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Bee glue may help your gums heal faster after a tooth pull

NCT ID NCT07665814

Symptom relief Sponsor: Saint-Joseph University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This small pilot study tested whether a natural propolis-based solution (mixed with clove and willow bark) could help gums heal faster after a tooth extraction. Fourteen healthy adults each had two similar teeth pulled on opposite sides of the mouth. One socket got the propolis solution three times a day for a week, while the other got only a saltwater rinse. Healing was tracked with 3D scans and pain scores. The goal was to see if this natural remedy could be a cheap, safe way to support recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Propolis-based topical solution (52% propolis extract, clove oil, white willow bark extract)
What this could lead to
If it works, this could offer a natural, low-cost option to speed up gum healing after tooth removal.
What could go wrong
This is a very small pilot study (14 people) with no blinding, so results may not be reliable or apply to everyone. The treatment is only tested for 7 days.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

14 people

The number who actually took part.

Started

Oct 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cooperative adult patients willing to accept the study protocol * Minors with a cooperative parent/legal guardian providing consent * Non-surgical extraction of bilaterally positioned teeth * Low-to-moderate extraction difficulty per the Pederson scale * Systemically healthy, with no history of systemic disease Exclusion Criteria: * Non-consenting patients * Failure to attend follow-up appointments per protocol * Heavy smokers (\>10 pack-years) * Systemic disease (e.g., diabetes mellitus, immunosuppressive syndromes) * Current use of contraceptive medication * Systemic antibiotic therapy within the previous 3 months * Anticoagulant therapy within the previous 4 weeks * Requirement for antibiotic prophylaxis * Pregnant or breastfeeding women * Known allergy to honey or bee-related products * Known allergy to local anesthetics used in dental procedures * Higher-difficulty extractions requiring sutures or other hemostatic measures

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy

Contacts and locations

Locations

  • Saint Joseph University of Beirut

    Beirut, Lebanon

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