EXERCISE

This study is testing whether a drug called tadalafil (often used for erectile dysfunction) combined with a home cycling program can help boys with Duchenne muscular dystrophy. The drug aims to improve blood flow to muscles, which is often poor in DMD, while exercise builds stren…

This study looks at whether a combination of physical exercise and a nutritional supplement (phenylcapsaicin) can improve body composition, metabolism, and overall health in adults aged 50-65 who are overweight but not obese. Participants must have at least two signs of mild meta…

This study tests whether doing specific core muscle exercises right after abdominal surgery can lower the chance of developing an incisional hernia and reduce long-term pain. About 588 adults having abdominal surgery will be randomly assigned to either standard care or a daily ex…

This study tests whether a dietary supplement called capsinoid, found in sweet peppers and chilies, can activate brown fat in obese adolescents. Brown fat is a type of body fat that burns calories to produce heat, which may help with weight control. The study will involve 38 teen…

This study compares two ways of doing aerobic exercise: before eating (fasted) versus after eating (fed). Over 16 weeks, 40 adults with obesity will follow a supervised exercise program. Researchers will measure changes in body fat, blood fats, blood pressure, and appetite hormon…

This study tests whether using a wearable fitness tracker, alone or with health coaching, helps adults aged 40+ with central obesity (belly fat) become more active and improve heart health markers. 133 participants will be split into three groups: one gets a Fitbit with coaching,…

This study tests whether a child-friendly core exercise program, delivered via video, can improve balance and mobility in children aged 6-12 with spastic cerebral palsy. Half of the 54 participants will do the Fun-Core exercises at home 3 times a week for 8 weeks, while the other…

This study tests whether a virtual assistant (a chatbot) can help adults aged 60 and older complete a 12-week home exercise program. Seventy participants will either use the virtual assistant or join a standard in-person class. The goal is to see if the tech-based approach improv…

This study looks at whether a structured 12-week exercise program can improve fitness and recovery in women who have had DIEP flap breast reconstruction after mastectomy. Half of the 78 participants will follow the exercise program, while the other half will receive standard care…

This study tests whether a special energy therapy called TECAR, combined with exercise, can reduce pain and improve function in people with tennis elbow (lateral epicondylitis). Sixty-two adults with elbow pain for at least 6 weeks will receive either real or sham TECAR therapy p…

This study tests whether a 4-week exercise program before surgery can reduce frailty and improve recovery in women with advanced ovarian cancer. Frailty affects about half of these patients and often leads to worse surgical outcomes and chemotherapy delays. The program includes l…

This study tests two different home exercise programs designed to prevent falls in people with Parkinson's disease. Thirty participants will do one of the programs for six weeks, and researchers will measure changes in balance, walking, and fear of falling. The goal is to find ou…

This 26-week study tests whether taking creatine daily and doing resistance training (weightlifting) can improve thinking, memory, and physical function in older adults with mild cognitive impairment. Two hundred participants aged 60+ will be randomly assigned to creatine or plac…

This study compares high intensity laser therapy to exercise for people with thumb osteoarthritis. The goal is to see which treatment better reduces pain and improves hand function. About 42 adults with thumb arthritis will be assigned to one of the two treatments and followed fo…

This study tests whether adding very short, intense exercise bursts (called 'exercise-snacks') to a standard weight-management program can improve physical fitness in obese adolescents. Forty-eight teens will either do six mini-exercise sessions daily for three weeks or just rece…

This study tests whether a 4-week breathing muscle training program can improve lung function, reduce shortness of breath, and lessen cravings in people with substance use disorder. Thirty-four adults receiving inpatient treatment will either do breathing exercises with a device …

This study tests whether adding whole-body vibration exercises to mineral bath therapy (balneotherapy) helps people with chronic low back pain feel better, move easier, and sleep more soundly. Sixty adults aged 18 to 65 with long-lasting back pain will be split into two groups: o…

This study looks at whether a drink containing caffeine and green tea extracts can increase how much fat your body burns at rest, during exercise, and after a workout. Researchers will measure fat burning in 40 healthy adults aged 18 to 45 who exercise moderately. The goal is to …

This study tests whether the BETY exercise program, which combines physical exercises with pain management and emotional support, can help people with knee osteoarthritis who recently received injections. Sixty adults with knee osteoarthritis will be enrolled. The goal is to see …

This study compares two treatments—kinesiotaping (a special tape) and peloidotherapy (mud therapy)—plus home exercises, against exercises alone for people with mild-to-moderate carpal tunnel syndrome. 90 adults will be randomly assigned to one of three groups. The goal is to see …

This study looks at whether qigong or multicomponent exercise training can improve physical and mental health in people with panic disorder. Researchers will enroll 60 adults diagnosed with panic disorder and have them do 8 weeks of exercise. The goal is to see if these activitie…

This study tests whether a 10-week tailored exercise program, done in-person or online, can help multiple myeloma patients maintain physical fitness, muscle mass, and quality of life while undergoing chemotherapy before a stem cell transplant. Researchers will enroll 30 adults in…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 6 weeks can improve lung function, muscle strength, and quality of life in people with hemiplegia (paralysis on one side) after a stroke. 54 adults who are at least 3 months post-stroke will be randomly …

This study is testing a lentil-based protein supplement in 48 healthy adults aged 18-45. Researchers want to see if it is safe and whether different doses can help control blood pressure and improve blood vessel function and exercise performance. Participants will take the supple…

This study looks at whether combining a stepped-care mental health program with an exercise plan can improve mood and physical activity in Latina cancer survivors. Twenty women who are currently in or recently finished cancer treatment will take part. The goal is to see if this a…

This study tests whether adding motivational counselling to a supervised virtual exercise program helps cancer survivors stay physically active. 236 survivors who have finished primary cancer treatment will be split into two groups: one gets standard exercise advice, the other ge…

This study tests whether a mobile app called BumptUp can help pregnant women who don't currently exercise become more active and improve their heart health. Fifty healthy women in their second trimester will either use the app for 8 weeks or receive no app. Researchers will measu…

This study tests whether a natural supplement can increase collagen production in the body after exercise. Twenty healthy adults will take the supplement or a placebo for a week while doing weight-bearing exercise. Researchers will measure collagen markers in the blood and use th…

This study tests an online training program designed to help primary health care workers in Brazil give better advice on physical activity and reducing sedentary time. Over 3,300 health professionals will take the self-paced course and have their counseling skills measured before…

This study looks at how physical activity and thinking skills change as people age, focusing on Hispanic and non-Hispanic adults aged 55-85. Researchers want to see if it's possible to enroll 100 volunteers and gather early data on aging patterns. The goal is to better understand…

This study will measure how much energy older adults use during mat and equipment-based Pilates sessions. Twenty men and women aged 60+ with Pilates experience will complete both types of Pilates and treadmill walking. Researchers will track calories burned, heart rate, and perce…

This pilot study from Colorado State University will test 20 healthy adults (ages 18-40) to see if cold temperatures change how the body burns fat during exercise, and whether that change differs between females and males. Participants will exercise in both a normal room and a ve…

This study looks at how the right side of the heart works in people with COPD, both at rest and during different levels of exercise. Researchers want to find patterns of heart strain to help develop better treatments in the future. About 60 adults aged 40 and older with COPD will…

This study explores whether mild low-oxygen (hypoxic) conditioning, alone or combined with exercise, can improve blood vessel function in the brains of inactive adults aged 60-80. Researchers will measure changes in brain blood flow and other health markers in 64 participants. Th…

This study looks at how the right side of the heart works in people with COPD, both at rest and during exercise. Researchers will use heart imaging and other tests to identify different patterns of heart dysfunction. The goal is to better understand these patterns so that future …

This study looks at how a heart hormone called atrial natriuretic peptide (ANP) affects metabolism and heart health. Researchers will test 200 adults with different genetic versions of ANP to see how their bodies respond to exercise and sugar. The goal is to understand why some p…

This small study tests whether using immersive virtual reality (IVR) can reduce the effort it takes to breathe while exercising. Ten healthy adults will cycle with and without a VR headset, and their breathing effort will be measured with a thin tube in the esophagus. The goal is…

This study looks at how different amounts of supervised indoor cycling change gut bacteria and related substances in healthy men aged 18 to 45. Participants will be placed into one of three groups: no structured training, moderate cycling, or high-load cycling. Researchers will m…

This study looks at how exercise and physical activity during and after pregnancy change the makeup of breast milk. Researchers want to see if these changes affect how babies use energy and grow, which could help prevent childhood obesity. The study will follow 200 mothers and th…

This study looks at whether high blood lactate levels in people with metabolic syndrome cause problems with fat breakdown and blood sugar control. Researchers will raise lactate levels in healthy volunteers using an IV infusion and then measure how their body handles fat and suga…

This study looks at whether the number of steps breast cancer patients take each day, tracked by a smartwatch, is linked to how well their treatment works. About 82 women with non-metastatic HER2-negative breast cancer will wear a Huawei Fit 2 smartwatch during chemotherapy befor…

This study tests whether different levels of exercise before surgery can increase immune cells inside oesophageal cancer tumors. Researchers will measure changes in fitness and immune response in 50 adults with resectable oesophageal adenocarcinoma. The goal is to find the best e…

This study looks at how doing mat Pilates for 8 weeks changes body awareness and physical activity levels in sedentary women ages 18-29. About 54 women will join, with half doing Pilates and half as a control group. Researchers will use surveys to measure changes in how women fee…

This study tests whether a short burst of aerobic exercise on a stationary bike and a 30-minute nap can improve how people with multiple sclerosis learn and remember a hand motor skill. Twenty adults with relapsing-remitting MS will take part. Researchers will measure brain and m…

This study looks at whether standard breathing exercises and extra muscle-strengthening breathing training can affect a specific gene (HOTAIR) in people with rheumatoid arthritis who also have lung disease. Researchers will compare two groups: one doing standard rehab and one add…

This study looks at how histamines, the same molecules that cause allergy symptoms, affect blood flow in the lungs after exercise. Researchers will measure heart function in 20 healthy adults aged 19-39 under two conditions: one with a histamine-blocking drug and one with a place…

This study looks at how blood sugar levels change during exercise in healthy adults and those with type 1 diabetes. Participants will cycle after a standard breakfast, and their glucose will be tracked with a continuous monitor and finger-prick tests. The goal is to see if the bo…

This study follows 700 people with chronic diseases like arthritis, diabetes, or heart disease for 4 years. Participants wear a small movement sensor for 5 days, three times a year, to track their physical activity and sedentary time. Researchers want to see if a person's unique …

This study looks at whether scheduling workouts based on menstrual cycle phases improves fitness in women who exercise regularly. About 111 female athletes will follow different training schedules over three cycles. Researchers will measure changes in aerobic fitness, muscle stre…