strong capacity for olfactory imagination: having obtained a score strictly below 2.5 on the fVOIQ olfactory imagination questionnaire. Exclusion Criteria: * to have an inability to read French; * to be recognized as a synesthete; * to have a professional activity requires intense olfactory activity; * to have a partial or total loss of smell (hyposmia, anosmia); * to have qualitative smell disorders (carcosomia, hyperosmia, phantosmia, parosmia); * to have smell disorders of neurological, post-traumatic or neurodegenerative origin; * to have uncorrected or poorly corrected visual disturbances; * to have vestibular disorder diagnosed; * any contraindication to MR examination (active medical device, ferromagnetic foreign body, pregnancy, morbid obesity, claustrophobia, … ); * subject under a measure of legal protection.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • CHRU Nancy

    Nancy, France

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