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Scientists probe the Body's inner workings during peak performance

NCT ID NCT05359744

Knowledge-focused Sponsor: Paracelsus Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed pilot study examined how the body's molecules change during intense exercise. Researchers analyzed blood and saliva from 80 healthy male elite cyclists and recreational athletes before, during, and after a bike test. The goal was to better understand the complex biological processes triggered by physical activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could improve our understanding of how exercise affects the body at a molecular level, potentially guiding future training or recovery strategies.
What could go wrong
This is a small pilot study with only 80 participants, so results may not apply to everyone. It is observational and does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Oct 2021

Finished

Aug 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All arms: ability to give written informed consent * Arms 1- 3: inconspicuous medical examination (medical history, resting ECG, echocardiography) * Elite athletes (arm1, cyclists): maximum oxygen uptake \> 65 ml/kg/KG * Elite athletes (arm1, cyclists): participation in cycling competitions on a regular basis * Recreational athletes (arms 2 and 3): maximum oxygen uptake \< 65 ml/kg/KG for male subjects and \< 55 ml/kg/KG for female subjects Exclusion Criteria: * All arms: unable to communicate adequately by language * All arms: regular use of prescription drugs other than thyroxine or antihistamines * All arms: alcohol consumption as equivalent doses averaging more than 40 g of pure alcohol per day * All arms: use of illicit drugs * All arms: known diseases of the cardiovascular system * All arms: arterial hypertension over 160/90 mmHg at rest * All arms: known pulmonary diseases, especially bronchial asthma * All arms: surgery less than 4-6 months ago. * All arms: abnormalities in the medical examination (medical history, resting ECG, echocardiography) * Arms 1-3: orthopaedic diseases that preclude maximum exercise on a bicycle ergometer * Elite athletes (arm1, cyclists): maximum oxygen uptake \< 65 ml/kg/KG * Recreational athletes (arms 2 and 3): maximum oxygen uptake \> 65 ml/kg/KG for male subjects and \> 55 ml/kg/KG for female subjects * Arm 3: positive urine ß-HCG

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise Exercise test Healthy Physical fitness

Contacts and locations

Locations

  • Paracelsus Medical University

    Salzburg, 5020, Austria

More trials for these conditions

Other studies related to the condition(s) this trial covers.