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Simple Goal-Setting may cut Alzheimer's risk in midlife

NCT ID NCT05980052

Recruiting now Prevention Sponsor: Arizona State University Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether specific goal-setting techniques can help adults aged 45 to 65 become more physically active and stick with it. Participants are overweight or obese and currently get little exercise. They will receive a behavioral program designed to boost self-regulation and physical activity, with the long-term aim of reducing the risk of Alzheimer's disease and related dementias.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a behavioral program that uses goal-setting techniques to help people become more physically active
What this could lead to
If successful, this approach could help midlife adults maintain regular physical activity, potentially reducing their risk of Alzheimer's disease and related dementias.
What could go wrong
This is an early proof-of-concept study with a modest sample size, so results may not apply broadly. The intervention focuses on behavior change, which can be difficult to sustain long-term.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EXERCISE PHYSICAL ACTIVITY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arizona State University

    RECRUITING

    Phoenix, Arizona, 85004, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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