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Ketamine's brain impact revealed in small stanford study

NCT ID NCT03475277

First seen Jan 11, 2026 · Last updated Jun 22, 2026 · Updated 23 times

Summary

This completed Stanford study looked at how ketamine changes activity in brain areas linked to reward and risk. Thirteen healthy adults who had used ketamine before underwent brain scans while performing tasks. The goal was to understand ketamine's effects on brain circuits, not to treat any disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Stanford Psychiatry

    Palo Alto, California, 94304, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketamine

What this could lead to

If successful, this could help explain how ketamine alters brain reward pathways, potentially guiding future treatments for addiction or mood disorders.

What could go wrong

This is a very small, early biomarker study with only 13 healthy participants, so results may not apply to broader populations or lead directly to treatments.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.