Breathing workouts may rewire genes in arthritis patients

NCT ID NCT07320846

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether standard breathing exercises and extra muscle-strengthening breathing training can affect a specific gene (HOTAIR) in people with rheumatoid arthritis who also have lung disease. Researchers will compare two groups: one doing standard rehab and one adding inspiratory muscle training. They will measure changes in gene expression, breathing capacity, pain, and quality of life over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pulmonary rehabilitation program and inspiratory muscle training

What this could lead to

If successful, this study could reveal how breathing exercises affect genes linked to inflammation, potentially guiding future treatments for rheumatoid arthritis-related lung disease.

What could go wrong

This is a small, early observational study (39 people) looking at genetic markers, not a treatment trial. Results may not lead to direct patient benefits or apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

interstitial lung disease Motor Activity rheumatoid arthritis rheumatoid arthritis-associated interstitial lung disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Health Sciences

    RECRUITING

    Istanbul, Turkey, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact