New inhaled drug passes first safety check in small human study

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Healthy male or female subjects. 2. Aged 18 to 45 years (inclusive) at screening. 3. Body weight: Male ≥ 50.0 kg, Female ≥ 45.0 kg; Body Mass Index (BMI): 19.0 - 28.0 kg/m² (inclusive). 4. Capable of understanding and providing written informed consent. 5. Able and willing to adhere to the study protocol. Exclusion Criteria: 1. Clinically significant abnormalities in screening assessments (physical exam, vital signs, labs, chest X-ray, ophthalmology). 2. Pulmonary function: FEV1/FVC \< 80% at screening. 3. Positive serology for HBsAg, HCV, HIV, or TP-Ab. 4. Clinically significant 12-lead ECG abnormalities or QTcF \> 450 ms (male) / \> 470 ms (female). 5. Acute or chronic oral/pharyngeal disease. 6. History or presence of significant chronic diseases of any major organ system. 7. History of specific diseases (glaucoma, constipation, BPH, urinary obstruction, epilepsy, hyperthyroidism, etc.). 8. History of short or long QT syndrome. 9. Respiratory infection within 6 weeks (lower) or 2 weeks (upper) prior to screening. 10. Major surgery within 3 months prior to screening or planned during study. 11. Hypersensitivity to study drug components or related drugs. 12. History or evidence of drug abuse or positive drug screen. 13. Excessive daily intake of tea, coffee, or caffeine (\>8 cups) within 3 months prior to screening. 14. Inability to refrain from certain foods/beverages containing caffeine/xanthine/glucose. 15. Excessive alcohol consumption or positive alcohol screen. 16. Smoking ≥5 cigarettes per day within 3 months prior to screening or positive nicotine test. 17. Use of any drugs (including herbs/vitamins) within 30 days prior to screening. 18. Participation in another clinical trial within 3 months prior to screening. 19. Blood donation/loss (\>400 mL) within 3 months prior to screening or planned during/after study. 20. Difficulty with venipuncture or intolerance to intravenous access. 21. History of needle or blood phobia. 22. Intolerance to inhaled administration. 23. Pregnancy, lactation, or positive pregnancy test. 24. Unwillingness to use effective contraception during and for 6 months after the study. 25. Special dietary requirements or inability to comply with standardized diet. 26. Poor compliance as judged by the investigator. 27. Any other condition considered unsuitable for participation by the investigator.