EXERCISE

This study tests whether a natural supplement called capsinoid, found in sweet peppers and chilies, can activate brown fat in obese adolescents. Brown fat helps burn calories to produce heat, which may aid weight control. Researchers will measure temperature and blood flow in the…

This study tests whether using a Fitbit alone or with health coaching helps adults aged 40+ with central obesity (large waistline) move more and improve heart health. Over one year, 133 participants will either continue their usual routine, use a Fitbit with step and sleep goals,…

This study looks at whether doing aerobic exercise before eating (fasted) is better for heart health and weight loss than exercising after a meal. Over 16 weeks, 40 adults with obesity will follow an exercise program either fasted or fed. Researchers will measure changes in body …

This study looks at whether a combination of physical exercise and a thermogenic nutritional supplement can improve body composition, metabolism, and overall health in adults aged 50-65 who are overweight but not obese. Participants must have at least two signs of mild metabolic …

This study tests whether a virtual assistant (a chatbot) can help adults aged 60 and older complete a 12-week home exercise program. Seventy participants will either use the chatbot for guided workouts or attend in-person group classes. The goal is to see if the chatbot improves …

This study looks at how exercise and physical activity during and after pregnancy change the makeup of breastmilk. Researchers want to see if these changes affect how babies use energy and grow, which could help prevent childhood obesity. About 200 mothers who plan to breastfeed …

This study tests whether a child-friendly core exercise program, called Fun-Core, can improve balance and daily movement in children aged 6 to 12 with hemiplegic cerebral palsy. Half of the 54 participants will do the Fun-Core exercises at home three times a week for 8 weeks, whi…

This study tests whether a natural supplement can increase collagen production in the body when taken with collagen protein. Researchers will measure collagen markers in the blood of 20 healthy adults aged 18-30 after exercise. They will also use participants' blood to treat lab-…

This study tests whether a special breathing exercise program can help people with substance use disorder. Researchers will measure changes in lung function, shortness of breath, cough strength, exercise ability, cravings, mood, and quality of life. About 34 adults receiving inpa…

This study tests whether high-intensity laser therapy or exercise is better at reducing pain and improving hand function in people with thumb osteoarthritis. About 42 adults with thumb joint arthritis and at least moderate pain will be randomly assigned to one of the two treatmen…

This study looks at whether the BETY exercise program, which combines physical exercises with emotional and social support, can reduce pain and improve quality of life in people with knee osteoarthritis. Participants must have received a knee injection in the past month. The goal…

This study is testing a lentil protein extract for safety in 48 healthy adults aged 18-45. Researchers will also explore whether different doses can improve blood pressure, blood vessel function, and exercise performance. Participants will take the supplement or a placebo and be …

This study looks at whether adding motivational counseling to a virtual exercise program helps cancer survivors become more active. About 236 adults who finished cancer treatment within the last 5 years will take part. They will do supervised physical activity from home and recei…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 15 minutes a day, 5 days a week over 6 weeks can improve lung function, muscle strength, and quality of life in people who have had a stroke and have weakness on one side of the body (hemiplegia). About …

This study looks at whether a mobile app called BumptUp can help pregnant women who don't currently exercise get more motivated and improve their heart health. Researchers will compare two groups of healthy pregnant women in their second trimester: one group uses the app for 8 we…

This study tests whether adding very short, intense exercises called 'exercise-snacks' to a standard weight-management program can improve physical fitness in obese adolescents. Forty-eight teens will either do six mini-workouts daily for three weeks plus usual care, or just usua…

This study looks at whether qigong (a gentle mind-body exercise) or multicomponent exercise (a mix of activities) can reduce panic and anxiety symptoms in people with panic disorder. Researchers will measure changes in panic severity, anxiety, balance, walking, sleep, fatigue, pa…

This study tests whether adding whole-body vibration exercises to mineral bath therapy (balneotherapy) can better reduce pain, improve movement, and boost sleep in people with chronic low back pain. Sixty adults aged 18 to 65 with long-lasting back pain will be split into two gro…

This study looks at whether people with multiple myeloma can and want to join a 10-week exercise program while getting chemotherapy before a stem cell transplant. The program includes both in-person and online sessions. Researchers want to see if it helps maintain physical fitnes…

This study compares two hands-on treatments—kinesiotaping (a special tape) and peloidotherapy (mud packs)—plus home exercises, against exercises alone for people with mild-to-moderate carpal tunnel syndrome. 90 adults will be randomly assigned to one of three groups. The goal is …

This study tests whether combining a stepped-care counseling program with an exercise program can help Latina cancer survivors reduce stress, anxiety, and depression while increasing physical activity. About 20 participants who are currently in or recently finished cancer treatme…

This study looks at whether high lactate levels in people with metabolic syndrome cause problems with fat breakdown and blood sugar control. Researchers will raise lactate levels in healthy volunteers using an IV infusion and then measure how their bodies handle fat and sugar dur…

This study looks at how the right side of the heart works during rest and exercise in people with COPD. Researchers want to find different patterns of heart strain to guide future treatments. About 60 adults aged 40 and older with COPD will take part. The goal is to better unders…

This pilot study aims to find out if cold temperatures affect fat burning during exercise differently in females and males. Researchers will measure fat oxidation in 20 healthy adults aged 18-40 during exercise in both cold and neutral conditions. The study is observational and d…

This study looks at how blood sugar levels change during exercise in healthy adults and those with type 1 diabetes. Researchers want to see if these changes are similar each time a person exercises. Participants will cycle or rest after a standard breakfast, and their glucose wil…

This study looks at how histamines, the same molecules that cause allergy symptoms, affect blood flow in the lungs after exercise. Researchers will measure blood pressure in the lungs of 20 healthy adults aged 19-39 after they exercise, comparing results when histamine action is …

This study is for 700 people with chronic conditions like arthritis, diabetes, or heart disease. Researchers will use a small movement sensor worn for 5 days every 4 months to track physical activity and sitting time. The goal is to see if a person's unique activity pattern can p…

This study looks at how the right side of the heart works in people with COPD, both at rest and during different levels of exercise. Researchers want to find patterns of heart dysfunction that could lead to better treatments. The study involves 60 adults aged 40 and older with CO…

This study looks at how different amounts of indoor cycling training change gut bacteria and related health markers in healthy, active men aged 18 to 45. Participants will be placed into one of three groups: no structured training, moderate cycling, or high-intensity cycling. Res…

This study looks at whether scheduling workouts based on menstrual cycle phases improves fitness in female athletes. About 111 healthy women who exercise regularly will follow different training plans over three cycles. Researchers will measure changes in aerobic fitness, muscle …

This study tests whether using a virtual reality headset during exercise can reduce the effort needed to breathe. Ten healthy adults will cycle with and without VR to compare breathing effort, anxiety, and comfort. The goal is to see if VR can be a simple, non-drug way to help pe…

This study looks at whether doing mat Pilates for 8 weeks can help sedentary women aged 18-29 feel more connected to their bodies and become more active. Half of the 54 participants will do Pilates, while the other half will not. Researchers will measure changes using surveys abo…

This study looks at whether doing core muscle exercises right after abdominal surgery can prevent incisional hernias and long-term pain. About 588 adults having abdominal surgery will be randomly assigned to either standard care or a core exercise program. The goal is to see if e…

This study looks at whether the number of steps breast cancer patients take each day, tracked by a smartwatch, is linked to how well their treatment works. About 82 women with non-metastatic HER2-negative breast cancer will wear a Huawei Fit 2 smartwatch during neoadjuvant therap…

This study looks at whether breathing low-oxygen air (hypoxic conditioning), either by itself or combined with exercise, can improve blood vessel health in the brains of older adults. Researchers will enroll 64 inactive people aged 60 to 80 to test this approach. The goal is to f…

This study looks at how a natural heart hormone called atrial natriuretic peptide (ANP) affects metabolism and heart health. Researchers will compare people with a common genetic variation that lowers ANP levels to those with normal levels. Participants will undergo exercise and …

This study looks at whether exercise before surgery can help the immune system fight oesophageal cancer. Researchers will ask 50 adults with this cancer to follow a high or low intensity exercise program. They will then check blood and tumor samples for immune cells called CD8+ T…

This study looks at whether aerobic exercise (stationary biking) and daytime naps can improve how people with relapsing-remitting multiple sclerosis learn and remember motor skills. Twenty adults aged 18-70 will participate. The goal is to understand how these simple activities a…

This study looks at whether adding breathing muscle training to standard rehab helps people with rheumatoid arthritis who also have lung disease. Researchers will measure changes in exercise ability, breathlessness, and a specific gene (HOTAIR) linked to inflammation. About 39 ad…

This study looks at how a drink with caffeine and green tea extracts changes the way the body burns fat at rest, during exercise, and after exercise. Researchers will measure fat oxidation in 40 healthy adults aged 18 to 45 who are not highly active. The goal is to understand if …