EXERCISE

This study tests two different home exercise programs to see which one better helps people with Parkinson's disease avoid falls. Thirty participants will do exercises at home for six weeks, and researchers will check their balance, walking, and fear of falling. The goal is to fin…

This study looks at two add-on treatments for Duchenne muscular dystrophy (DMD): a drug called tadalafil that improves blood flow, and aerobic exercise training. The goal is to see if these can improve muscle function and delay disease progression. About 50 ambulatory children wi…

This study tests whether using a Fitbit with or without health coaching helps adults aged 40+ with central obesity (large waistline) become more active and improve heart health. Over 1 year, 133 participants will either continue their usual routine, use a Fitbit alone, or use a F…

This study looks at whether doing aerobic exercise before eating (fasted) is better for heart health and weight loss than exercising after a meal. Over 16 weeks, 40 adults with overweight or obesity will be assigned to either fasted or fed exercise. Researchers will measure chang…

This study looks at whether a combination of physical exercise and a thermogenic nutritional supplement can help improve body composition, metabolism, and overall health in adults aged 50-65 who are overweight but not obese. Participants must have at least two signs of metabolic …

This study tests whether a dietary supplement called capsinoid, found in sweet peppers and chilies, can activate brown fat in obese teenagers. Brown fat is a type of body fat that burns energy to produce heat, which may help with weight control. The study will involve 38 adolesce…

This study tests whether a virtual assistant (a chatbot) can help older adults stay on track with a home exercise program. Seventy people aged 60 and older will either use the chatbot for 12 weeks or join a standard in-person class. The main goal is to see if the chatbot group co…

This study looks at whether a lentil protein extract is safe for healthy adults and if it can help control blood pressure, improve blood vessel function, and boost exercise performance. Researchers will give different doses to 48 healthy men and women aged 18 to 45 and monitor fo…

This study tests whether combining a stepped-care counseling program with an exercise program can improve mental and physical well-being in Latina cancer survivors. Twenty participants who are currently in or recently finished cancer treatment will take part. Researchers will mea…

This study looks at whether qigong (a gentle movement practice) or multicomponent exercise can help people with panic disorder feel less anxious and improve their physical health. Researchers will enroll 60 adults aged 18-65 who have been diagnosed with panic disorder. Participan…

This study tests whether adding motivational counseling to a virtual exercise program helps cancer survivors stay active. About 236 people who finished cancer treatment within the last 5 years will join a 6-month program with supervised exercise and either standard or enhanced co…

This study tests whether a natural supplement can increase collagen production in the body when taken with collagen protein. Researchers will measure collagen markers in the blood of 20 healthy young adults after exercise. They will also use participants' blood to see if it stren…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 6 weeks can improve lung function, muscle strength, and quality of life in people with hemiplegia (weakness on one side) after a stroke. About 54 adults who are at least 3 months post-stroke will be rand…

This study tests whether adding whole-body vibration exercises to mineral bath therapy (balneotherapy) can better reduce pain, improve physical function, and enhance sleep quality in people with chronic low back pain. Sixty adults aged 18 to 65 with long-lasting back pain will be…

This study tests whether fun, child-friendly core exercises can improve balance and daily movement in children aged 6-12 with spastic cerebral palsy. 54 children will either do these special exercises or a standard home program for 8 weeks. The goal is to see if the fun exercises…

This study looks at whether a 10-week exercise program, done in-person or online, can help people with multiple myeloma maintain their physical fitness, muscle strength, and quality of life while they undergo chemotherapy before a stem cell transplant. The trial will include 30 a…

This study looks at whether the BETY exercise program, which combines physical exercises with emotional and social support, can improve pain and quality of life in people with knee osteoarthritis who have already received a joint injection. About 60 adults with moderate knee oste…

This study compares high-intensity laser therapy with exercise to see which better reduces pain and improves hand function in people with thumb osteoarthritis. About 42 adults with thumb joint arthritis and at least moderate pain will be randomly assigned to one of the two treatm…

This study tests whether adding very short, intense exercises called 'exercise-snacks' to a standard weight-management program can improve physical fitness in obese adolescents. Forty-eight hospitalized teens will either do six mini-workouts daily for three weeks or receive stand…

This study tests whether special breathing exercises (inspiratory muscle training) can help people with substance use disorder. Researchers will measure changes in lung function, shortness of breath, cough strength, exercise ability, cravings, depression, anxiety, and quality of …

This study compares two hands-on treatments—kinesiotaping (a special tape) and peloidotherapy (mud packs)—plus home exercises, against exercises alone for people with mild-to-moderate carpal tunnel syndrome. 90 adults will be randomly assigned to one of three groups. The goal is …

This study looks at whether the number of steps a person takes each day, measured by a smartwatch, can help predict how well breast cancer treatment works. About 82 women with a certain type of breast cancer will wear a smartwatch during their treatment. The goal is to see if mor…

This study looks at whether exercise before surgery can increase immune cells inside oesophageal cancer tumors. Researchers will ask 50 adults with advanced oesophageal cancer to follow a high- or low-intensity exercise program. They will then measure immune cells in blood and tu…

This study explores whether mild low-oxygen (hypoxic) conditioning, alone or combined with exercise, can improve blood vessel health in the brains of inactive older adults aged 60-80. Researchers will measure changes in brain blood flow and other health markers. The goal is to fi…

This study looks at how the right side of the heart works in people with COPD, both at rest and during exercise. Researchers want to find different patterns of heart strain to help develop better treatments in the future. The study involves 60 adults aged 40 and older with COPD.

This study tests whether using a virtual reality headset during exercise can reduce the effort it takes to breathe. Ten healthy adults will cycle with and without VR to see if it lowers breathing strain and anxiety. The goal is to gather early evidence for a possible non-drug way…

This study looks at how exercise during and after pregnancy changes breast milk and whether those changes affect a baby's growth and risk of obesity. Researchers will measure breast milk composition and infant body fat in 200 mothers and their babies. The goal is to learn how phy…

This study looks at whether planning workouts around menstrual cycle phases improves fitness in female athletes. About 111 healthy women who exercise regularly will be placed into different training groups for 12 weeks. Researchers will measure changes in aerobic fitness, muscle …

This study looks at whether aerobic exercise (stationary biking) and daytime naps can help people with relapsing-remitting multiple sclerosis learn and remember motor skills. Twenty adults aged 18-70 will take part. The goal is to see if these simple activities can boost brain fu…

This study looks at how doing mat Pilates for 8 weeks changes body awareness and physical activity levels in sedentary women ages 18 to 29. About 54 women will take part, with half doing Pilates and the other half as a control group. The goal is to measure changes using surveys, …

This study looks at how different amounts of indoor cycling training change gut bacteria and related health markers in healthy, active men aged 18 to 45. Participants will be placed into one of three groups: no structured training, moderate cycling, or high-load cycling. Research…

This study looks at whether adding breathing muscle training to standard rehab helps people with rheumatoid arthritis who also have lung disease. Researchers will check changes in exercise ability, breathlessness, and a specific gene (HOTAIR). About 39 adults will take part, and …

This study is for 700 people already living with a chronic disease like arthritis, depression, or heart disease. Researchers will use a small movement sensor worn for 5 days every 4 months to track physical activity and sitting time. The goal is to see if a person's unique activi…

This study looks at whether a mobile app called BumptUp can help pregnant women who don't currently exercise become more active and improve their heart health. Researchers will compare two groups of 50 healthy pregnant women in their second trimester: one group uses the app for 8…

This study looks at how blood sugar levels change during exercise in healthy adults and those with type 1 diabetes. Researchers want to see if these changes are similar each time a person exercises. Participants will cycle or rest after a standard breakfast, and their glucose wil…

This study explores how a natural heart hormone, called natriuretic peptide, influences metabolism and exercise in people with different genetic makeups. Researchers will measure hormone levels and energy use in 200 adults after a sugary drink and exercise. The goal is to underst…

This study looks at how a drink with caffeine and green tea extracts changes the way your body burns fat at rest, during exercise, and after a workout. Researchers will measure fat oxidation in 40 healthy adults aged 18 to 45 who are moderately active. The goal is to understand i…

This study looks at whether high lactate levels in people with metabolic syndrome cause problems with fat breakdown and blood sugar control. Researchers will raise lactate levels in healthy volunteers using an IV infusion, then measure how the body handles fat and sugar during re…

This pilot study aims to find out if cold temperatures change how the body burns fat during exercise, and whether that change is different between females and males. Researchers will measure fat burning in 20 healthy adults aged 18-40 during exercise in both normal and cold condi…

This study looks at how the right side of the heart works in people with COPD, both at rest and during exercise. Researchers want to find different patterns of heart strain to help design better treatments in the future. About 60 adults aged 40 and older with COPD will take part.

This study looks at how histamines, the same molecules that cause allergy symptoms, affect blood flow in the lungs after exercise. Researchers will measure blood pressure in the lungs of 20 healthy adults aged 19-39 after they exercise, comparing results when histamine action is …

This study looks at whether doing core muscle exercises right after abdominal surgery can prevent incisional hernias and long-term pain. About 588 adults having abdominal surgery will be randomly assigned to either standard care or a core exercise program. The goal is to see if e…