Breathing workouts may rewire genes in arthritis patients
NCT ID NCT07320846
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether standard breathing exercises and extra muscle-strengthening breathing training can affect a specific gene (HOTAIR) in people with rheumatoid arthritis who also have lung disease. Researchers will compare two groups: one doing standard rehab and one adding inspiratory muscle training. They will measure changes in gene expression, breathing capacity, pain, and quality of life over 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pulmonary rehabilitation program and inspiratory muscle training
- What this could lead to
- If successful, this study could reveal how breathing exercises affect genes linked to inflammation, potentially guiding future treatments for rheumatoid arthritis-related lung disease.
- What could go wrong
- This is a small, early observational study (39 people) looking at genetic markers, not a treatment trial. Results may not lead to direct patient benefits or apply to everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Health Sciences
RECRUITINGIstanbul, Turkey, Turkey (Türkiye)
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